- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Functional Brain Connectivity Studies
- MRI in cancer diagnosis
- Medical Image Segmentation Techniques
- Migraine and Headache Studies
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- COVID-19 and Mental Health
- Long-Term Effects of COVID-19
- Schizophrenia research and treatment
- Fetal and Pediatric Neurological Disorders
- Mental Health Research Topics
- Neurological disorders and treatments
- Tensor decomposition and applications
- Healthcare professionals’ stress and burnout
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Bone and Joint Diseases
- Glioma Diagnosis and Treatment
- Radiology practices and education
- Medical Imaging and Analysis
- Parkinson's Disease Mechanisms and Treatments
- Dental Radiography and Imaging
- NMR spectroscopy and applications
- Hip disorders and treatments
Universidad de Valladolid
2015-2024
IDEA Public Schools
2022
Hospital de Cruces
2020
Universidad de Salamanca
2020
Research Institute Hospital 12 de Octubre
2020
Hospital Santiago Apostol
2020
Instituto de Estudios de Ciencias de la Salud de Castilla y León
2020
Instituto de Investigación Biomédica de Salamanca
2018
Delft University of Technology
2017
Brigham and Women's Hospital
2010-2014
We studied the short-term psychological effects of COVID-19 crisis and quarantine on 3550 adults from Spanish population in a cross-sectional survey. Symptoms anxiety, depression, stress were analyzed using 21-item version Depression Anxiety Stress Scale. posttraumatic disorder Impact Event Symptomatic scores observed 20% to 30% respondents. indicating found 47.5% Similar findings other multiple studies, confinement has been have significant emotional impact population.
Abstract Background White matter alterations have been observed in patients with migraine. However, no microstructural white found particularly episodic or chronic migraine patients, and there is limited research focused on the comparison between these two groups of patients. Methods Fifty-one healthy controls, 55 57 were recruited underwent brain T1-weighted diffusion-weighted MRI acquisition. Using Tract-Based Spatial Statistics (TBSS), fractional anisotropy, mean diffusivity, radial...
The cingulum bundle (CB) connects gray matter structures of the limbic system and as such has been implicated in etiology schizophrenia. There is growing evidence to suggest that CB actually comprised a conglomeration discrete sub-connections. present study aimed use Diffusion Tensor tractography subdivide into its constituent sub-connections, investigate structural integrity these sub-connections patients with schizophrenia matched healthy controls. Imaging scans were acquired from 24...
Acquisition parameters play a crucial role in Diffusion Tensor Imaging (DTI), as they have major impact on the values of scalar measures such Fractional Anisotropy (FA) or Mean Diffusivity (MD) that are usually focus clinical studies based white matter analysis. This paper presents an analysis variation several acquisition these with novel double focus. First, tractography-based approach is employed, motivated by significant number carried out using this technique. Second, consequences...
Background: The outbreak and spread of a novel coronavirus disease (COVID-19) led to confinement situation in many countries worldwide. Our objective was analyze the short-term psychological effects COVID-19 crisis quarantine on population. Methods: A cross-sectional study conducted. survey completed by 3550 adults from Spain. Symptoms anxiety, depression stress were analyzed using 21-item version Depression Anxiety Stress Scale. posttraumatic disorder Impact Event Results: Symptomatic...
Headache is among the most frequently reported symptoms after resolution of COVID-19. We assessed structural brain changes using T1- and diffusion-weighted MRI processed data from 167 subjects: 40 patients who recovered COVID-19 but suffered persistent headache without prior history (COV), 41 healthy controls, 43 with episodic migraine chronic migraine. To evaluate gray matter white changes, morphometry parameters diffusion tensor imaging-based measures were employed, respectively. COV...
Objectives: Headache is a common symptom in systemic infections, and one of the symptoms novel coronavirus disease 2019 (COVID-19). The objective this study was to characterize phenotype COVID-19 headache via machine learning. Methods: We performed cross-sectional nested retrospective cohort. Hospitalized patients with confirmed diagnosis who described were included study. Generalized Linear Models Principal Component Analysis employed detect associations between intensity self-reported...
Background and Objective: Synthetic magnetic resonance imaging (MRI) is a low cost procedure that serves as bridge between qualitative quantitative MRI.However, the proposed methods require very specific sequences or private protocols which have scarcely found integration in clinical scanners.We propose learning-based approach to compute T1, T2, PD parametric maps from only pair of T1-and T2-weighted images customarily acquired routine.Methods: Our based on convolutional neural network (CNN)...
The term free-water volume fraction (FWVF) refers to the signal that could be found as cerebrospinal fluid of brain, which has been demonstrated a sensitive measure correlates with cognitive performance and various neuropathological processes. It can quantified by properly fitting isotropic component magnetic resonance (MR) in diffusion-sensitized sequences. Using N=287 healthy subjects (178F/109M) aged 25-94, this study examines detail evolution FWVF obtained spherical means technique from...
Abstract Our aim was to assess structural and functional networks in schizophrenia patients; the possible prediction of latter based on former. The dependence network properties alterations has not been analyzed schizophrenia. We applied averaged path‐length (PL), clustering coefficient, density (D) measurements data from diffusion magnetic resonance electroencephalography 39 patients 79 controls. Functional were collected for global theta frequency bands during an odd‐ball task, prior...
Spectral entropy (SE) allows comparing task-related modulation of electroencephalogram (EEG) between patients and controls, i.e. spectral changes the EEG associated to task performance. A SE deficit has been replicated in different schizophrenia samples. To investigate underpinnings deficits schizophrenia, we applied graph-theory recordings during a P300 fractional anisotropy (FA) data from diffusion tensor imaging 48 (23 first episodes) 87 healthy controls. Functional connectivity was...
Previous studies have demonstrated that emotional stress, changes in lifestyle habits and infections can worsen the clinical course of migraine. We hypothesize medical care during coronavirus disease 2019 (COVID-19) lockdown might worsened migraine.Retrospective survey study collecting online responses from migraine patients followed-up by neurologists at three tertiary hospitals between June July 2020.We used a web-based included demographic data, variables related with any headache...
To identify possible structural connectivity alterations in patients with episodic and chronic migraine using magnetic resonance imaging data.Fifty-four migraine, 56 50 controls underwent T1-weighted diffusion-weighted acquisitions. Number of streamlines (trajectories estimated fiber-tracts), mean fractional anisotropy, axial diffusivity radial were the connectome measures. Correlation analysis between measures duration frequency was performed.Higher lower number found connections involving...
To present a novel Optimized Diffusion-weighting Gradient waveform Design (ODGD) method for the design of minimum echo time (TE), bulk motion-compensated, and concomitant gradient (CG)-nulling waveforms diffusion MRI.ODGD motion-compensated were designed various moment-nullings Mn (n = 0, 1, 2), range b-values, spatial resolutions, both without (ODGD-Mn ) with CG-nulling -CG). Phantom in-vivo (brain liver) experiments conducted ODGD to compare motion robustness, signal-to-noise ratio (SNR),...
<h3>Background:</h3> The synchronized activity of distributed neural assemblies — reflected in the electroencephalogram (EEG) underpins mental function. In schizophrenia, modulation deficits EEG spectral content during a P300 task have been replicated. effects treatment, chronicity and specificity these their possible relationship with anatomic connectivity remain to be explored. <h3>Methods:</h3> We assessed entropy 79 patients schizophrenia (of those, 31 were first episode), 29 bipolar...