Clarissa A. Borges

ORCID: 0000-0001-5013-2069
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About
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Research Areas
  • Escherichia coli research studies
  • Salmonella and Campylobacter epidemiology
  • Antibiotic Resistance in Bacteria
  • Viral gastroenteritis research and epidemiology
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Probiotics and Fermented Foods
  • Enterobacteriaceae and Cronobacter Research
  • Urinary Tract Infections Management
  • Listeria monocytogenes in Food Safety
  • Antimicrobial agents and applications
  • Vibrio bacteria research studies
  • Bacterial Identification and Susceptibility Testing
  • Identification and Quantification in Food
  • Cassava research and cyanide
  • Molecular Biology Techniques and Applications
  • Molecular Junctions and Nanostructures
  • Health Education and Validation
  • Parasites and Host Interactions
  • Pediatric health and respiratory diseases
  • Microbial infections and disease research
  • Neonatal Health and Biochemistry
  • Advanced biosensing and bioanalysis techniques
  • Synthesis and biological activity
  • Gut microbiota and health
  • Bacterial biofilms and quorum sensing

Universidade Estadual Paulista (Unesp)
2012-2022

University of California, Berkeley
2017-2022

Berkeley College
2018-2020

University of California System
2018

Universidade Federal de Uberlândia
2009

Escherichia coli recovered from poultry, and extraintestinal pathogenic E. (ExPEC), responsible for most cases of urinary tract infection (UTI) bloodstream (BSI) in humans, may share genetic characteristics, suggesting that poultry are a potential source ExPEC. Here, we compared isolated commercial broiler backyard chickens (n = 111) with ExPEC patients community- or hospital-acquired UTI BSI 149) Southeast Brazil. Isolates were genotyped by multilocus sequence typing, tested susceptibility...

10.1089/fpd.2019.2680 article EN Foodborne Pathogens and Disease 2019-08-14

Shigatoxigenic and enteropathogenic Escherichia coli with virulence multidrug resistance profile were isolated from Nile tilapia. This study finding is of great importance to public health because they help understand this pathogen epidemiology in fish demonstrate how these animals can transmit E. related diseases humans.

10.1016/j.bjm.2018.02.013 article EN cc-by-nc-nd Brazilian Journal of Microbiology 2018-05-21

Escherichia coli is a pathogen of major importance in swine and public health. To determine the prevalence Shiga toxigenic E. (STEC) enteropathogenic (EPEC), samples were collected from feces carcasses swines. In total, 441 four samplings, which 141 tested positive for either stx1, stx2, and/or eae genes. From samples, one STEC 15 atypical EPEC (aEPEC) isolates obtained, all originated same sampling. addition to eae, lpfA(O157/OI-141), ehxA, toxB, lpfA(O113) present aEPEC isolates. The only...

10.1089/fpd.2012.1206 article EN Foodborne Pathogens and Disease 2012-11-27

Trimethoprim is one of the most widely used antibiotics in world. However, its efficacy frequently limited by poor water solubility and dose limiting toxicity. Prodrug strategies based on conjugation oligosaccharides to trimethoprim have great potential for increasing lowering toxicity, but they been challenging develop due sensitivity chemical modifications, rapid degradation serum. In this report, we present a conjugate maltodextrin termed TM-TMP, which increased over 100 times, was stable...

10.1021/acs.bioconjchem.8b00177 article EN Bioconjugate Chemistry 2018-04-16

Pyometra is recognized as one of the main causes disease and death in bitch, Escherichia coli major pathogen associated with this disease. In study, 70 E. isolates from uteri horn, mouth, rectum bitches suffering 43 clinically healthy were examined for presence uropathogenic virulence genes susceptibility to antimicrobial drugs. DNA profiles horn mouth pyometra compared by REP, ERIC, BOX-PCR. Virulence gene frequencies detected canine follows: 95.7% fim , 27.1% iss 25.7% hly 18.5% iuc 17.1%...

10.1155/2014/979584 article EN cc-by International Journal of Microbiology 2014-01-01

Wild birds are carriers of Escherichia coli. However, little is known about their role as reservoirs for extra-intestinal pathogenic E. coli (ExPEC). In this work we investigated strains carrying virulence genes related to human and animal ExPEC isolated from free-living wild treated in a veterinary hospital. Multidrug resistance was found 47.4% the strains, but none them were extended-spectrum beta-lactamase producers. Not only genes, also serogroups (e.g. O1 O2) detected isolates have...

10.1080/03079457.2016.1209298 article EN Avian Pathology 2016-10-18

Reduction sensitive linkers (RSLs) have the potential to transform field of drug delivery due their ease use and selective cleavage in intracellular environments.

