A5062133177- Migration, Health and Trauma
- Healthcare cost, quality, practices
- Osteoarthritis Treatment and Mechanisms
- Tendon Structure and Treatment
- Pluripotent Stem Cells Research
- 3D Printing in Biomedical Research
- Disaster Response and Management
- Patient Safety and Medication Errors
- Knee injuries and reconstruction techniques
- COVID-19 epidemiological studies
- Renal Transplantation Outcomes and Treatments
- COVID-19 and healthcare impacts
- Palliative Care and End-of-Life Issues
- Additive Manufacturing and 3D Printing Technologies
- Ethics and Legal Issues in Pediatric Healthcare
- Wound Healing and Treatments
- Child and Adolescent Health
- Surgical Sutures and Adhesives
- Physical Activity and Health
- Bone Tissue Engineering Materials
- biodegradable polymer synthesis and properties
- Reconstructive Surgery and Microvascular Techniques
- Food Security and Health in Diverse Populations
- Cardiovascular Health and Risk Factors
- Vaccine Coverage and Hesitancy
UConn Health
2019-2022
University of Connecticut
2019-2021
California Institute for Regenerative Medicine
2019
Convergence
2019
Rutgers Cancer Institute of New Jersey
2012
More than 32.5 million American adults suffer from osteoarthritis, and current treatments including pain medicines anti-inflammatory drugs only alleviate symptoms but do not cure the disease. Here, we have demonstrated that a biodegradable piezoelectric poly(L-lactic acid) (PLLA) nanofiber scaffold under applied force or joint load could act as battery-less electrical stimulator to promote chondrogenesis cartilage regeneration. The PLLA generated controllable charge, which promoted...
Significance This paper describes a mechanically superior matrix that enhances the osteointegration and regeneration of ACL tissue in rabbit model. We show bone marrow aspirate concentrate presence cuboidal cells are reminiscent fibroblasts chondrocytes, sign enhanced regeneration. also demonstrates combinatorial application FGF-2 FGF-8 knee joint suppresses inflammation by reducing adipokine secretion. The incorporation nondegradable PET fibers into PLLA bioengineered showed improved...
Survivor care plans have been described as useful tools for enhancing the quality of follow-up that cancer survivors receive after their active treatment has completed. The relative success current survivor plan models is strongly dependent on actions individual patients. In this qualitative study 33 survivors, we explored patients' understanding and motivations resources seeking care. Three types experiences were identified from narratives patients treated in community oncology NCI...
In an effort to understand the biological capability of polyphosphazene-based polymers, three-dimensional biomimetic bone scaffolds were fabricated using blends poly[(glycine ethylglycinato)75(phenylphenoxy)25]phosphazene (PNGEGPhPh) and poly(lactic-co-glycolic acid) (PLGA), in vivo evaluation was performed a rabbit critical-sized defect model. The matrices constructed from PNGEGPhPh–PLGA surgically implanted into 15 mm radial defects rabbits as structural templates for tissue regeneration....
Abstract Acute traumatic nail injury treatment repair procedures are commonly conducted in emergency departments and primary care offices. Current methods use splints that inserted within the root to prevent fusion of proximal fold matrix tissue. Splints provide a protective barrier overlying bed soft tissue during recovery periods, but uncertain prognoses (i.e., aesthetic functional disadvantages) reveal need for improved techniques. Nail not specifically designed organ restoration via...
As African countries address the COVID-19 pandemic, we applaud continent and its efforts in crisis, offer a message that includes lessons learned from American experience.