A5003789074- Parasite Biology and Host Interactions
- Parasitic Diseases Research and Treatment
- Parasites and Host Interactions
- Vector-Borne Animal Diseases
- Animal Disease Management and Epidemiology
- Virus-based gene therapy research
University Hospital Bonn
2021-2024
Despite long-term mass drug administration programmes, approximately 220 million people are still infected with filariae in endemic regions. Several research studies have characterized host immune responses but a major obstacle for on human has been the inability to obtain adult worms which turn hindered analysis infection kinetics and signalling. Although Litomosoides sigmodontis filarial mouse model is well-established, complex immunological mechanisms associated control disease...
Antibody-based fluorescence analysis of female reproductive tissues in research sexually transmitted diseases allows for an in-depth understanding protein localization, interactions, and pathogenesis. However, many cases, cryosectioning is not compatible with biosafety regulations; at all times, exposure lab personnel the public to potentially harmful pathogens from biological infectious material must be avoided; thus, formaldehyde fixation essential. Due formaldehyde’s cross-linking...