10.1039/d0sc00929f article EN cc-by-nc Chemical Science 2020-01-01

Avian pathogenic Escherichiacoli (APEC) virulence mechanism has been continuously studied and it is believed to be multifactorial because of this, this work aimed characterize potentially APEC strains isolated from free-range hens. Isolates were submitted PCR for the detection genes, which high prevalence. In vivo inoculation day-old chicks revealed that 49 these intermediate pathogenicity. addition, isolates antimicrobials susceptibility test with majority presenting multiresistance....

10.1590/1806-9061-2018-0876 article EN cc-by Brazilian Journal of Poultry Science 2019-01-01

The objective of this study was to describe the occurrence intestinal parasites inside public restrooms and buses from a Brazilian city. Sample material obtained using transparent adhesive tape. Thirty two were investigated (6.25%) contaminated with helminth eggs (Ascaris lumbricoides Enterobius vermicularis). Of sixteen different bus lines, three (18.7%) found harbor E. vermicularis. Public can be an important source parasite transmission sanitary education could improved by these points.

10.1590/s0036-46652009000400009 article EN Revista do Instituto de Medicina Tropical de São Paulo 2009-08-01

ABSTRACT: Avian pathogenic Escherichia coli (APEC) strains are isolated from lesions of poultry presenting colibacillosis, which is a disease that causes either systemic or localized clinical signs. Such share many characteristics with E. cause extra-intestinal illness in humans. There not consensus on how to define the APEC pathotype regard presence virulence traits. On other hand, past few years, five minimal predictors for detection were proposed. The isolates this work tested through...

10.1590/1808-1657000392014 article EN cc-by Arquivos do Instituto Biológico 2016-01-01

Antimicrobial resistance in urinary tract infections (UTIs) is a major public health concern. This study aims to characterize the phenotypic and genetic basis of multidrug (MDR) among expanded-spectrum cephalosporin-resistant (ESCR) uropathogenic Escherichia coli (UPEC) causing UTIs California patient populations. Between February October 2019, 577 ESCR UPEC isolates were collected from patients at 6 clinical laboratory sites across California. Lineage antibiotic genes determined by analysis...

10.1128/msphere.00471-22 article EN cc-by mSphere 2022-11-15

Extended-spectrum β-lactamase (ESBL)-producing Gram-negative bacteria (GNB) are increasingly identified as the cause of both community and healthcare-associated urinary tract infections (UTIs), with CTX-Ms being most common ESBLs identified. CTX-M-producing GNB resistant to β-lactam antibiotics frequently multidrug-resistant, which limits treatment options. Rapid diagnostic tests that can detect ESBL-producing GNB, particularly CTX-M producers, in urine patients UTIs needed. Results from...

10.1089/mdr.2020.0128 article EN Microbial Drug Resistance 2020-08-24

The development of antibiotics against Gram-negative bacteria is a central problem in drug discovery.

10.1039/c8me00011e article EN Molecular Systems Design & Engineering 2018-01-01

The microbiological quality of the ingredients used in feed production is extremely important for animal and public health because food can transmit pathogens. Chemical additives, such as Salmex®, may be to control these pathogens, since many sporulated microorganisms are resistant conventional heat treatment. For reasons, through bacteriological methods, this study evaluated presence pathogens meal tests efficiency additives combat highly microorganisms. Of 180 samples analyzed, 71 (39.4%)...

10.5897/ajmr12.185 article EN African Journal of Microbiology Research 2012-04-30

Livestock manure may contain pathogenic microorganisms which pose a risk to the health of animal or humans if is not adequately treated disposed of. To determine fate Shiga toxigenic Escherichia coli (STEC) non O157 in composted from naturally colonized sheep, fresh was obtained animals carrying bacterial cells with stx1/ stx2 genes. Two composting systems were used, aerated and non-aerated, experiments done Dracena city, São Paulo State. Every week, for seven weeks, one sample six different...

10.1590/1678-6001 article EN cc-by Arquivo Brasileiro de Medicina Veterinária e Zootecnia 2014-12-01

Abstract Enteropathogenic Escherichia coli (EPEC) is a pathogen associated with acute diarrhoea in humans. To determine whether EPEC isolated from healthy food‐producing animals possesses the same virulence gene repertoire as human diarrhoea, we compared six typical (tEPEC) and 20 atypical (aEPEC) humans 42 aEPEC (swine, sheep buffaloes), using pulsed‐field gel electrophoresis (PFGE), markers, serotyping subtyping of eae tir genes. We found that animal isolates shared genes, including nle B,...

10.1111/zph.13007 article EN Zoonoses and Public Health 2022-11-15

During processing of cattle carcasses, contamination may occurs with the transfer microbiota animals feaces to carcasses. This many times be byEscherichia coli carriers virulence factor as stx and eae genes being classified as Shiga like toxin. toxin-producing Escherichia coli (STEC) is recognized wordwide human pathogen. A survey was performed determine sensibility profile several antimicrobial drugs STEC in carcasses obtained from an abattoir Brazil between March 2008 and August at 2009. A...

10.5897/ajmr10.782 article EN African Journal of Microbiology Research 2011-08-01
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