A5072087598- Neuroscience and Neural Engineering
- Photoreceptor and optogenetics research
- EEG and Brain-Computer Interfaces
- Retinal and Macular Surgery
- Advanced Memory and Neural Computing
- Neural dynamics and brain function
- Conducting polymers and applications
- Hearing Loss and Rehabilitation
- Planarian Biology and Electrostimulation
- Bone Tissue Engineering Materials
- Tactile and Sensory Interactions
- Muscle activation and electromyography studies
- Advanced Optical Imaging Technologies
- Optical Coherence Tomography Applications
- Hearing, Cochlea, Tinnitus, Genetics
- Electrowetting and Microfluidic Technologies
- Ear Surgery and Otitis Media
- Ocular Surface and Contact Lens
- Neuroscience and Neuropharmacology Research
- CCD and CMOS Imaging Sensors
Seoul National University
2012-2019
Acetylcholine and noradrenaline are major neuromodulators that affect sensory processing in the cortex. Modality-specific information is processed defined areas of cortex, but it unclear whether cholinergic neurons basal forebrain (BF) noradrenergic locus ceruleus (LC) project to modulate these a modality-selective manner. Here, we mapped BF LC projections different cortices mouse using dual retrograde tracing. We found while innervation into predominantly modality specific, diverge onto...
term reliability of LCP-encapsulation was evaluated by an in vitro accelerated soak test, and possible failure mechanisms were investigated.The could provide reliable electrical insulation for ~400 days 75°C phosphate-buffered solution (PBS).
Liquid Crystal Polymer (LCP) has been considered as an alternative biomaterial for implantable biomedical devices primarily its low moisture absorption rate compared with conventional polymers such polyimide, parylene and silicone elastomers. A novel retinal prosthetic device based on monolithic encapsulation of LCP is being developed in which entire neural stimulation circuitries are integrated into a thin eye-conformable structure. Micromachining techniques fabrication electrode array have...
A polymer-based implantable stimulator for wirelessly navigating pigeons was conceptually suggested and a pilot study using depth electrodes conducted. In this study, based on liquid crystal polymer (LCP) with eight channels were designed fabricated. Electrochemical impedance spectrum (EIS) assessments performed to measure impedances of the electrodes. The average value measured 16.8∠15.8 ° kμ. then advanced target nucleus (formatio reticularis medialis mesencephalic, FRM) pigeon prove their...
(1) Background: In this study, we introduce a manufacturable 32-channel cochlear electrode array. contrast to conventional arrays manufactured by manual processes that consist of electrode-wire welding, the placement each electrode, and silicone molding over wired structures, proposed array is semi-automated laser micro-structuring mass-produced layer-by-layer deposition scheme similar semiconductor fabrication process. (2) Methods: The has 32 contacts with length 24 mm 0.75 spacing between...
To investigate the neuronal visual encoding process in retina, researchers have performed vitro and ex vivo electrophysiological experiments using animal retinal tissues. The microelectrode array (MEA) has become a key component because it enables simultaneous neural recording from population of neurons. However, most experiments, is inevitable that tissue flattened on planar MEA, becoming deformed original hemispherical shape. During deforming process, retina subjected to mechanical stress,...
Abstract The osseous regeneration of large bone defects is still a major clinical challenge in maxillofacial and orthopedic surgery. Our previous studies demonstrated that electrical stimulation (ES) with biphasic current pulse showed proliferative effects on cells enhanced secretion bone-forming growth factors. This study presents an implantable bioreactor electrodes based liquid crystal polymer (LCP), which has excellent bone-binding property. was implanted into critical sized defect...