Margarita Rodríguez

ORCID: 0000-0002-7415-5908
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About
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Research Areas
  • Functional Brain Connectivity Studies
  • Advanced Neuroimaging Techniques and Applications
  • Cancer Genomics and Diagnostics
  • Lymphoma Diagnosis and Treatment
  • Migraine and Headache Studies
  • CAR-T cell therapy research
  • Glioma Diagnosis and Treatment
  • Gastrointestinal disorders and treatments
  • CNS Lymphoma Diagnosis and Treatment
  • Renal and Vascular Pathologies
  • Medical Imaging and Pathology Studies
  • Congenital Diaphragmatic Hernia Studies
  • Medical Imaging Techniques and Applications
  • Organ Donation and Transplantation
  • Pediatric Urology and Nephrology Studies
  • Advanced MRI Techniques and Applications
  • Ergonomics and Musculoskeletal Disorders
  • Prostate Cancer Treatment and Research
  • Robotic Mechanisms and Dynamics
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Cerebrospinal fluid and hydrocephalus
  • Mechanics and Biomechanics Studies
  • Pediatric Hepatobiliary Diseases and Treatments
  • Acute Ischemic Stroke Management
  • Archaeological Research and Protection

EIA University
2025

Hospital Universitario 12 De Octubre
2023-2024

Centro de Investigación Biomédica en Red de Cáncer
2023-2024

Universidad de Valladolid
2017-2023

Hospital Clínico Universitario de Valladolid
2014-2023

Universitat Politècnica de Catalunya
2015

Palmerston North Hospital
2015

Hospital Recoletas Campo Grande
2007

Purpose: To evaluate spontaneous eye blink rate (SEBR) and percentage of incomplete blinks in different hard-copy visual display terminal (VDT) reading conditions, compared with baseline conditions. Methods: A sample 50 participants (29 females, age range, 18–74 years) were recruited for this study. All had good ocular health reported no symptoms dry (OSDI score < 15). Face video recordings captured while observed silence a landscape picture at 2 m (baseline) during six different, 6-minute...

10.1167/iovs.15-16967 article EN Investigative Ophthalmology & Visual Science 2015-10-15

Abstract Background White matter alterations have been observed in patients with migraine. However, no microstructural white found particularly episodic or chronic migraine patients, and there is limited research focused on the comparison between these two groups of patients. Methods Fifty-one healthy controls, 55 57 were recruited underwent brain T1-weighted diffusion-weighted MRI acquisition. Using Tract-Based Spatial Statistics (TBSS), fractional anisotropy, mean diffusivity, radial...

10.1186/s10194-019-1071-3 article EN cc-by The Journal of Headache and Pain 2020-01-02

Headache is among the most frequently reported symptoms after resolution of COVID-19. We assessed structural brain changes using T1- and diffusion-weighted MRI processed data from 167 subjects: 40 patients who recovered COVID-19 but suffered persistent headache without prior history (COV), 41 healthy controls, 43 with episodic migraine chronic migraine. To evaluate gray matter white changes, morphometry parameters diffusion tensor imaging-based measures were employed, respectively. COV...

10.1007/s00415-022-11398-z article EN cc-by Journal of Neurology 2022-09-30

La diabetes se ha convertido en una enfermedad pública mundial que afecta la calidad de vida las personas y exige altos costos los sistemas salud. aumenta niveles glucosa sangre e induce el uso inadecuado insulina; tratamientos actuales no son muy eficaces para tratar esta enfermedad. En este estudio, desarrolló un andamio poroso alginato (Alg)/quitosano (Ch), reticulado con genipina (GEN), funcionalizado factor crecimiento endotelial (VEGF-A) mediante acoplamiento carbodiimida-Ch, soportar...

10.24050/reia.v22i43.1838 article ES cc-by-nc-nd Revista EIA 2025-01-01

To identify possible structural connectivity alterations in patients with episodic and chronic migraine using magnetic resonance imaging data.Fifty-four migraine, 56 50 controls underwent T1-weighted diffusion-weighted acquisitions. Number of streamlines (trajectories estimated fiber-tracts), mean fractional anisotropy, axial diffusivity radial were the connectome measures. Correlation analysis between measures duration frequency was performed.Higher lower number found connections involving...

10.1177/0333102419885392 article EN Cephalalgia 2019-11-01

Abstract Objective This study evaluates different parameters describing the gray matter structure to analyze differences between healthy controls, patients with episodic migraine, and chronic migraine. Design Cohort study. Setting Spanish community. Subjects Fifty-two 57 migraine patients, were included in underwent T1-weighted magnetic resonance imaging acquisition. Methods Eighty-four cortical subcortical regions extracted, volume, curvature, thickness, surface area values computed (where...

