Le Yu

ORCID: 0009-0009-1635-2602
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About
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Research Areas
  • Microbial Metabolic Engineering and Bioproduction
  • Gene Regulatory Network Analysis
  • Gene expression and cancer classification
  • Biofuel production and bioconversion
  • Bioinformatics and Genomic Networks
  • Probabilistic and Robust Engineering Design
  • Lymphoma Diagnosis and Treatment
  • Microbial Metabolites in Food Biotechnology
  • CNS Lymphoma Diagnosis and Treatment
  • Viral Infectious Diseases and Gene Expression in Insects
  • Genetics, Bioinformatics, and Biomedical Research
  • Statistical Distribution Estimation and Applications
  • Power System Reliability and Maintenance
  • 3D Printing in Biomedical Research
  • Fractal and DNA sequence analysis
  • Optimal Power Flow Distribution
  • Maritime Navigation and Safety
  • Wind and Air Flow Studies
  • Risk and Safety Analysis
  • Traditional Chinese Medicine Analysis
  • Catalysis for Biomass Conversion
  • Bamboo properties and applications
  • Structural Health Monitoring Techniques
  • Machine Learning in Bioinformatics
  • Bacterial Genetics and Biotechnology

Southeast University
2015-2025

Beijing Chang'an Integrated Traditional Chinese and Western Medicine Hospital
2025

Sichuan University
2025

University of Electronic Science and Technology of China
2012-2024

Sichuan Cancer Hospital
2023-2024

Liaoning University
2024

WuXi AppTec (China)
2023-2024

State Forestry and Grassland Administration
2022-2023

Institute of Soil and Water Conservation
2023

Fujian Agriculture and Forestry University
2022-2023

The glucose-mediated carbon catabolite repression (CCR) in Clostridium tyrobutyricum impedes efficient utilization of xylose present lignocellulosic biomass hydrolysates. In order to relieve the CCR and enhance utilization, three genes (xylT, xylA, xylB) encoding a proton-symporter, isomerase xylulokinase, respectively, from acetobutylicum ATCC 824 were co-overexpressed with aldehyde/alcohol dehydrogenase (adhE2) C. (Δack). Compared strain Ct(Δack)-pM2 expressing only adhE2, mutant...

10.1002/bit.25613 article EN Biotechnology and Bioengineering 2015-04-20

High-quality cutaneous wound healing is associated with rapid closure and a comfortable process. Currently, exosomes derived from mesenchymal stem cells displayed prominent therapeutic effect on skin closure. But the approaches for itching are very limited in clinical. Stem human exfoliated deciduous teeth (SHED) may offer unique exosome resource cell-free therapeutics potential clinical applications. Here, we investigated common mechanisms underlying unpleasant sensation of itching,...

10.1186/s12951-022-01446-1 article EN cc-by Journal of Nanobiotechnology 2022-05-21

Cyber-attacks are becoming more persistent and complex.Most state-of-the-art attack forensics techniques either require annotating instrumenting software applications or rely on high quality execution profiling to serve as the basis for anomaly detection.We propose a novel technique ALchemist.It is based observations that builtin application logs provide critical high-level semantics audit low-level fine-grained information; two share lot of common elements.ALchemist hence log fusion couples...

10.14722/ndss.2021.24445 article EN 2021-01-01

Lipids increase osteoporosis and fracture risk, yet research on Atherogenic Index of Plasma (AIP), bone mineral density declines (BMD), trabecular score (TBS) is limited. This study examined the relationships between AIP, TBS, BMD in American adults using National Health Nutrition Examination Survey (NHANES) data, including effect obesity. Based data from 3,162 Americans, multivariable logistic regression a generalized additive model (GAM) were used to analyze BMD, TBS. Mediation studies...

10.1186/s13018-025-05460-5 article EN cc-by-nc-nd Journal of Orthopaedic Surgery and Research 2025-01-10

10.23919/eucap63536.2025.10999912 article EN 2022 16th European Conference on Antennas and Propagation (EuCAP) 2025-03-30

Reliability analysis of geaR tRansmission

10.17531/ein.2015.4.19 article EN cc-by Eksploatacja i Niezawodnosc - Maintenance and Reliability 2015-09-16

Wound healing is the treatment problem after deep second degree (II°) burns. The p38 mitogen-activated protein kinase (p38 MAPK) and nuclear factor-κB/inhibitory factor-κB (NF-κB/IκB) signal pathways play significant role in angiogenesis wound repair burns.This study aimed to investigate preparation, characterization pharmacodynamics of total flavonoids composite phospholipids liposome Oxytropis falcata Bunge (TFOFB-CPL) on II° burns research its biological activity underlying mechanism....

10.1080/03639045.2020.1841787 article EN Drug Development and Industrial Pharmacy 2020-10-23

Abstract Intensified fed‐batch (IFB), a popular cell culture intensification strategy, has been widely used for productivity improvement through high density inoculation followed by cultivation. However, such an strategy may counterproductively induce rapidly progressing apoptosis and difficult‐to‐sustain productivity. To improve performance, we developed novel process intermittent‐perfusion (IPFB) which incorporates one single or multiple cycles of intermittent perfusion during IFB better...

10.1002/bit.28605 article EN Biotechnology and Bioengineering 2023-11-23
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