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Pavel G. Feskin

ORCID: 0009-0009-2821-0097
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About
Contact & Profiles
A5093063578
Research Areas
  • RNA and protein synthesis mechanisms
  • Plant Virus Research Studies
  • Glycosylation and Glycoproteins Research
  • Genomics and Chromatin Dynamics
  • Antimicrobial Peptides and Activities

Lomonosov Moscow State University
 2023-2024

 Interactions of Nucleosomes with Acidic Patch-Binding Peptides: A Combined Structural Bioinformatics, Molecular Modeling, Fluorescence Polarization, and Single-Molecule FRET Study
OPENALEX - Publications 
Pavel D. Oleinikov Anastasiia S. Fedulova Grigoriy A. Armeev Nikita A. Motorin Lovepreet Singh-Palchevskaia and 9 more Anastasiia L. Sivkina Pavel G. Feskin Г. С. Глухов Dmitry A. Afonin Galina A. Komarova М. П. Кирпичников Vasily M. Studitsky Alexey V. Feofanov Alexey К. Shaytan

In eukaryotic organisms, genomic DNA associates with histone proteins to form nucleosomes. Nucleosomes provide a basis for genome compaction, epigenetic markup, and mediate interactions of nuclear their target loci. A negatively charged (acidic) patch located on the H2A-H2B dimer is characteristic feature nucleosomal surface. The acidic common site in attachment various chromatin proteins, including viral ones. Acidic patch-binding peptides present perspective compounds that can be used...

10.3390/ijms242015194 article EN International Journal of Molecular Sciences 2023-10-14
 Interactions of nucleosomes with acidic patch binding peptides: Combining structural analysis, MD simulations, and experiments
OPENALEX - Publications 
Alexey К. Shaytan Grigoriy A. Armeev Pavel D. Oleinikov Nikita A. Motorin Lavprit Singh-Palchevskaya and 9 more Anastasiia L. Sivkina Pavel G. Feskin Galina A. Komarova М. П. Кирпичников Alexey V. Feofanov Dmitry A. Afonin Anastasiia S. Fedulova Vasily M. Studitsky Г. С. Глухов

10.1016/j.bpj.2023.11.150 article EN publisher-specific-oa Biophysical Journal 2024-02-01
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