Louisa Z. Y. Huang

ORCID: 0009-0009-5419-7105
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Research Areas
  • Bone Tissue Engineering Materials
  • Bacterial biofilms and quorum sensing
  • Nanoparticles: synthesis and applications
  • Quantum Dots Synthesis And Properties
  • Force Microscopy Techniques and Applications
  • TiO2 Photocatalysis and Solar Cells
  • Laser-Ablation Synthesis of Nanoparticles
  • Nanoplatforms for cancer theranostics
  • Nanotechnology research and applications
  • Antimicrobial Peptides and Activities
  • Biosensors and Analytical Detection
  • Chemical and Physical Properties in Aqueous Solutions
  • Antibiotic Use and Resistance
  • Silk-based biomaterials and applications
  • Electrochemical Analysis and Applications
  • Dental materials and restorations
  • Additive Manufacturing and 3D Printing Technologies
  • Nanowire Synthesis and Applications
  • Ionic liquids properties and applications
  • Advanced Photocatalysis Techniques
  • Bacillus and Francisella bacterial research
  • Antimicrobial agents and applications
  • Wound Healing and Treatments
  • Antibiotic Resistance in Bacteria
  • Graphene and Nanomaterials Applications

RMIT University
2020-2025

MIT University
2020

Abstract Current treatment modalities of cutaneous wound infections are largely ineffective, attributed to the increasing burden antimicrobial resistance. S. aureus , a commonly wound‐associated pathogen continues pose clinical challenge, suggesting that new alternative therapeutic materials urgently required provide optimal treatment. A layered allotrope phosphorus termed Black Phosphorus nanoflakes (BPNFs) has emerged as potential antibacterial material. However, wider deployment this...

10.1002/adtp.202300235 article EN cc-by Advanced Therapeutics 2023-08-10

Additively manufactured titanium implant materials are rapidly advancing prosthetics and orthopaedic devices by making them more cost-effective customisable. However, the surface finish of printed via Selective Laser Melting (SLM) currently limits their integration into medical device field. Printing parameters, such as build angle inclination, can cause variations in roughness a part, often exceeding what is suitable for materials. Excessive promote microbial attachment proliferation,...

10.1016/j.jcis.2025.137866 article EN cc-by Journal of Colloid and Interface Science 2025-05-11

Gallium-based liquid metals (LMs) have emerged as novel materials for biomedical applications. Gallium (Ga) is considered significantly less toxic than other LMs, such mercury. However, Ga droplets not been thoroughly assessed their cytotoxicity. Here, we report the concentration-dependent cytotoxic effects of nano- and microdroplets on HaCaT cells, a human keratinocyte cell line. We found that demonstrated substantial at 1000 μg/mL after 24 h exposure, while lower concentrations 500...

10.1021/acsanm.2c03662 article EN ACS Applied Nano Materials 2022-11-01

The small size of the nanoparticles used to obtain high surface area photocatalysts makes their removal from solution difficult. Producing on substrates would alleviate this limitation. Adding heterojunctions photocatalysts, for example, TiO

10.1016/j.jcis.2024.11.079 article EN cc-by Journal of Colloid and Interface Science 2024-11-13

Naturally occurring and synthetic nanostructured surfaces have been widely reported to resist microbial colonization. The majority of these studies shown that both bacterial fungal cells are killed upon contact subsequent surface adhesion such surfaces. This occurs because the presence high-aspect-ratio structures can initiate a self-driven mechanical rupture during adsorption process. While this technology has received large amount scientific medical interest, one important question still...

10.1021/acsabm.3c00943 article EN ACS Applied Bio Materials 2023-12-15

The rise of antibiotic resistance in pathogenic bacteria requires new therapeutics to be developed. Several metallic nanoparticles such as those made from silver, copper, and zinc have shown significant antibacterial activity, part due metal ion leaching. Ga3+ containing compounds also been properties. Accordingly, it is estimated that Ga droplets may antibacterial, some studies date confirmed this. Here, multiple concentrations were tested against the resistant Gram-positive...

10.1021/acsami.3c15497 article EN ACS Applied Materials & Interfaces 2023-12-19

In the fight against drug-resistant pathogenic bacterial and fungal cells, low-dimensional materials are emerging as a promising alternative treatment method. Specifically, few-layer black phosphorus (BP) has demonstrated its effectiveness wide range of cells with studies suggesting low cytotoxicity towards healthy mammalian cells. However, antimicrobial mechanism action BP is not well understood. Before new applications for this material can be realised, further in-depth investigations...

10.1039/d1tb02575a article EN Journal of Materials Chemistry B 2021-12-20

Deep eutectic solvents (DESs) and ionic liquids (ILs) are highly tailorable that have shown a lot of promise for variety applications including cryopreservation, drug delivery, protein stabilisation. However, to date, there is very limited information on the detailed interactions these with mammalian cells. In this work, we studied six DESs one IL show as cryoprotective agents, applying synchrotron macro–ATR–FTIR examine their effects key biochemical components HaCat These data were paired...

10.3390/biophysica3020021 article EN cc-by Biophysica 2023-05-04

Innovations in nanostructured surfaces have found a practical place the medical area with use implant materials for post-operative infection prevention. These textured should be dual purpose: 1)...

10.1039/d4nr03238a article EN Nanoscale 2024-12-16
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