Sarah Schütz

ORCID: 0009-0009-8679-3059
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About
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Research Areas
  • Infrared Thermography in Medicine
  • Immune cells in cancer
  • Cancer therapeutics and mechanisms
  • Dental Implant Techniques and Outcomes
  • Bone Tissue Engineering Materials
  • Cell death mechanisms and regulation
  • Cancer Mechanisms and Therapy
  • Phagocytosis and Immune Regulation

University Hospital of Basel
2024

University of Basel
2012-2024

Abstract Resistance to chemotherapy and PARPi inhibitors remains a critical challenge in the treatment of epithelial ovarian cancer, mainly due disabled apoptotic responses tumor cells. Given mesothelin’s pivotal role cancer its restricted expression healthy tissues, we conducted drug-screening discovery analysis across range genetically modified cells unveil therapeutic impact. We observed enhanced cell death with low mesothelin when exposed second mitochondria-derived activator caspases...

10.1101/2024.01.24.576987 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-01-26
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