- Infectious Aortic and Vascular Conditions
- Aortic aneurysm repair treatments
- Aortic Disease and Treatment Approaches
- Peripheral Artery Disease Management
- ZnO doping and properties
- Cardiac Valve Diseases and Treatments
- Diagnosis and Treatment of Venous Diseases
- Venous Thromboembolism Diagnosis and Management
- Electrospun Nanofibers in Biomedical Applications
- Gas Sensing Nanomaterials and Sensors
- Vascular Procedures and Complications
- Copper-based nanomaterials and applications
- Orthopedic Surgery and Rehabilitation
- Consumer Behavior in Brand Consumption and Identification
- Cardiac and Coronary Surgery Techniques
- Medical and Biological Sciences
- Engineering Technology and Methodologies
- Advanced Theoretical and Applied Studies in Material Sciences and Geometry
- Transition Metal Oxide Nanomaterials
- Semiconductor materials and devices
- Coronary Interventions and Diagnostics
- Photonic Crystals and Applications
- Chalcogenide Semiconductor Thin Films
- Vascular anomalies and interventions
- Photonic and Optical Devices
Bulgarian Academy of Sciences
2012-2024
Medical University of Varna
2006-2020
University of Economics Varna
2013-2020
Science Research Laboratory
2018-2019
Université Laval
1997
Rationale: Prosthetic heart valves designed to be implanted percutaneously must loaded within delivery catheters whose diameter can as low 18 F (6 mm). This mandatory crimping of the devices may result in deleterious damages tissues used for valve manufacturing. As bovine and porcine pericardial tissue are currently given preference because their excellent availability traceability, a preliminary comparative study was undertaken highlight potential advantages. Materials methods: Bovine...
The intraluminal elastase perfusion model has been proved to be potentially effective in producing abdominal aortic aneurysm rodents, but it produced unpredictable results larger animals. purpose of this study was explore the potential ability such a produce experimental consistently Yucatán miniature swine. Six swine received infusion with porcine into an isolated segment infrarenal aorta. excised arterial segments were examined macroscopically assess luminal surface characteristics and...
A versatile electrospray method was utilized for deposition of thin ZnO films doped with Co (5%) (CZO) or co-doped (2.5%) and Al (CAZO). Thin polycrystalline approximate thickness 200 nm high transmittance (more than 80%) were obtained. No additional XRD peaks due to dopant impurities oxides observed. The cobalt doping led decrease in grain size increase crystallite from 22 29 the (101) direction. Smaller changes observed CAZO films. Surface roughness measured using a 3D optical profiler. 5...
Purpose:To validate the deployment, in vivo performance, biostability, and healing capacity of Anaconda self-expanding endoprosthesis a canine aortic aneurysm model. Methods:Aneurysms were surgically created 12 dogs by sewing woven polyester patch onto anterior side thoracic or abdominal aorta. prostheses implanted transfemorally for prescheduled periods (1 3 months). Aneurysm exclusion stent-graft patency monitored angiographically. Healing was assessed with histological analysis scanning...
Family plays a primary role in the demand formation consumer markets worldwide.It is field where wide variety of decisions are made every day.Family decisionmaking complex process which multiple individuals combine their personal needs, wants and resources order to reach satisfactory outcome.The development social system leads modifications known behavioral patterns family as consumption unit.This paper aimed at present-day Bulgarian marital structure.The distribution roles between spouses...
This study focuses on the influence of electrospray deposition parameters morphology, topography, optical and sensing properties ZnO films deposited gold electrodes quartz crystal resonators. The substrate temperature, precursor feed rate emitter’s voltage were varied. Zinc acetate dehydrate dissolved in a mixture deionized water, ethanol acetic acid was used as precursor. surface morphology average roughness studied by scanning electron microscopy (SEM) 3D profilometry, respectively, while...
Polycrystalline ZnO thin films were prepared on silicon substrates using electrospray method with vertical setup. Water and ethanol used as solvents for zinc acetate dehydrate no postdeposition annealing was required formation of ZnO. The influence substrate temperature in the range 150–250°C surface morphology roughness studied by Scanning Electron Microscopy (SEM), Atomic Force (AFM), optical profilometry. An improvement quality smoothing obtained. X-ray diffraction measurements revealed...
Sixty-two explanted Liotta porcine bioprostheses were examined to review the issues related their biocompatibility, biofunctionality, and biodurability. These harvested from 56 patients with implantation times ranging only a few hours more than nine years of implantation. There 10 acute short-term (< 1 year), 20 midterm (1 < t 5 years), 32 long-term (> years) cases. The indications for reoperations were: hemodynamic (59), thrombosis (10), endocarditis (3). major varied according duration...
Severely angulated (> 60°) or short (< 15mm) proximal necks remain significant anatomical limitations for endovascular stent-graft repairs abdominal aortic aneurysms. Ensuring proper fixation of the to host artery without short-or long-term risks endoleak migration represents a particular technical challenge these circumstances. An innovative balloon expandable stent combined with weft-knitted prosthesis was specifically designed situations by modelling neck anatomy overdistension potential...
Numerous endovascular stent grafts to treat intrarenal aortic aneurysms are now commercially available, and many new concepts currently in development worldwide. In order objectively quantify their outcomes, we propose a detailed protocol examine reference device that was harvested from patient who died few hours after stent-graft deployment for an abdominal aneurysm according the 3Bs rule (biocompatibility, biofunctionality, biodurability). Relevant history of this 63-year-old man included...
Twenty-nine modular stent-grafts deployed transrenally to repair AAAs with short necks in dogs were harvested at autopsy of the animals after scheduled durations implantations 10 days, one month, three months, and six months. Analyses explanted devices included non-destructive techniques such as gross observations, X-rays CT scan, IVUS angioscopy. Further appropriate dissection, histological investigations carried out by means scanning electron microscopy (SEM) light microscopy. All 29...
Further to the rapid enlargement of an aneurysm 5.6 cm in diameter after 3 years surveillance, a 79-year-old patient was fitted with Vanguard modular stent graft and monitored on regular basis for 6 years. Two later, aneurysmal sac ruptured. The died 1 month open surgery. device devoid any encapsulation ipsilateral limb detached from body. Nitinol skeleton mostly maintained, however, some polypropylene sutures were broken. resulting motion sharp-angled wires caused abrasion resulted few...
Six Talent stent-grafts were harvested at reoperations (N=5) and autopsy (N=1). The explants observed nondestructively, including gross morphology, X-rays, CT scans closed pressure system analysis. Nitinol frames in three devices another intact. One had a stent fracture of the proximal bare stent, one wire thin external supporting as well hole fabric just above bifurcation. For structurally intact, performed for type 1A endoleak (one patient) aorto-enteric fistulas (two patients). healing...
Using the retrieved devices from one autopsy and five reoperations, biocompatibility of explanted Talent stent-grafts was investigated to highlight capacity fabric act as an effective scaffold regenerate a blood conduit. The device encapsulated both internally externally, but capsules did not penetrate through structure. reoperation showed discrete patches compact fibrin irregularly scattered mural thrombi. Positive staining α-actin, tissue plasminogen activator (tPA), urokinase (uPA),...