10.1093/pm/pnaa271 article EN Pain Medicine 2020-07-22

The white matter state in migraine has been investigated using diffusion tensor imaging (DTI) measures, but results this technique are conflicting. To overcome DTI we employed ensemble average propagator measures obtained with apparent reduced acquisitions (AMURA). AMURA were return-to-axis (RTAP), return-to-origin (RTOP) and return-to-plane probabilities (RTPP). Tract-based spatial statistics was used to compare fractional anisotropy, mean diffusivity, axial diffusivity radial from DTI,...

10.3390/brainsci10100711 article EN cc-by Brain Sciences 2020-10-06

Background CART therapy has produced a paradigm shift in the treatment of relapsing FL patients. Strategies to optimize disease surveillance after these therapies are increasingly necessary. This study explores potential value ctDNA monitoring with an innovative signature personalized trackable mutations. Method Eleven patients treated anti-CD19 CAR T-cell were included. One did not respond and was excluded. Genomic profiling performed before starting lymphodepleting chemotherapy identify...

10.3389/fimmu.2023.1188818 article EN cc-by Frontiers in Immunology 2023-06-05

Abstract No specific migraine biomarkers have been found in single‐modality MRI studies. We aimed at establishing for episodic and chronic using diverse modalities. employed canonical correlation analysis joint independent component to find structural connectivity abnormalities that are related gray matter morphometric alterations. The number of streamlines (trajectories estimated fiber‐tracts from tractography) was as measure, while cortical curvature, thickness, surface area, volume were...

10.1002/hbm.25267 article EN cc-by Human Brain Mapping 2020-12-08

This study discusses the importance of minimal residual disease (MRD) detection in acute myeloid leukemia (AML) patients using liquid biopsy and next-generation sequencing (NGS). AML prognosis is based on various factors, including genetic alterations. NGS has revealed molecular complexity helped refine risk stratification personalized therapies. The long-term survival rates for are low, MRD assessment crucial predicting prognosis. Currently, most common methods flow cytometry quantitative...

10.3389/fimmu.2024.1252258 article EN cc-by Frontiers in Immunology 2024-06-13
Lucía Pérez‐Lamas Adrián Segura Díaz Regina García Delgado Alberto Álvarez‐Larrán María Alicia Senin and 78 more Elvira Mora María Laura Fox Irene Pastor Galan Gemma Azaceta Sara Garrido Paniagua Raúl Pérez López Daniel Carvajal Anna Angona Carmen Albo Lopez Porto Alegre Míriam Vara Juan Antonio Juan Vera Goñi D. de Miguel Llorente Ángeles Fernández Rodríguez Alberto Marin Sanchez Adriana Hernando Megido María Teresa Gómez‐Casares Ruth Stuckey Gonzalo Carreño Natalia De Las Heras Rodríguez Blanca Xicoy Manuel Pérez‐Encinas Raquel Mata Serna Lucía Núñez Martín-Buitrago Francisca Ferrer‐Marín Neus Amer Salas Carolina Guillén Rienda Patricia Vélez Laura Lamarca Eraso Sandra Pérez Martín Iryna Luts Khoroz Erik de Cabo Ángela Gil Simone G. Ramos Fernando Marco De Lucas María José Otero Martínez-Fornes María Luisa Martín Mateos Teresa Arquero Esther Pérez Luis Antonio López Gómez Ángela Martínez Hellín Aurelia Tejedor Esther Herrera de Pablo Maria Isabel Mata Vazquez Inmaculada Castillo Valero María José Fernández Carlos Aguilar Marta Santaliestra Antonio Garcia Menchon Begoña Navas Elorza María Antonia Durán M Sala Teresa Hernández Santamaría Ma Ángeles Muñoz Jarreño Julio Dávila Wladimiro Jiménez Javier Fernández Hugo Alexander Torres Mantilla T. Rodrı́guez Aitor Abuín Blanco Francisco Javier Ridruejo Pérez María José Llácer Ferrandis Paola Beneit Villena Raisa Peralta Federico Herrera Eloi Cañamero Reyes Jiménez‐Bárcenas Mercedes Gasior Kabat Sonia González de Villambrosía Margarita Rodríguez Marina Menéndez Cuevas Beatriz Cuevas Ruiz Marta Fonseca Sandra Piquer Rosalía Delapuerta Álvaro Lorenzo Vizcaya Juan Carlos Hernández‐Boluda Valentín García‐Gutiérrez

10.1182/blood-2024-200698 article EN Blood 2024-11-05
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