Zhen Luo

ORCID: 0009-0009-3175-0369
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Research Areas
  • Nanoplatforms for cancer theranostics
  • Photodynamic Therapy Research Studies
  • Cancer, Hypoxia, and Metabolism
  • Peptidase Inhibition and Analysis
  • Antimicrobial Resistance in Staphylococcus
  • Advanced Welding Techniques Analysis
  • Pediatric Urology and Nephrology Studies
  • Urological Disorders and Treatments
  • Plant biochemistry and biosynthesis
  • Family and Disability Support Research
  • Dielectric materials and actuators
  • Bacterial Identification and Susceptibility Testing
  • Microbial Metabolic Engineering and Bioproduction
  • Platelet Disorders and Treatments
  • Signaling Pathways in Disease
  • Photoacoustic and Ultrasonic Imaging
  • Cancer Mechanisms and Therapy
  • Blood groups and transfusion
  • Advanced Sensor and Energy Harvesting Materials
  • Prenatal Screening and Diagnostics
  • Immune Cell Function and Interaction
  • Air Quality and Health Impacts
  • Electromagnetic wave absorption materials
  • Tuberous Sclerosis Complex Research
  • Historical Medical Research and Treatments

Shanghai Jiao Tong University
2024-2025

First People’s Hospital of Zunyi
2022-2025

Zunyi Medical University
2022-2025

Chinese Academy of Medical Sciences & Peking Union Medical College
2024

Reproductive & Genetic Hospital CITIC-Xiangya
2024

Fujian Agriculture and Forestry University
2023

East China University of Science and Technology
2023

Tsinghua University
2023

Infinitus (China)
2023

Army Medical University
2022

A scalable high-temperature capacitor film based on grafted polypropylene is synthesized by a water-solid phase suspension grafting method, exhibiting discharged energy density above 90% efficiency of 4.5 J cm −3 at 125 °C after biaxial stretching.

10.1039/d3ta00437f article EN Journal of Materials Chemistry A 2023-01-01

Congenital primary obstructive megaureter (POM) is characterized by distal ureteral obstruction, leading to dilation, hydronephrosis, and potential renal impairment. Surgical intervention necessary for severe hydronephrosis (SFU grade III-IV) or progressive decline. Open reimplantation the standard treatment but associated with significant surgical trauma prolonged recovery. This study evaluates safety efficacy of transabdominal laparoscopic (TALUR) at posterior wall-bladder dome compares...

10.3389/fped.2025.1552433 article EN cc-by Frontiers in Pediatrics 2025-04-07

Primary palmar hyperhidrosis (PPH) is a somatic condition characterized by excessive sweating of the hands. It mainly affects adolescents and young adults rarely observed among children. This significantly impairs patients' academic performance, daily activities, social interactions can even lead to insurmountable psychological burdens. Surgical intervention for PPH typically reserved individuals aged 16 years older, as compensatory occurs at high rate (65%) postoperatively children younger...

10.3389/fmed.2025.1542064 article EN cc-by Frontiers in Medicine 2025-04-15

To evaluate the clinical efficacy and safety of autologous platelet-rich plasma (PRP) as an adjunctive treatment for penile hypospadias repair in children, to explore its independent role reducing postoperative complications. We retrospectively analyzed data from 103 pediatric patients undergoing between December 2019 2021 at Affiliated Hospital Zunyi Medical University. All received standard straightening tubularized incised plate (TIP) urethroplasty. Patients study group (n = 53)...

10.3389/fped.2025.1470092 article EN cc-by Frontiers in Pediatrics 2025-04-30

Taxadiene is an important precursor for the biosynthesis of highly effective anticancer drug paclitaxel, but its microbial yield very low. In this study, we employed

10.1016/j.synbio.2023.04.002 article EN cc-by-nc-nd Synthetic and Systems Biotechnology 2023-04-27

Abstract CD36 may defect on platelets and/or monocytes in healthy individuals, which was defined as deficiency. However, we did not know the correlation between molecular and protein levels completely. Here, aim to determine polymorphisms of gene, RNA level, plasma. The individuals were sequenced by Sanger sequencing. Bioinformational analysis used HotMuSiC, CUPSAT, SAAFEC-SEQ, FoldX. detection performed qPCR, flow cytometry, ELISA. In this study, found c.1228_1239 del ATTGTGCCTATT (allele...

10.1038/s41598-024-58491-z article EN cc-by Scientific Reports 2024-04-12

Background A variety of proteins including epigenetic factors are involved in the differentiation human bone marrow mesenchymal stem cells. These cells also exhibited an plasticity that enabled them to trans-differentiate from adipocytes osteoblasts (and vice versa) after commitment. Further in-depth study their alterations may make sense. Methods Chromatin Immunoprecipitation-PCR (ChIP-PCR) was used detect methylation enrichment status H3K9me2 Runx2 promoter, alizarin red and alkaline...

