- Diet and metabolism studies
- Bariatric Surgery and Outcomes
- Diabetes Treatment and Management
- Pharmacology and Obesity Treatment
- Clinical Nutrition and Gastroenterology
- Pancreatitis Pathology and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Hip and Femur Fractures
- Child Nutrition and Feeding Issues
- Esophageal and GI Pathology
- Diabetes and associated disorders
- Gastric Cancer Management and Outcomes
- Nutrition, Genetics, and Disease
- Frailty in Older Adults
- Clinical practice guidelines implementation
- Dysphagia Assessment and Management
- Cancer, Lipids, and Metabolism
- Nutrition and Health in Aging
- Helicobacter pylori-related gastroenterology studies
- Metabolism, Diabetes, and Cancer
- Biomarkers in Disease Mechanisms
- Psoriasis: Treatment and Pathogenesis
- Body Composition Measurement Techniques
- Metastasis and carcinoma case studies
- Biochemical Acid Research Studies
University Hospital Leipzig
2011-2025
Leipzig University
2004-2023
Klinik und Poliklinik für Neurologie
2020
Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie
2020
Advanced Dermatology
2019
Obesity and high abdominal fat mass are risk factors for developing the chronic inflammatory skin disease psoriasis. They associated with increased incidence, prevalence severity of disease. A positive effect weight loss on psoriasis activity has been shown in several studies. Obesity-related such as dysregulation glucose lipid metabolism, activation adipose tissue resultant persistent low-grade inflammation have discussed links obesity diseases. Recently, we demonstrated a critical role...
Abstract Background Endoscopic full-thickness transoral outlet reduction (efTOR) is a therapeutic option to reduce dilated gastrojejunal anastomosis (GJA) after Roux-en-Y gastric bypass (RYGB). Mucosal ablation with argon plasma coagulation (APC) usually performed achieve tissue adaptation. However, rupture of sutures before scarring can lead recurrent dilatation the GJA. Here, we describe efTOR semicircumferential endoscopic submucosal dissection (ESD-efTOR) as an alternative APC-efTOR....
NOTICE OF UPDATE The DDG clinical practice guidelines are updated regularly during the second half of calendar year. Please ensure that you read and cite respective current version.
Abstract Aim To compare the effectiveness of strength versus endurance training on reducing visceral fat in individuals with obesity. Materials and Methods For STrength ENdurance (STEN) 24‐month randomized clinical trial, we assigned 239 participants abdominal obesity to either or (two three times a week, 60 min/training session) addition standard nutritional counselling promote healthy diet. Changes adipose tissue (VAT) area quantified by magnetic resonance imaging after 12 months were...
Patients with malignant tumors of the upper gastrointestinal tract are at risk weight loss. Early supportive nutrition therapy is therefore recommended and usually requires placement a percutaneous endoscopic gastrostomy (PEG). The aim this study was to compare adverse events usage characteristics direct puncture technique those traditional pull when used in patients endoscopically passable tumors. primary endpoint rate inflammatory (AEs) fistula. secondary long-term puncture-site...
Aktualisierungshinweis Die DDG-Praxisempfehlungen werden regelmäßig zur zweiten Jahreshälfte aktualisiert. Bitte stellen Sie sicher, dass jeweils die neueste Version lesen und zitieren.
Aktualisierungshinweis Die DDG-Praxisempfehlungen werden regelmäßig zur zweiten Jahreshälfte aktualisiert. Bitte stellen Sie sicher, dass jeweils die neueste Version lesen und zitieren.
Weight reduction is an integral part of the therapy many patients with type 2 diabetes. The effectiveness weight in treatment and prevention diabetes has been proven by studies. In "Finnish Diabetes Prevention Study", conversion prediabetes to was reduced 58% through lifestyle intervention [1]. Similar results were obtained "Diabetes Program" [2]. An English study showed that for every 1 kg lost first year after diagnosis diabetes, life expectancy increases 3−4 months [3], Williamson et al....
Background: The refeeding syndrome (RFS) is an oftentimes-unrecognized complication of reintroducing nutrition in malnourished patients that can lead to fatal cardiovascular failure. We hypothesized a clinical decision support system (CDSS) improve RFS recognition and management. Methods: developed algorithm from current diagnostic criteria for detection, tested the on retrospective dataset combined final with therapy referral recommendations knowledge-based CDSS. CDSS integration into...
Gewichtsreduktion ist ein integraler Bestandteil in der Therapie vieler Patienten mit Typ-2-Diabetes. Die Effektivität einer Behandlung und Prävention des Typ-2-Diabetes durch viele Studien belegt. In "Finnish Diabetes Prevention Study" konnte die Konversion eines Prädiabetes einen eine Lebensstilintervention um 58 % gesenkt werden [1]. Ähnliche Ergebnisse erbrachte das "Diabetes Program" [2]. Eine englische Studie belegen, dass pro 1 kg im 1. Jahr nach Diagnose Lebenserwartung 3–4 Monate...
So einfach wie komplex zugleich gestaltet sich die Ernährungstherapie bei Menschen mit Übergewicht und Adipositas. Während das Ziel der Adipositastherapie in einer Gewichtsabnahme Verbesserung des Gesundheitszustandes anschließender Gewichtsstabilisierung liegt, sind Patienten täglich herausfordernden Situationen im Alltag konfrontiert teilweise überfordert. Deshalb müssen patientenzentrierte Therapieziele individuell festgelegt den Betroffenen besprochen werden. Auch wenn es...
Drug therapy in patients who have undergone bariatric surgery is challenging. We aimed to investigate the patients' perspective on their drug therapy. This should allow deriving tailored measures better support and healthcare professionals with after surgery. conducted a quantitative telephone-based interview study The consisted of assessments three parts: (i) current therapy: prescription, administration adherence, (ii) changes (iii) adverse events. 105 enrolled were taking median 10...
Einleitung: Bei Karzinomen des oberen Gastrointestinaltraktes (oGIT) werden bei eingeschränkter Fähigkeit zur oralen Nahrungsaufnahme die Fadendurchzugsmethode (FDM) oder – endoskopisch nicht passierbaren Stenosen das Direktpunktionsverfahren (DPV) angewandt. Neben infektiösen Komplikationen besteht der FDM in ca. 1% Fälle Risiko Metastasierung den gastrokutanen Fistelkanal. Beim DPV Passage Tumors und Kontamination PEG mit Mundflora umgangen.