Tyler J. Flanagan

ORCID: 0000-0001-5018-2189
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About
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Research Areas
  • High-Temperature Coating Behaviors
  • Metal and Thin Film Mechanics
  • Advanced materials and composites
  • Boron and Carbon Nanomaterials Research
  • Advanced biosensing and bioanalysis techniques
  • Aluminum Alloys Composites Properties
  • Tendon Structure and Treatment
  • Osteoarthritis Treatment and Mechanisms
  • Advanced ceramic materials synthesis
  • Supramolecular Self-Assembly in Materials
  • nanoparticles nucleation surface interactions
  • Microstructure and mechanical properties
  • Knee injuries and reconstruction techniques
  • Magnesium Alloys: Properties and Applications
  • Polymer Surface Interaction Studies
  • Metallic Glasses and Amorphous Alloys
  • Diamond and Carbon-based Materials Research

University of Connecticut
2018-2023

More than 32.5 million American adults suffer from osteoarthritis, and current treatments including pain medicines anti-inflammatory drugs only alleviate symptoms but do not cure the disease. Here, we have demonstrated that a biodegradable piezoelectric poly(L-lactic acid) (PLLA) nanofiber scaffold under applied force or joint load could act as battery-less electrical stimulator to promote chondrogenesis cartilage regeneration. The PLLA generated controllable charge, which promoted...

10.1126/scitranslmed.abi7282 article EN Science Translational Medicine 2022-01-12

Continuous nanolattices are an emerging class of mechanical metamaterials that highly attractive due to their superior strength-to-weight ratios, which originate from spatial architectures and nanoscale-sized elements possessing near-theoretical strength. Rational design frameworks remains challenging below 50 nm because limited methods arrange small into complex architectures. Here, we fabricate silica with ∼4- 20-nm-thick using self-assembly templating DNA origami perform in situ...

10.1016/j.xcrp.2023.101475 article EN cc-by Cell Reports Physical Science 2023-06-27

Magnesium is widely regarded as an excellent structural material, primarily because it forms the basis for a range of light-weight high-strength alloys. Recently, high-strain rate deformation magnesium has received great deal attention due to complicated modes that involve combinations dislocation slip and twinning. In this study, single crystal samples were shock-compressed along c- a-axis, then released back ambient conditions. Post-mortem transmission electron microscopy revealed...

10.1016/j.matdes.2020.108884 article EN cc-by-nc-nd Materials & Design 2020-06-13
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