10.7717/peerj.13862 article EN cc-by PeerJ 2022-10-05

To understand the contribution of different sub-assemblages (sub-communities) in shrub and herb layers to distribution patterns community species richness stability Pinus massoniana Lamb. community, this study was carried out by using 160 quadrats (5 m × 5 m) 200 (1 1 m). These were selected from 40 plots on six islands. In study, common rare classified according frequency, “new communities” formed adding or removing species. Then changes analyzed. A redundancy analysis also used explore...

10.3390/su151813994 article EN Sustainability 2023-09-21

Abstract Because of its potent antioxidant effects, lycopene has been used in various industries including, but not limited to, food, medical, and cosmetic industries. Yarrowia lipolytica , a non-conventional yeast species, is promising chassis due to natural mevalonate (MVA) pathway, abundant precursor acetyl coenzyme A content, oleaginous properties. Several gene editing tools have developed for Y. along with engineering strategies tetraterpenoid production. In this study, we engineered...

10.1186/s40643-023-00697-6 article EN cc-by Bioresources and Bioprocessing 2023-11-24

CD36 is a multifunctional receptor expressed on the surface of many cell types. Among healthy individuals, may be absent platelets and monocytes (type I deficiency) or alone II deficiency). However, exact molecular mechanisms underlying deficiency remain unclear. In this study, we aimed to identify individuals with investigate basis it. Blood samples were collected from platelet donors at Kunming Center. Platelets isolated CD36-expression levels analyzed using flow cytometry. DNA whole blood...

10.1080/09537104.2023.2176168 article EN cc-by Platelets 2023-02-22

We thank Brantingham et al. for their interest in our study; we agree that both molecular and archaeological evidence should be used to understand the demographic history of Tibetan people. Our Report focused not on population, but rather selection acting specific putatively adaptive mutations segregating population. included some limited analyses because they helped illuminate results regarding natural selection. The real model is clearly likely more complex than simple models two...

10.1126/science.329.5998.1467-b article EN Science 2010-09-16

Wire arc additive manufacturing technology with cold metal transfer and pulse welding (CMT+P) is a promising for fabricating complex structures. In this paper, lot of basic research was conducted on the corner-constrained unconstrained zones 4043 aluminum alloy made using CMT+P. particular, microstructure morphology mechanical properties by CMT+P were studied thermal field emission scanning electron microscope, microhardness tester, etc. The results showed that there cellular crystals at...

10.3390/met12091423 article EN cc-by Metals 2022-08-28

Introduction To investigate the therapeutic effect of clitoris exposure + episioplasty dermabrasion platelet-rich plasma (PRP) injection chemexfoliation on vulvar lichen sclerosus (VLS). Methods Twenty children with VLS (under 14 years old) at our hospital from July 2020 to November 2022 were enrolled and treated PRP chemexfoliation. Additionally, symptomatic changes improvements in signs recorded. Results Significant effects achieved all this study. The Cattanco score was 8.02 ± 1.22 points...

10.3389/fped.2023.1276786 article EN cc-by Frontiers in Pediatrics 2023-12-04

Background: Preimplantation genetic testing (PGT) can reduce the risk of familial diseases, chromosome abnormalities, and recurrent abortions. It is unclear whether counselees with PGT indications understand accept implications PGT. A well-developed validated tool needed to evaluate knowledge, attitude, practice (KAP) levels indications. The purpose this study was develop validate a KAP questionnaire (PGT-KAP-Q) for Methods: First, we established an item pool based on literature review...

10.2139/ssrn.4709952 preprint EN 2024-01-01

Abstract Infection caused by drug-resistant Staphylococcus aureus is a rapidly developing public health and veterinary concern. Lack of comprehensive understanding the mechanisms underlying emergence strains, it makes S. one most intractable pathogenic bacteria. To identify mutations that confer resistance to anti-S.aureus drugs, we established laboratory-based adaptive evolution system performed 10 rounds experiments against 15 clinically used antibiotics. We discovered panel known novel...

10.21203/rs.3.rs-3940607/v1 preprint EN cc-by Research Square (Research Square) 2024-02-12

Abstract Objective To explore the underlying mechanism behind fine particulate matter’s (PM2.5)-mediated regulation of reproductive function in male rats, and to determine role vitamins this process. Methods In all, 32 SD rats were randomized a control cohort (normal saline), Vit (vitamin C at 100 mg/kg + vitamin E 50 mg/kg), PM2.5 (PM2.5 10 PM2.5+Vit exposure with eight each cohort. After four weeks exposure, mating experiments carried out. Thereafter, euthanized, testis epididymis tissues...

10.1101/2024.11.02.621651 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2024-11-04

To compare the efficacy of two different surgical approaches during and after pyeloplasty according to degree/severity hydronephrosis factor. Sixty child patients with UPJ obstruction admitted our hospital from August 2019 October 2021 were collected. Patients who underwent retroperitoneal laparoscopic (RPLP) enrolled into Group A (n = 20), while those received transperitoneal (TLP) selected as B 40). Clinical parameters, including gender, age, laterality obstruction, hydronephrosis, body...

10.3389/fped.2022.966292 article EN cc-by Frontiers in Pediatrics 2022-08-04
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