- Advanced battery technologies research
- Epilepsy research and treatment
- Cerebrospinal fluid and hydrocephalus
- Neonatal and fetal brain pathology
- Electrocatalysts for Energy Conversion
- Genetics and Neurodevelopmental Disorders
- Complex Network Analysis Techniques
- Advanced Image Fusion Techniques
- Metabolism and Genetic Disorders
- Parvovirus B19 Infection Studies
- Inflammatory Bowel Disease
- Opinion Dynamics and Social Influence
- Spinal Dysraphism and Malformations
- Advanced Image Processing Techniques
- Text and Document Classification Technologies
- Histiocytic Disorders and Treatments
- Neurological diseases and metabolism
- Congenital heart defects research
- Electrolyte and hormonal disorders
- IoT and Edge/Fog Computing
- Artificial Intelligence in Games
- Sparse and Compressive Sensing Techniques
- Medical Imaging Techniques and Applications
- Viral-associated cancers and disorders
- ECG Monitoring and Analysis
Central South University
2025
China North Industries Group Corporation (China)
2025
University of Houston
2024
North China University of Technology
2023
National Tsing Hua University
2023
Children's Hospital of Fudan University
2015-2021
Boston Children's Hospital
2014
Objective: Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is the most common form of autoimmune in pediatric patients. In this study, we aimed to investigate clinical features and long-term outcomes patients with anti-NMDAR China. Methods: We conducted a retrospective study children (age range: 0-18 years) treated at Children's Hospital Fudan University between July 2015 November 2018. Demographic characteristics, features, treatment, were reviewed. Results: Thirty-four...
Thin-section magnetic resonance imaging (MRI) can provide higher resolution anatomical structures and more precise clinical information than thick-section images. However, thin-section MRI is not always available due to the cost issue. In multicenter retrospective studies, a large number of data are often in manner with different section thickness. The lack difference thickness bring considerable difficulties study based on image big data. this article, we introduce DeepVolume, two-step deep...
The proposed architecture leverages the strengths of both Convolutional Neural Network (CNN) and Bidirectional Long Short-Term (BLSTM) to create a robust model for temporal expression recognition in clinical texts. CNN component effectively captures morphological orthographic features at character level, which enriches semantic understanding complex medical terminologies that are often abbreviated or have unique suffixes prefixes. BLSTM excels capturing long-range dependencies text, is...
Mutations in tumor necrosis factor alpha-induced protein 3 (TNFAIP3), a key player the negative feedback regulation of nuclear factor-κB signaling, have recently been recognized as leading to early onset autoinflammatory and autoimmune syndrome. Here, we reported phenotypes infantile intractable inflammatory bowel disease (IBD) patients with TNFAIP3 mutations reviewed previously cases establish phenotypic features associated monogenicity.From January 1, 2015, December 31, 2017, recruited 58...
Fe‐N‐C catalyst is acknowledged as a promising alternative for the state‐of‐the‐art Pt/C in oxygen reduction reaction (ORR) towards cutting‐edge electrochemical energy conversion/storage applications. Herein, "Cl‐mediation" strategy proposed on modulating catalyst's electronic structure achieving remarkable ORR activity. By coordinating axial‐Cl atoms to iron phthalocyanine (FePc) molecules carbon nanotubes (CNTs) matrix, Cl‐modulated (FePc‐Cl‐CNTs) synthesized. The as‐prepared FePc‐Cl‐CNTs...
Fe‐N‐C catalyst is acknowledged as a promising alternative for the state‐of‐the‐art Pt/C in oxygen reduction reaction (ORR) towards cutting‐edge electrochemical energy conversion/storage applications. Herein, "Cl‐mediation" strategy proposed on modulating catalyst's electronic structure achieving remarkable ORR activity. By coordinating axial‐Cl atoms to iron phthalocyanine (FePc) molecules carbon nanotubes (CNTs) matrix, Cl‐modulated (FePc‐Cl‐CNTs) synthesized. The as‐prepared FePc‐Cl‐CNTs...
Due to their high spatial resolution, thin-section magnetic resonance (MR) images serve as ideal medical for brain structure investigation and surgery navigation. However, compared with the clinically widely used thick-section MR images, are less available due imaging cost. Thin-section of infants even scarcer but quite valuable study human development. Therefore, we propose a method reconstruction from images. A two-stage framework based on generative adversarial networks (GANs)...
SHANK3 deficiency represents one of the most replicated monogenic risk factors for autism spectrum disorder (ASD) and caused ASD presents a unique opportunity to understand underlying neuropathological mechanisms ASD. In this study, genetic tests, comprehensive clinical neurobehavioral evaluations, as well multimodal structural MRI using voxel-based morphometry (VBM) tract-based spatial statistics (TBSS) were conducted in group (N = 14 with defects), controls 26 idiopathic without defects)...
Acute bilirubin encephalopathy or kernicterus is the worst consequence of brain damage caused by elevation total unbound serum (TSB) in neonates. The present study aimed to visualize characteristic regions neonates with hyperbilirubinemia (HB) using functional magnetic resonance imaging (fMRI) and measure amplitude low-frequency fluctuation (ALFF) values.This was a prospective cohort study, which included newborns HB who were hospitalized at Children's Hospital Fudan University. control...
The diagnosis of brain cancer relies heavily on medical imaging techniques, with MRI being the most commonly used. It is necessary to perform automatic segmentation tumors images. This project intends build an algorithm based U-Net. residual network and module used enhance context information are combined, void space convolution pooling pyramid added for processing. glioma image dataset provided by archives was experimentally verified. A multi-scale method a weighted least squares filter...
Heart rate arrhythmia is an important manifestation of common clinical cardiovascular diseases, posing a serious threat to human life and health. Due its suddenness, insidiousness rapid changes, it often causes patients miss the best treatment time. Therefore, real-time monitoring heart changes particularly monitor prevent onset such diseases. Nonetheless, information in telemedicine systems presented plaintext, rendering vulnerable interception or tampering, substantial users' privacy. To...
Objective To discuss our experience and efficacy of modified hemispherotomy for the treatment refractory epilepsy secondary to cerebral hemispheric disorders in children. Methods From September 2015 June 2016, a series 5 patients with intractable underwent at Neurosurgery Department Children’s Hospital Fudan University were enrolled into this retrospective study. None had atrophy or enlarged ventricles. Their ages surgery ranged from 8 months years. The left hemisphere was involved 3...
Objective To investigate the clinical and radiological features of children with first attack inflammatory central nervous system disorders seropositivity to myelin-oligodendrocyte glycoprotein (MOG). Methods The course, cerebrospinal fluid (CSF), MRI studies, MOG status outcomes were retrospectively analyzed in who hospitalized Children′s Hospital Fudan University from January 2016 April 2017. Results Thirteen patients including 8 males 5 females included this study, ratio...
Objective: To summarize the clinical and genetic features of β-propeller protein-associated neurodegeneration (BPAN). Methods: The data 17 patients with BPAN WDR45 gene variants were retrospectively collected at Children's Hospital Fudan University, Peking University First Hospital, Capital Institute Pediatrics, Shengjing China Medical Shanghai from June 2016 to December 2018, their manifestations, electroencephalogram, neuroimaging genetics analyzed. Results: Seventeen cases (13 females, 4...