A5076086980- Antibiotic Resistance in Bacteria
- Vibrio bacteria research studies
- Enterobacteriaceae and Cronobacter Research
- Salmonella and Campylobacter epidemiology
- Antibiotics Pharmacokinetics and Efficacy
- Pharmaceutical and Antibiotic Environmental Impacts
- Bacterial biofilms and quorum sensing
- Probiotics and Fermented Foods
- Aquaculture disease management and microbiota
- Plant-Microbe Interactions and Immunity
- Bacterial Genetics and Biotechnology
- Plant Pathogens and Resistance
- Cystic Fibrosis Research Advances
- Gut microbiota and health
- Autophagy in Disease and Therapy
- Plant Pathogens and Fungal Diseases
Queen's University Belfast
2016-2025
Washington University in St. Louis
2023-2024
University of Missouri–St. Louis
2024
City College
2023
City College of New York
2021-2023
City University of New York
2023
Instituto de Biología Molecular y Celular de Rosario
2017
Consejo Nacional de Investigaciones Científicas y Técnicas
2017
National University of Rosario
2017
Summary Reactive oxygen species ( ROS ) play fundamental roles in plant responses to pathogen infection, including modulation of cell death processes and defense‐related gene expression. Cell triggered as part the hypersensitive response enhances resistance biotrophic pathogens, but favors virulence necrotrophs. Even though involvement orchestration defense is well established, relative contribution specific subcellular sources against microorganisms with different pathogenesis strategies...
Background The Enterobacter cloacae complex (Ecc) encompasses opportunistic Gram-negative bacteria demonstrating considerable phenotypic and genotypic diversity. Bloodstream, respiratory urinary tract infections by Ecc are associated with morbidity mortality worldwide. These often difficult to treat since resistant penicillins, quinolones, aminoglycosides, third-generation cephalosporins. Resistance also extends carbapenems, leaving only polymyxins, such as colistin, a last resort antibiotic...
Enterobacter species are opportunistic, multidrug resistant Gram-negative bacteria associated with morbidity and mortality worldwide. Since very little is known about the infection biology of spp., we investigated intracellular trafficking a subset clinical isolates, including colistin-resistant strains, within human macrophages, determined macrophage response to infection. Phagocytosis 11 isolates representing E. cloacae, bugandensis, kobei, xiangfangensis, roggenkampii, hoffmannii,...
Abstract The gram-negative bacterium Vibrio cholerae is the causative agent of diarrhoeal disease cholera and responsible for seven recorded pandemics. Several factors are postulated to have led decline 6th pandemic classical strains rise El Tor biotype V. , establishing current 7th pandemic. We investigated ability 2nd pandemics engage their type six secretion system (T6SS) in microbial competition against non-pandemic strains. report that underwent sequential mutations T6SS genetic...
Acinetobacter baumannii is a multidrug-resistant opportunistic pathogen that persists in the hospital environment and causes various clinical infections, primarily affecting immunocompromised patients. A. has evolved wide range of mechanisms to compete with neighbouring bacteria. One such competition strategy depends on small secreted peptides called microcins, which exert antimicrobial effects contact-independent manner. Here, we report ATCC 17978 (AB17978) encodes class II microcin 17 978...
causes life-threatening infections that are becoming difficult to treat due increasing rates of multi-drug resistance (MDR) among clinical isolates. This has led the World Health Organization and CDC categorize MDR
Acinetobacter baumannii causes life-threatening infections that are becoming difficult to treat due increasing rates of multi-drug resistance (MDR) among clinical isolates. This has led the World Health Organization and CDC categorize MDR A . as a top priority for research development new antibiotics. Colistin is last-resort antibiotic carbapenem-resistant Not surprisingly, reintroduction colistin resulted in emergence colistin-resistant strains. Diclofenac nonsteroidal anti-inflammatory...
The Enterobacter cloacae complex (Ecc) is a group of enteric Gram-negative bacteria that also exist as commensals in nature. Ecc are responsible for nosocomial outbreaks, targeting primarily immunocompromised patients and causing wide range systemic infections. Infection often fatal management complicated by the high-level multidrug resistance expressed isolates. Indeed, species represent last ‘E’ ESKAPE pathogens, which global leading causes Despite clinical relevance Ecc, little known...
Burkholderia cenocepacia (Bc) is an environmental opportunistic pathogen that causes persistent, often severe, lung infections in individuals with cystic fibrosis and other underlying diseases. Rho GTPases are central molecular switches regulate cytoskeletal dynamics, trafficking, immune responses cell proliferation eukaryotic cells. Many microbes produce proteins target GTPase signalling. Bc employs a type VI secretion system (T6SS) to survive macrophages by disarming causing actin defects....