A5064534850- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- MicroRNA in disease regulation
- Extracellular vesicles in disease
- Peptidase Inhibition and Analysis
- Studies on Chitinases and Chitosanases
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Parasites and Host Interactions
- Nanocomposite Films for Food Packaging
- Immune Cell Function and Interaction
- Amoebic Infections and Treatments
- Galectins and Cancer Biology
- Dietary Effects on Health
- Neuropeptides and Animal Physiology
- Parasitic Infections and Diagnostics
- Mesenchymal stem cell research
- Immune cells in cancer
- Diabetes and associated disorders
- Leptospirosis research and findings
- Cell Adhesion Molecules Research
- Wound Healing and Treatments
- Diagnosis and treatment of tuberculosis
- Autoimmune and Inflammatory Disorders Research
- Genomics and Chromatin Dynamics
Shahid Beheshti University of Medical Sciences
2015-2024
University of Guilan
2022
Shahid Beheshti University
2011-2015
Babol University of Medical Sciences
2014
Charlottesville Medical Research
2014
Shiraz University of Medical Sciences
2003-2009
: Acinetobacter baumannii (A. baumannii) is an important opportunistic pathogen responsible for nosocomial infections worldwide at recent decades. Biofilm formation by A. leads to antibiotic resistance and survives on abiotic biotic surfaces. In the present study we aimed assess ability of biofilm in clinical environmental isolates phenotypic methods detect presence genes involving development; bap, ompA, csuE, abaI, blaPER-1by PCR method. Totally 120 baumanniin isolates, 98 clinical, 22...
Background: Intestinal parasites of humans are one the most important health problems worldwide, especially those located in tropical and subtropical areas. Objectives: The aim this study was to determine frequency intestinal patients with gastrointestinal disorders, different parts Iran. Patients Methods: A total 1520 stool samples were collected from disorders. specimens examined by direct wet mount, formalin-ether concentration a modified version Ziehl-Neelsen staining technique....
Background: Wound healing is a complex process.Different types of skin cells, extracellular matrix and variety growth factors are involved in wound healing.The use recombinant researches production substitutes still challenge.Objectives: Much research has been done on the effects gene therapy cell healing.In this experimental study, effect insulin-like factor (IGF-1) transfer fibroblast cells was assessed acute dermal healing.Materials Methods: Fibroblasts were cultured transfected with...
Polymorphisms in ctla-4 gene have been shown to be associated with the Graves' disease (GD) susceptibility different populations world. This study was undertaken disclose probable association of exon-1 polymorphism GD Iranian patients. A49G investigated 90 patients and age/sex matched normal healthy controls, using PCR-SSCP PCR-RFLP methods. Frequencies AA, AG GG genotypes among were found 21 (23.3%), 49 (54.5%) 20 (22.2%) while these frequencies controls 30 (33.3%), 53 (58.9%) 7(7.8%),...
Background and objectives: Development of a vaccine against leishmaniasis, which is able to induce protective immune responses, an important objective. The live non-pathogenic lizard parasites have recently provided promising new approach develop leishmaniasis.Methods: Four groups female BALB/c mice were examined in the study: group 1 received PBS, 2 CpG, 3 2×10 5 Iranian Lizard Leishmania (ILL) promastigotes 4 ILL mixed with CpG (ILL+CpG). All injections carried out subcutaneously right...
Background: We aimed to compare parasite burden in BALB/c mice, using three methods including the direct fluorescent microscopic recombinant Leishmania major expressing an enhanced green protein, limiting dilution assay, and real-time PCR technique. Methods: The current study was carried out 2018, induce stable protein (EGFP) production. Initially, linearized DNA expression cassette (pLEXSY-egfp-sat2) integrated into ssu locus of L. major. EGFP analyzed microscopy. Afterward, mice were...
Systemic lupus erythematosus (SLE) is a complex autoimmune disease which involves several organs.CD26 multifunctional molecule that has an extracellular domain with dipeptidyl peptidase IV activity digests crucial inflammatory molecules. CD26 plays important role in T-cell activation and enhances immune responses. This study was carried out to evaluate the level of gene expression SLE patients. Forty-six patients 44 healthy controls voluntarily participated this study. Based on index...
Radiotherapy is one of the most important methods for treatment breast cancer. There great interest in identifying factors that help to predict patient response radiotherapy. MicroRNAs (miRNAs) are a class small RNA molecules regulate gene expression at post-transcriptional level and play key role cellular responses ionising radiation. Several regulatory proteins participate tumour cell radiosensitivity there crosstalks between miRNAs these multiple levels. By analysing relationships...
Contrasting studies are reported on the induction of IL-10 and IFN-γ via chitin microparticles (CMPs) during immune stimulation. Our previous have shown marked protection among CMP treated Leishmania-infected mice regulated IL-10/IFN-γ response, at present study, once more, examined inconsistent responses regarding immunologic response CMPS. To verify whether CMPs could indeed up-regulate axis, isolated spleen cells from myelin oligodendrocyte glycoprotein (MOG) induced experimental...