A5071465818- Advanced Neuroimaging Techniques and Applications
- Migraine and Headache Studies
- Functional Brain Connectivity Studies
- Advanced MRI Techniques and Applications
- Long-Term Effects of COVID-19
- COVID-19 and Mental Health
- MRI in cancer diagnosis
- Mental Health Research Topics
- Psychosomatic Disorders and Their Treatments
- Epilepsy research and treatment
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Healthcare professionals’ stress and burnout
- Schizophrenia research and treatment
- Fetal and Pediatric Neurological Disorders
- Cerebral Venous Sinus Thrombosis
- Cardiovascular Syncope and Autonomic Disorders
- Trigeminal Neuralgia and Treatments
- Neurological Complications and Syndromes
- Resilience and Mental Health
- Olfactory and Sensory Function Studies
- Vestibular and auditory disorders
- Maternal Mental Health During Pregnancy and Postpartum
- Peripheral Nerve Disorders
- Heme Oxygenase-1 and Carbon Monoxide
- Pain Management and Treatment
Universidad de Valladolid
2019-2024
Cardiff University
2022-2024
Imagerie et Cerveau
2023
Headache is one of the most frequent neurologic manifestations in COVID-19. We aimed to analyze which symptoms and laboratory abnormalities were associated with presence headache evaluate if patients had a higher adjusted in-hospital risk mortality.Retrospective cohort study. included all consecutive admitted Hospital confirmed SARS-CoV-2 infection between March 8th April 11th, 2020. collected demographic data, clinical variables abnormalities. used multivariate regression analysis.During...
We studied the short-term psychological effects of COVID-19 crisis and quarantine on 3550 adults from Spanish population in a cross-sectional survey. Symptoms anxiety, depression, stress were analyzed using 21-item version Depression Anxiety Stress Scale. posttraumatic disorder Impact Event Symptomatic scores observed 20% to 30% respondents. indicating found 47.5% Similar findings other multiple studies, confinement has been have significant emotional impact population.
Abstract Background White matter alterations have been observed in patients with migraine. However, no microstructural white found particularly episodic or chronic migraine patients, and there is limited research focused on the comparison between these two groups of patients. Methods Fifty-one healthy controls, 55 57 were recruited underwent brain T1-weighted diffusion-weighted MRI acquisition. Using Tract-Based Spatial Statistics (TBSS), fractional anisotropy, mean diffusivity, radial...
Introduction Headache is a common symptom of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In this study, we aimed to characterize phenotype headache attributed SARS-CoV-2 infection and test International Classification Disorders (ICHD-3) phenotypic criteria for migraine tension-type headache. Methods The study design was cross-sectional nested in cohort. We screened all consecutive patients that were hospitalized had positive test. included described if not...
Background: The outbreak and spread of a novel coronavirus disease (COVID-19) led to confinement situation in many countries worldwide. Our objective was analyze the short-term psychological effects COVID-19 crisis quarantine on population. Methods: A cross-sectional study conducted. survey completed by 3550 adults from Spain. Symptoms anxiety, depression stress were analyzed using 21-item version Depression Anxiety Stress Scale. posttraumatic disorder Impact Event Results: Symptomatic...
Headache is among the most frequently reported symptoms after resolution of COVID-19. We assessed structural brain changes using T1- and diffusion-weighted MRI processed data from 167 subjects: 40 patients who recovered COVID-19 but suffered persistent headache without prior history (COV), 41 healthy controls, 43 with episodic migraine chronic migraine. To evaluate gray matter white changes, morphometry parameters diffusion tensor imaging-based measures were employed, respectively. COV...
Objectives: Headache is a common symptom in systemic infections, and one of the symptoms novel coronavirus disease 2019 (COVID-19). The objective this study was to characterize phenotype COVID-19 headache via machine learning. Methods: We performed cross-sectional nested retrospective cohort. Hospitalized patients with confirmed diagnosis who described were included study. Generalized Linear Models Principal Component Analysis employed detect associations between intensity self-reported...
Previous studies have demonstrated that emotional stress, changes in lifestyle habits and infections can worsen the clinical course of migraine. We hypothesize medical care during coronavirus disease 2019 (COVID-19) lockdown might worsened migraine.Retrospective survey study collecting online responses from migraine patients followed-up by neurologists at three tertiary hospitals between June July 2020.We used a web-based included demographic data, variables related with any headache...
To identify possible structural connectivity alterations in patients with episodic and chronic migraine using magnetic resonance imaging data.Fifty-four migraine, 56 50 controls underwent T1-weighted diffusion-weighted acquisitions. Number of streamlines (trajectories estimated fiber-tracts), mean fractional anisotropy, axial diffusivity radial were the connectome measures. Correlation analysis between measures duration frequency was performed.Higher lower number found connections involving...
