A5100672577- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Prostate Cancer Treatment and Research
- Medical Imaging Techniques and Applications
- AI in cancer detection
- Glaucoma and retinal disorders
- Prostate Cancer Diagnosis and Treatment
- Orthopedic Surgery and Rehabilitation
- Advanced Neuroimaging Techniques and Applications
- Bone health and osteoporosis research
- Industrial Vision Systems and Defect Detection
- Advanced MRI Techniques and Applications
- Ocular Surface and Contact Lens
- Medical Image Segmentation Techniques
- Cardiac Imaging and Diagnostics
- Blood Pressure and Hypertension Studies
- Corneal surgery and disorders
- Simulation and Modeling Applications
- Cardiac Arrhythmias and Treatments
- Digital Radiography and Breast Imaging
- Sports injuries and prevention
- Cardiac Valve Diseases and Treatments
- Gallbladder and Bile Duct Disorders
- Cardiac pacing and defibrillation studies
- Fault Detection and Control Systems
University of Nottingham
2017-2025
Second Affiliated Hospital of Jilin University
2024-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2025
Wangjing Hospital of China Academy of Chinese Medical Sciences
2022-2025
Qingdao University
2025
Qingdao Municipal Hospital
2025
University of Electronic Science and Technology of China
2025
Southeast University
2025
Quzhou College of Technology
2025
Nanjing Medical University
2018-2025
OBJECTIVE Quantitative assessment of small fiber damage is key to the early diagnosis and progression or regression diabetic sensorimotor polyneuropathy (DSPN). Intraepidermal nerve density (IENFD) current gold standard, but corneal confocal microscopy (CCM), an in vivo ophthalmic imaging modality, has potential be a noninvasive objective image biomarker for identifying damage. The purpose this study was determine diagnostic performance CCM IENFD by using guidelines as reference standard....
Purpose.: To assess the diagnostic validity of a fully automated image analysis algorithm in vivo confocal microscopy images quantifying corneal subbasal nerves to diagnose diabetic neuropathy. Methods.: One hundred eighty-six patients with type 1 and 2 diabetes mellitus (T1/T2DM) 55 age-matched controls underwent assessment neuropathy bilateral (IVCCM). Corneal nerve fiber density (CNFD), branch (CNBD), length (CNFL) were quantified expert, manual, fully-automated analysis. The areas under...
Purpose: To establish intraobserver and interobserver repeatability, agreement, symmetry of corneal nerve fiber (NF) morphology in healthy subjects using vivo confocal microscopy. Methods: Nineteen underwent microscopy (Heidelberg Retinal Tomograph III Rostock Cornea Module) at baseline 7 days apart. Bland–Altman plots were generated to assess the intraclass correlation coefficient repeatability calculated estimate for NF density (numbers per square millimeter), branch (NBD; numbers length...
We describe and evaluate an automated software tool for nerve-fiber detection quantification in corneal confocal microscopy (CCM) images, combining sensitive nerve- fiber with morphological descriptors.We have evaluated the of Diabetic Sensorimotor Polyneuropathy (DSPN) using both new previously published features. The evaluation used 888 images from 176 subjects (84 controls 92 patients type 1 diabetes). patient group was further subdivided into those ( n = 63) without 29) DSPN.We achieve...
Deep learning has been employed to prognostic and health management of automotive aerospace with promising results. Literature in this area revealed that most contributions regarding deep is largely focused on the model's architecture. However, improvement different aspects learning, such as custom loss function for are scarce. There therefore an opportunity improve upon effectiveness system's prognostics diagnostics without modifying models' To address gap, use two dynamically weighted...
Gallstones are a prevalent health issue. Recent studies have revealed that blood pressure (BP) may affect gallstone formation. This study assessed the association between hypertension (HTN) and both prevalence of gallstones age at first cholecystectomy among U.S. adults. Data were extracted from National Health Nutrition Examination Survey (NHANES) database 2017 to 2020. Weighted logistic linear regression analyses subgroup employed investigate relationships HTN, disease (GD),...
Hepatic angiosarcoma is an extremely rare, uncontrollable tumor with strong invasion, high mortality rate, and poor prognosis. There first report on hepatic accompanied by eosinophilia. A woman a chief complaint of appetite for about 3 months presented to local hospital liver mass. Laboratory examination revealed significant increase in eosinophils count was 9.58% the serum. Abdominal MRI multiple focal high-density lesions spleen, cranial shadows skull. Laparoscopic biopsy targeted...
The aim of this study is to demonstrate the feasibility using continuous signals about thickness and pennation angle changes muscles detected in real-time from ultrasound images, named as sonomyography (SMG), characterize under isometric contraction, along with synchronized surface electromyography (EMG) generated torque signals. right biceps brachii seven normal young adult subjects were tested. We observed that exponential functions could well represent relationships between normalized EMG...
