A5081678859- LGBTQ Health, Identity, and Policy
- HIV/AIDS Research and Interventions
- Sexuality, Behavior, and Technology
- Sarcoma Diagnosis and Treatment
- Protein Degradation and Inhibitors
- Bone Tumor Diagnosis and Treatments
- COVID-19 and Mental Health
- Pancasila Values in Education
- SARS-CoV-2 and COVID-19 Research
- Reproductive Health and Technologies
- COVID-19 epidemiological studies
- Homelessness and Social Issues
- Child Development and Digital Technology
- Criminal Justice and Corrections Analysis
- Child and Adolescent Psychosocial and Emotional Development
- Ethics in Clinical Research
- Family and Disability Support Research
- Resilience and Mental Health
- COVID-19 Clinical Research Studies
- SARS-CoV-2 detection and testing
Yale University
2021-2024
University of California, San Francisco
2017-2023
San Francisco AIDS Foundation
2019-2022
COVID-19 is a global crisis of unimagined dimensions. Currently, Remedesivir only fully licensed FDA therapeutic. A major target the vaccine effort SARS-CoV-2 spike-hACE2 interaction, and assessment efficacy relies on time consuming neutralization assay. Here, we developed cell fusion assay based upon interaction. The system was tested by transient co-transfection 293T cells, which demonstrated good correlation with standard spike pseudotyping for inhibition sera biologics. Then established...
Transgender women are disproportionately affected by HIV and less likely to be optimally engaged in care than other groups because of psychosocial challenges. With community collaboration, we developed Healthy Divas, an individual-level intervention increase healthcare empowerment gender affirmation improve engagement care. Divas comprises 6 peer-led individual sessions one group workshop facilitated a provider with expertise transgender health.To test the intervention's efficacy, conducted...
Incarceration is a significant public health issue that disproportionately impacts transgender (trans) women, particularly those of color. The cycle incarceration interacts with high levels substance use, mental illness, and HIV to produce disease burden among trans but, date, there are no published studies trans-specific reentry support interventions. Informed by the Model Gender Affirmation, we systematically adapted pilot tested evidence-based Project START intervention create Girlfriends...
Brachyury is an oncogenic transcription factor whose overexpression drives chordoma growth. The downmodulation of brachyury in cells has demonstrated therapeutic potential, however, as a it classically deemed "undruggable". Given that direct pharmacological intervention against proven difficult, attempts at have instead targeted upstream kinases. Recently, afatinib, FDA-approved kinase inhibitor, been shown to modulate levels multiple cell lines. Herein, we use afatinib lead undertake...
Introduction: Transgender women (assigned “male” at birth but who do not identify as male) are disproportionately impacted by HIV and experience unique barriers facilitators to care engagement. In formative work, we identified culturally specific modifiable treatment engagement among transgender living with (TWH), including prioritizing transition-related healthcare over treatment, avoiding settings due gender-related stigma, concerns about potential drug interactions hormones, inadequate...
Abstract Brachyury is an oncogenic transcription factor whose overexpression drives chordoma growth. The downmodulation of brachyury in cells has demonstrated therapeutic potential, however, as a it classically deemed “undruggable”. Given that direct pharmacological intervention against proven difficult, attempts at have instead targeted upstream kinases. Recently, afatinib, FDA‐approved kinase inhibitor, been shown to modulate levels multiple cell lines. Herein, we use afatinib lead...
Effective communication between schools and parents Is crucial for fostering understanding, trust, collaboration to enhance educational outcomes student well-being, especially during crises such as the COVID-19 pandemic. Moreover, current level of families is frequently insufficient, exacerbating difficulties in parental engagement, comprehension, certain policy implementation. This deficiency becomes even more pronounced due added stressors. study aims highlight challenges engagement...
Background: As a result of the COVID-19 pandemic, educational systems worldwide were disrupted. Students, educators, and parents faced challenges from rapid switch to distance learning with attendant social isolation limited teacher or peer interaction, along excessive demand worries lasting pandemic. It exacerbated preexisting mental health crises within school communities. Amidst such challenges, psychiatrists prescribed tailored medication regimens manage individual in time crisis,...