Abstract Objective This study evaluates different parameters describing the gray matter structure to analyze differences between healthy controls, patients with episodic migraine, and chronic migraine. Design Cohort study. Setting Spanish community. Subjects Fifty-two 57 migraine patients, were included in underwent T1-weighted magnetic resonance imaging acquisition. Methods Eighty-four cortical subcortical regions extracted, volume, curvature, thickness, surface area values computed (where...
Diffusion-relaxation MRI aims to extract quantitative measures that characterise microstructural tissue properties such as orientation, size, and shape, but long acquisition times are typically required. This work proposes a physics-informed learning framework an optimal subset of diffusion-relaxation measurements for enabling shorter times, predict non-measured signals, estimate parameters. In vivo synthetic brain 5D-Diffusion-T
The aim of this study was to analyze the psychological impact COVID-19 in university community during first weeks confinement. A cross-sectional conducted. Depression Anxiety Stress Scale (DASS-21) employed assess symptoms depression, anxiety and stress. emotional situation analyzed using Impact Event Scale. An online survey fulfilled by 2530 members University Valladolid, Spain. Moderate extremely severe scores anxiety, stress were reported 21.34%, 34.19% 28.14% respondents, respectively....
Anomalous self-experiences (ASEs) in schizophrenia have been under research for the last 20 years. However, no neuroimage studies provided insight of possible biological underpinning ASEs. In this novel approach, connectivity within default mode network, calculated through a ROI-based analysis functional magnetic resonance imaging data, was correlated to ASEs scores assessed by Inventory Psychotic-Like Self-Experiences (IPASE) sample 22 patients. The Pearson's correlation coefficients...
The white matter state in migraine has been investigated using diffusion tensor imaging (DTI) measures, but results this technique are conflicting. To overcome DTI we employed ensemble average propagator measures obtained with apparent reduced acquisitions (AMURA). AMURA were return-to-axis (RTAP), return-to-origin (RTOP) and return-to-plane probabilities (RTPP). Tract-based spatial statistics was used to compare fractional anisotropy, mean diffusivity, axial diffusivity radial from DTI,...
The objective of this study is to evaluate the efficacy deep learning (DL) techniques in improving quality diffusion MRI (dMRI) data clinical applications. aims determine whether use artificial intelligence (AI) methods medical images may result loss critical information and/or appearance false information. To assess this, focus was on angular resolution dMRI and a trial conducted migraine, specifically between episodic chronic migraine patients. number gradient directions had an impact...
Neuroimaging has revealed that migraine is linked to alterations in both the structure and function of brain. However, relationship these changes with aging not been studied detail. Here we employ Brain Age framework analyze migraine, by building a machine-learning model predicts age from neuroimaging data. We hypothesize patients will exhibit an increased Gap (the difference between predicted chronological age) compared healthy participants.
Abstract To date, two randomized, controlled studies support the use of candesartan for migraine prophylaxis but with limited external validity. We aim to evaluate effectiveness and tolerability in clinical practice explore predictors patient response. Retrospective cohort study including all patients who received between April 2008-February 2019. The primary endpoint was number monthly headache days during weeks 8–12 treatment compared baseline. Additionally, we evaluated frequency 20–24....
Abstract No specific migraine biomarkers have been found in single‐modality MRI studies. We aimed at establishing for episodic and chronic using diverse modalities. employed canonical correlation analysis joint independent component to find structural connectivity abnormalities that are related gray matter morphometric alterations. The number of streamlines (trajectories estimated fiber‐tracts from tractography) was as measure, while cortical curvature, thickness, surface area, volume were...
Face-to-face procedures have been postponed during COVID-19 pandemic. We aim to evaluate the impact of onabotulinumtoxinA follow-up delay in migraine Subjective worsening, intensity attacks, and frequency headache were retrospectively compared between patients with unmodified interrupted Headache Units. included 67 chronic or high-frequency episodic under treatment, 65 (97.0%) female, 44.5 ± 12.1 years old. Treatment administration was voluntarily delayed 14 (20.9%) nine (13.4%) unable...
To evaluate the efficacy of a new visual training program for improving function in patients implanted with trifocal intraocular lenses (IOLs).Randomised placebo-controlled clinical trial enrolling 60 subjects (age, 47-75 years) undergoing cataract surgery implantation diffractive IOL. Home-based active was prescribed immediately after to all them (20 sessions, 30 min): 31 using serious game based on Gabor patches (study group) and 29 placebo software (placebo group). Visual acuity, contrast...