A5111166143- Peptidase Inhibition and Analysis
- Glycosylation and Glycoproteins Research
- Carbohydrate Chemistry and Synthesis
- Natural product bioactivities and synthesis
- Epigenetics and DNA Methylation
- Proteoglycans and glycosaminoglycans research
- Bladder and Urothelial Cancer Treatments
Southern Medical University
2025
Kunming Medical University
2023
Second Affiliated Hospital of Kunming Medical College
2023
Bladder cancer is one of the most common malignant tumors urinary system and associated with a poor prognosis once invasion distant metastases occur. Epithelial-mesenchymal transition (EMT) drives metastasis in bladder cancer. Transforming growth factor β1 (TGF-β1) stromal fibroblasts, especially cancer-associated fibroblasts (CAFs), are positive regulators EMT However, it remains unclear how TGF-β1 mediates crosstalk between cells CAFs induces fibroblast-mediated We aimed to investigate...
Abstract Early-stage lung adenocarcinoma (LUAD) generally has a favorable prognosis. However, more than 30% of early-stage LUAD cases relapse within 5 years initial treatment, even following complete removal the primary tumor. Identification factors contributing to metastasis is needed develop effective prevention and treatment strategies. Here, we found upregulation xylosyltransferase 1 (XYLT1), glycosyltransferase that initiates biosynthesis sulfated glycosaminoglycan (sGAG) chains, in...
<p>Supplementary Figure 1 to 7, and Supplementary Materials Methods</p>
<div>Abstract<p>Early-stage lung adenocarcinoma generally has a favorable prognosis. However, more than 30% of early-stage cases relapse within 5 years initial treatment, even after complete removal the primary tumor. Identification factors contributing to metastasis is needed develop effective prevention and treatment strategies. In this study, we found upregulation xylosyltransferase 1 (XYLT1), glycosyltransferase that initiates biosynthesis sulfated glycosaminoglycan (sGAG)...