To prospectively compare the reproducibility of normal liver apparent diffusion coefficient (ADC) measurements by using different respiratory motion compensation techniques with multiple breath-hold (MBH), free-breathing (FB), respiratory-triggered (RT), and navigator-triggered (NT) diffusion-weighted (DW) imaging to ADCs at anatomic locations.The study protocol was approved institutional review board, written informed consent obtained from each participant. Thirty-nine volunteers underwent...
Objective: Corneal confocal microscopy (CCM), an in vivo ophthalmic imaging modality, is a noninvasive and objective biomarker for identifying small nerve fiber damage. We have evaluated the diagnostic performance of previously established CCM parameters to novel automated measure corneal complexity called fractal dimension (ACNFrD). Methods: A total 176 subjects (84 controls 92 patients with type 1 diabetes) without diabetic sensorimotor polyneuropathy (DSPN) underwent CCM. Fractal analysis...
The loss function plays an important role in deep learning models as it determines the model convergence behavior and performance. In semantic segmentation, many methods utilize pixel-wise (e.g. cross-entropy) region-wise dice) losses while boundary-wise is underexplored. It known that one of key aims segmentation to precisely delineate objects' boundaries. Hence, essential design a measures errors around Fuzzy rough sets are constituted by fuzzy equivalence relation, which commonly used...
To assess the effect of different antiplatelet strategies on clinical outcomes after coronary artery bypass grafting. Five year follow-up randomised Different Antiplatelet Therapy Strategy After Coronary Artery Bypass Grafting (DACAB) trial. Six tertiary hospitals in China; enrolment between July 2014 and November 2015; completion five from August 2019 to June 2021. 500 patients aged 18-80 years (including 91 (18.2%) women) who had elective grafting surgery completed DACAB Patients were...
Our aim was to prospectively evaluate the feasibility of diffusional kurtosis imaging (DKI) in normal human kidney and report preliminary DKI measurements. Institutional review board approval informed consent were obtained. Forty‐two healthy volunteers underwent diffusion‐weighted (DWI) scans with a 3‐T MR scanner. b values 0, 500 1000 s/mm 2 adopted. Maps fractional anisotropy (FA), mean diffusivity (MD), radial ( D ⊥ ), axial || (MK), K ) produced. Three representative slices upper pole,...
Silica aerogel composites have promising applications in high-temperature heat storage insulation. However, the impact of high temperatures and moisture on their insulation performance remains unclear. To reveal influences temperature absorption property transfer silica composites, an experimental numerical study was conducted to explore micromorphology, thermophysical parameters, characteristics, response. The service limit composite has been clarified. Measurements for thermal...
Abstract Prostate cancer is the second leading cause of death in men United States. The androgen receptor (AR) plays critical roles both early disease and advanced prostate cancer. Current therapeutic approaches targeting androgen/AR axis are initially effective, but castration resistant (CRPC) inevitably develops. CRPC linked with increased AR activity via gene overexpression, amplification, gain-of-function mutations. To address these mechanisms AR-dependent tumor growth, we have developed...
To define a threshold value of apparent diffusion coefficient (ADC) with which malignant breast lesions can be distinguished from benign lesions, and to evaluate the ADC change peri-tumor tissue in carcinoma by echo planar-diffusion weighted imaging (EPI-DWI). 57 were scanned routine MRI EPI-DWI. The values compared between lesions. sensitivity specificity EPI-DWI evaluated Receiver Operating Characteristic curve (ROC). lesion layered tissues (from innermost layer 1 outermost 4 5 mm every...
Abstract Background Intrapapillary capillary loop (IPCL) is an important factor for predicting invasion depth of esophageal squamous cell carcinoma (ESCC). The closely related to the selection treatment strategy. However, diagnosis IPCLs complicated and subject interobserver variability. This study aimed develop artificial intelligence (AI) system predict subtypes precancerous lesions superficial ESCC. Methods Images magnifying endoscopy with narrow band imaging from three hospitals were...
Lipids increase osteoporosis and fracture risk, yet research on Atherogenic Index of Plasma (AIP), bone mineral density declines (BMD), trabecular score (TBS) is limited. This study examined the relationships between AIP, TBS, BMD in American adults using National Health Nutrition Examination Survey (NHANES) data, including effect obesity. Based data from 3,162 Americans, multivariable logistic regression a generalized additive model (GAM) were used to analyze BMD, TBS. Mediation studies...
Despite accumulating evidence on central obesity and osteoporosis, the role of a body shape index (ABSI), nonlinear quantifying via mass (BMI), waist circumference (WC), height, remains controversial underexplored. Although recent meta-analyses suggest may modulate fracture risk bidirectionally, no research has comprehensively compared ABSI with traditional adiposity metrics, such as BMI, WC, waist-to-height ratio (WHtR), to predict site-specific changes in bone mineral density (BMD) across...