Y Chen

ORCID: 0009-0009-4238-5803
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About
Contact & Profiles
Research Areas
  • Esophageal and GI Pathology
  • Gallbladder and Bile Duct Disorders
  • Cardiac Health and Mental Health
  • Cardiovascular Health and Risk Factors
  • Colorectal Cancer Treatments and Studies
  • Gastroesophageal reflux and treatments
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Iron Metabolism and Disorders
  • Pancreatic and Hepatic Oncology Research
  • Dysphagia Assessment and Management
  • Gastrointestinal Tumor Research and Treatment
  • Regulation of Appetite and Obesity
  • Heart Rate Variability and Autonomic Control
  • COVID-19 and Mental Health
  • Adipokines, Inflammation, and Metabolic Diseases
  • Neuroendocrine Tumor Research Advances
  • Resilience and Mental Health
  • Long-Term Effects of COVID-19
  • Advanced Breast Cancer Therapies

McGill University
2018-2024

Abstract Background Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) is an emerging modality for the treatment of malignant gastric outlet obstruction (GOO), which combines benefits traditional treatments by providing a robust bypass using minimally invasive, endoscopic approach. The health economic aspects this new compared to approaches are not known. Aims To conduct cost-consequence analysis compare costs and EUS-GE, surgical gastrojejunostomy (SGJ) enteral stenting (ES) management...

10.1093/jcag/gwad061.102 article EN cc-by Journal of the Canadian Association of Gastroenterology 2024-02-14

Abstract Background Malignant gastric outlet obstruction is a morbid complication of pancreatic cancer. There currently lack epidemiology data characterizing its incidence and outcomes in patients with unresectable head cancer undergoing chemotherapy leucovorin, fluorouracil, irinotecan, oxaliplatin (FOLFIRINOX). Determining the MGOO this context crucial for developing effective management strategies. Aims We aim to ascertain treated FOLFIRINOX. Secondary objectives include evaluating...

10.1093/jcag/gwad061.156 article EN cc-by Journal of the Canadian Association of Gastroenterology 2024-02-14

Peroral endoscopic myotomy (POEM) is an effective minimally invasive alternative modality to Heller for the treatment of achalasia. However, efficacy POEM in non-achalasia esophageal motility disorders has not yet been well demonstrated. These include spastic conditions such as esophagogastric junction outflow obstruction (EGJOO), diffuse spasm (DES), and Jackhammer esophagus (JE). The objective this international multicenter study was assess clinical outcomes patients with disorders, namely...

10.1093/jcag/gwy009.004 article EN cc-by-nc-nd Journal of the Canadian Association of Gastroenterology 2018-02-01

Abstract Background Endoscopic enteral stenting is the standard of care for gastric outlet obstruction (GOO) despite high risks stent dysfunction and need re-intervention. ultrasound-guided gastroenterostomy (EUS-GE) a novel technique that has potential to decrease risk due tumor tissue in-/over-growth. EUS-GE; however, technically challenging thereby limiting its widespread use. Aims To describe use EUS-GE in management GOO using widely available vascular balloon catheter aims demonstrate...

10.1093/jcag/gwz047.175 article EN cc-by-nc-nd Journal of the Canadian Association of Gastroenterology 2020-02-01

Abstract Background Single-operator cholangioscopy assisted electrohydraulic lithotripsy is the standard of care for difficult common bile duct (CBD) stones with failed clearance using ERCP. This technology expensive and optimal timing its use in terms cost-effectiveness management algorithm patients CBD remains unclear Aims To determine cost-effective SOC-EHL utilization Methods A decision model was developed assessing 4 strategies progressively delayed introduction relation to ERCP over...

10.1093/jcag/gwz047.273 article EN cc-by-nc-nd Journal of the Canadian Association of Gastroenterology 2020-02-01

Abstract Background Endoscopic ultrasound-guided biliary drainage (EUS-BD) is a promising alternative to endoscopic retrograde cholangiopancreatography (ERCP) in malignant distal obstruction (MDBO). Recent small randomized controlled trials comparing EUS-BD with ERCP suggest that achieves similar technical success rate and safety profile while potentially being associated lower rates of stent dysfunction However, its application clinical practice has been impeded by various undefined...

10.1093/jcag/gwz047.278 article EN cc-by-nc-nd Journal of the Canadian Association of Gastroenterology 2020-02-01
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