David Espie

ORCID: 0009-0009-9074-6511
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About
Contact & Profiles
Research Areas
  • CAR-T cell therapy research
  • Nanowire Synthesis and Applications
  • Virus-based gene therapy research
  • Viral Infectious Diseases and Gene Expression in Insects
  • Antifungal resistance and susceptibility
  • Biomedical and Engineering Education
  • Semiconductor materials and devices
  • T-cell and B-cell Immunology

Institut Cochin
2022-2023

Université Paris Cité
2022-2023

Inserm
2022-2023

Centre National de la Recherche Scientifique
2022-2023

Paris Biotech Santé
2022

Aspergillus fumigatus is a ubiquitous mold that can cause severe infections in immunocompromised patients, typically manifesting as invasive pulmonary aspergillosis (IPA). Adaptive and innate immune cells respond to A. are present the endogenous repertoire of patients with IPA but infrequent cannot be consistently isolated expanded for adoptive immunotherapy. Therefore, we gene-engineered –specific chimeric antigen receptor (Af-CAR) T demonstrate their ability confer antifungal reactivity...

10.1126/scitranslmed.abh1209 article EN Science Translational Medicine 2022-09-28
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