In order to study the mechanisms underlying changes in mechanical properties of lungs during pulmonary edema, vascular congestion was produced spontaneously breathing, anesthetized dogs by partial aortic obstruction and intravenous infusion. Brief periods were associated with small lung compliance compared progressive striking reduction (-78%) noted more prolonged congestion. Lung volume at end-expiration showed little change if edema fluid trapped gas as well ventilated taken into account....

Eleven healthy, adult, male volunteers were exposed on separate occasions to average levels of sulfur dioxide 1, 5, and 13 ppm. The subjects seated in a body plethysmograph, breathing spontaneously by mouth while measurements respiratory mechanics made with an esophageal catheter. Exposures lasted 10–30 min and, for each subject, spaced at least 1 month apart. With one exception the group showed no significant increase pulmonary flow resistance lowest concentration gas. At both 5 ppm, was...

Sulfur dioxide35S (35SO2) was administered to the surgically isolated upper airways of anesthetized dogs via a mask with separate connections nose and mouth. The 35SO2 that passed through monitored continuously; nearly complete removal could be measured within several hundredths percent. Nasal uptake incoming gas (1 50 ppm) exceeded 99% at flow 3.5 liters/min fell only percent when increased tenfold (1, 10 ppm). Uptake by mouth averaged more than 95% but under 50% tenfold. Following...

In order to assess the effect of body position on esophageal pressure and pulmonary compliance, pressures were measured by means a ‘long’ thin-walled balloon at same lung volumes in different positions human subjects. Pulmonary compliance was relating change associated lung-volume change. The data indicate that supine false values may be obtained. These appeared caused an altered as result gravity pressing other mediastinal structures against esophagus. upright, lateral prone similar each...

Measurements of pulmonary compliance were made in 70 healthy young adults during interrupted breathing by the volume-step method. The values apply only to a volume range from 1.0–1.5 liters beginning at resting end-expiratory position, seated individuals. mean for group was 0.165±0.049 liters/cm water, with 0.09– 0.33 water. Within subject standard deviation repeated measurements single esophageal level ±0.015 water; combination two levels ±0.036 and obtained same on separate days ±0.019...

ABDOMINAL distention may cause dyspnea in patients without disease of the heart or lungs and aggravate with disease.* Reports measurements lung volumes pulmonary ventilation abdomen are characterized by variability methods, conditions study, results. Most previous observations were largely incidental often made on single cases.† The present study was undertaken to determine effects abdominal ascites ventilatory function, elucidate mechanisms which produces dyspnea, ascertain whether relief...

Among the forces that may contribute to first inflation of lungs after birth, those de- veloped through changes in pulmonary circu- latory system have been assigned primary impor- tance by Jaykka (1), Bonham Carter (2) and Adams, Karlberg Lind (3).Possibly ear- liest basis for this view was provided during last century von Basch (4) who showed ani- mals also experimental models pulmo- nary vascular congestion, presumably at capil- lary level, tends increase volume gas lungs.Recently, it...

On separate occasions, healthy male volunteers were exposed either by nose or mouth to one of two concentrations sulphur dioxide, 15 and 28 p.p.m. Exposure SO₂ lasted 10 minutes. Pulmonary flow resistance (R1) was measured the oesophageal catheter method, lung volume a modification gas-compression method; when administered nose, nasal (Rn) means placed in posterior pharynx. The increase R1 greater than it nose. Similarly, irritative symptoms pharynx chest more common during...

Comparison was made of essentially static volume-pressure relations the lobes excised dogs' lungs during stepwise deflation from a maximal distending pressure 30 cm H 2 O. No systematic differences were found among right apical, middle, and left apical nor between when gas volume expressed per unit tissue weight. However, mediastinal-lower lower held smaller volumes for any than did others. The small appear to play subordinate role in causing uneven ventilation typical healthy lungs. These...

The effects of acute reversible pulmonary vascular congestion on the elastic behavior excised cats' lungs were studied in 10 preparations. Measurements made changes airway pressure at constantly held lung volumes over a wide range deflation. To achieve left atrial was raised to 20 and 30 cm H 2 O. Two noted; one that slope volume-pressure relations slightly reduced all levels deflation, other, effect recoiling force function volume which induced. At large (airway pressures 5 O or more)...

Measurements were made of the effect pulmonary vascular distention on static volume-pressure relations excised cats' lungs filled either with saline to minimize surface forces, or inflated gas. Only slight changes questionable significance occurred in elastic behavior during deflation when pressure was increased from 0 16 cm H 2 O. also quasi-static at different lung volumes. The overall slope curve saline-filled greatest a moderate volume and slightly less collapsed highly distended....

Urinary tract infections (UTIs) are one of the most prevalent health issues in world during pregnancy. UTIs affect a large proportion women their reproductive years, especially underdeveloped nations. Women who pregnant more likely to acquire due number anatomical and hormonal changes. The effects on mother fetus numerous. This study determined prevalence factors associated with Tract Infections among attending ANC at Hoima regional referral hospital city, Western Uganda.This was based...

Blood 35S levels in anesthetized dogs rose progressively when the isolated upper airways were exposed to 35SO2 for 30 60 minutes, and decreased slightly hours following exposure. The plasma contained more than red blood cells (RBC); half of plasma-35S was dialyzable, greatest radioactivity among nondialyzable fraction being associated with α-globulin proteins. Two thirds RBC-35S appeared be intracellular. RBC-35S/Plasma-35S higher vivo exposure animals plasma- mixed nonradioactive RBC. Most...

Journal Article The Relation of Age to the Numbers Lung Free Cells, Weight, and Body Weight in Rats Get access Joseph D. Brain, Sc.D., Sc.D. Search for other works by this author on: Oxford Academic PubMed Google Scholar N. Robert Frank, M.D. 3North Wilmington, Massachusetts Gerontology, Volume 23, Issue 1, January 1968, Pages 58–62, https://doi.org/10.1093/geronj/23.1.58 Published: 01 1968

Takotsubo syndrome (TTS) is a cardiomyopathy that clinically presents as transient and reversible left ventricular wall motion abnormality (LVWMA). Recovery can occur spontaneously within hours or weeks. Studies have shown it mainly affects older people. In particular, there higher prevalence in postmenopausal women. Physical emotional stress factors are widely discussed generally recognized triggers. addition, the hypothalamic-pituitary-adrenal (HPA) axis associated glucocorticoid-dependent...