A5103045039- Land Use and Ecosystem Services
- Clostridium difficile and Clostridium perfringens research
- Mycotoxins in Agriculture and Food
- Flood Risk Assessment and Management
- Urban Heat Island Mitigation
- Microbial infections and disease research
- Urban Green Space and Health
- Insect and Pesticide Research
- Wildlife-Road Interactions and Conservation
- Urban Design and Spatial Analysis
- Urban Transport and Accessibility
- Radiopharmaceutical Chemistry and Applications
- Pesticide Residue Analysis and Safety
- Toxin Mechanisms and Immunotoxins
- Remote Sensing and Land Use
- Gut microbiota and health
- Impact of Light on Environment and Health
- Medical Imaging Techniques and Applications
- Remote Sensing and LiDAR Applications
- Wildlife Ecology and Conservation
- Advanced biosensing and bioanalysis techniques
- Viral gastroenteritis research and epidemiology
- Solar Radiation and Photovoltaics
- Microscopic Colitis
- Biosensors and Analytical Detection
Ministry of Agriculture and Rural Affairs
2024-2025
Southwest University
2023-2025
Queen Mary University of London
2024
University College London
2022-2024
University of Hong Kong
2024
Boston Children's Hospital
2024
Harvard University
2024
University of Liverpool
2024
Shanghai Tongji Urban Planning and Design Institute
2022-2023
Tongji University
2023
Urban flooding risks, often overlooked by conventional methods, can be profoundly affected city configurations. However, explainable Artificial Intelligence could provide insights into how urban configurations flooding. This study, taking entered on Shenzhen City, deploys an XGBoost, integrating SHapley Additive exPlanation and Partial Dependency Plots, to assess morphology influences susceptibility. The models strategies presented in this study aimed adapt extreme storms from the...
As an important indicator of urban development capacity, vitality can be affected by the human perception street views, which is a dynamic sensory process that differ greatly according to different transportation modes, due their travel speeds, distances, and routes. However, few studies have evaluated how spatial perceptions between modes these differences affect differently, limitation city-scale quantitative data on scenes. To fill gap, we propose “dynamic through-movement perception”...
This study presents a comprehensive methodology for the implementation of Nature-based Solutions (NbS) in context urban flood mitigation, specifically within heritage city Guangzhou, China. The investigation delves into roles morphology and impermeability exacerbating risk through enhanced runoff accumulation reduced infiltration. A key focus is spatial heterogeneity susceptibility, influenced by disparate distribution various building types demographic segments. research integrates...
(177)Lu-labeled ethylenediamine-N,N,N',N'-tetrakis methylene phosphonic acid ((177)Lu-EDTMP), was used to palliate metastatic bone pain as a new bone-seeking radiopharmaceutical. In this phase II study, we assessed the efficacy and safety of (177)Lu-EDTMP for palliation in patients with breast cancer hormone refractory prostate metastases.Sixteen were enrolled trial subsequently divided into 2 groups, low-dose group (1295 MBq) high dose (2590 determine differences toxicities response rates....
The G protein-coupled receptors of the Frizzled (FZD) family, in particular FZD1,2,7, are that exploited by Clostridioides difficile toxin B (TcdB), major virulence factor responsible for pathogenesis associated with infection. We employ a live-cell assay examining affinity between full-length FZDs and TcdB. Moreover, we present cryoelectron microscopy structures TcdB alone complex FZD7, which reveal large structural rearrangements combined repetitive polypeptide domain required interaction...
A lateral flow dual immunoassay (LFDIA) was developed for rapid quantitative detection of zearalenone (ZEN) and fumonisin B1 (FB1) in corn wheat samples on a single test strip. Two lines the control line nitrocellulose membrane were coated with ZEN FB1 conjugates goat anti-mouse IgG, respectively. Colloidal gold nanoparticles conjugated monoclonal antibodies against or FB1. The intensity analyzed by photometric strip reader to determine concentrations based calibration curves known versus...
Visual perception of the urban landscape in a city is complex and dynamic, it largely influenced by human vision dynamic spatial layout attractions. In return, visibility not only affects how people interact with environment but also promotes regional values resilience. The development has evolved, digital analysis method allows researchers to redefine visible space better quantify perceptions observations space. this paper, we first reviewed compared theoretical results measurement tools...
The indiscriminate evolution of urban configurations aggravates flood vulnerabilities, threatening sustainable expansion. Present methodologies fall short in supplying planners with mitigative strategies centered on configuration facets. Leveraging the power XGBoost algorithm, this study posits an advanced optimization schema, adroitly balancing dual objectives mitigating flooding and enhancing economic growth, minimal disruption to established layouts. Shenzhen serves as investigative...
The efficiency of the absorption and digestion lutein in infant formulas (IFs) is remarkably lower than that human milk. This work compared simulated vitro dynamic digestive characteristics three stages milk six IFs, with a special emphasis on how polar lipids affect digestion. Compared colostrum (CM), IF2 had significantly higher loss rate but micellarization bioaccessibility rates. In CM, morphology fat globules (MFGs) remained visible after digestion; phospholipid globular membrane...
A novel highly sensitive chemiluminescence immunoassay (CLIA) was developed to detect zearalenone in food samples by using both biotinylated conjugates and gold (Au) nanoparticles labeled with streptavidin–horseradish peroxidase for signal amplification. Biotinylated zearalenone–ovalbumin Au were synthesized separately. The concentrations of immunoreagents the reaction times these optimized improve performances analytical methods. For CLIA based on peroxidase, limit detection 0.008 ng/mL...
Human milk phospholipids are important for the regular growth and development of infants. Ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC/Q-TOF-MS) was employed to qualitatively quantitatively analyze 277 phospholipid molecular species in 112 human samples obtain a detailed profile along lactation stage. MS/MS fragmentation patterns sphingomyelin, phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol, phosphatidylserine were...
Concurrent meteorological extremes (CMEs) represent a class of pernicious climatic events characterized by the coexistence two extreme weather phenomena. Specifically, juxtaposition Urban Extreme Rainfall (UER) and Heat (UEH) can precipitate disproportionately deleterious impacts on both ecological systems human well-being. In this investigation, we embarked meticulous risk appraisal CMEs within China’s Greater Bay Area (GBA), harnessing predictive capabilities three shared socioeconomic...
Mycotoxins produced by different species of fungi may coexist in single cereal and feedstuff samples, which could become highly toxic for humans animals. In order to quantify four mycotoxins (zearalenone, fumonisin B1, deoxynivalenol, aflatoxin B1) samples simultaneously, a new suspension array immunoassay was developed. Antimycotoxin monoclonal antibodies were conjugated the surface encoding microspheres (19#, 37#, 39#, 49#), mycotoxin–protein conjugates then coupled with biotin. Using...
A hypotoxic immunosorbent assay for the detection of zearalenone (ZEN) was developed, by identifying a single-stranded DNA (ssDNA) aptamer with high specificity and affinity ZEN monoclonal antibody (mAb-ZEN). ssDNA aptamers, which could mimic epitopes, were identified using modified systematic evolution ligands an exponential enrichment (SELEX) technique. The purified mAb-ZEN coated on microtiter plates as target recognized random oligonucleotide library. binding between aptamers during each...
Abstract The morphological design of urban space affects the quality environment. traditional experience-based approach was greatly improved by introducing computational tools. However, existing tools are mostly developed on pre-set rules or given targets, which have few contributions to enhance creativity generate inspiring schemes. Therefore, this paper proposes a new named UDGAN, integrating generative adversarial networks (GANs) and multi-objective optimization algorithms. This model...