The phytochemical investigation of Muehlenbeckia tamnifolia, collected in Loja-Ecuador, led to the isolation nine known compounds identified as: lupeol acetate (1); cis-p-coumaric acid (2); (3); β-sitosterol (4) trans-p-coumaric (5); linoleic (6) (+)-catechin (7); afzelin (8) and quercitrin (9). structures isolated were determined based on analysis NMR MS data, as well comparison with literature. hypoglycemic activity crude extracts was assessed by ability inhibit α-amylase α-glucosidase...

Objective: In this study, the chemical composition and biological activities of essential oils extracted from leaves fruits Zanthoxylum mantaro were analyzed. Methods: The obtained through hydrodistillation using a Clevenger-type apparatus. Chemical was determined by gas chromatography coupled with mass spectrometry (GC-MS) flame ionization detector (GC-FID). antimicrobial activity evaluated against four Gram-positive bacteria, three Gram-negative two fungi broth microdilution method....

Annona cherimola Mill. is a native species of Ecuador cultivated worldwide for the flavor and properties its fruit. In this study, hydrodistillation was used to isolate essential oil (EO) fresh leaves collected in Ecuadorian Sierra. The EO chemical composition determined using non-polar polar chromatographic column enantiomeric distribution with an enantioselective column. qualitative analysis carried out by gas chromatography coupled mass spectrometer quantitative equipped flame ionization...

Croton ferrugineus Kunth is an endemic species of Ecuador used in traditional medicine both for wound healing and as antiseptic. In this study, fresh leaves were collected subjected to hydrodistillation extraction the essential oil. The chemical composition oil was determined by gas chromatography equipped with a flame ionization detector coupled mass spectrometer using non-polar polar chromatographic column. antibacterial activity assayed against three Gram-positive bacteria, one...

A complete and comprehensive chemical biological study of Drimys granadensis, a native Ecuadorian aromatic plant, was conducted. By conventional steam distillation from dried leaves, yellowish, translucent essential oil (EO) with density 0.95 refractive index 1.5090 obtained. The EO analyzed by gas chromatography coupled to mass spectrometer (GC/MS) an FID detector (GC/FID), respectively. Enantiomeric distribution also carried out GC/MS using chiral selective column (diethyl...

The MeOH extract of Piper ecuadorense Sodiro, Piperaceae, was chosen for metabolite isolation and elucidation due to the strong antifungal activity exhibited, measured by means broth microdilution method. Two known flavonoids: pinostrobin (1) pinocembrin (2) were isolated from 4.16 g. dichloromethane column chromatography, using a gradient hexane/EtOAc. A total 20 mg 1 obtained fraction eluted with hexane-EtOAc 95:5 v/v, 100 2 85:15 v/v. MIC values 31.25 μg/mL Trichophyton mentagrophytes...

Scutellaria volubilis and Lepechinia paniculata belong to the Lamiaceae family of species. They are used widely in traditional medicine Ecuador. The physical properties chemical composition essential oils from aerial part its foliation – flowering stage phase have been studied after their hydrodistillation. components these were investigated by means gas chromatography/mass spectrometry (GC/MS) chromatography/flame ionization detection (GC/FID) techniques. Thirty-seven determined oil S....

In this research, the leaves of

The present study aimed to determine the chemical composition, enantiomeric distribution and biological profile of Hedyosmum strigosum essential oil (EO). antioxidant properties anticholinesterase effect were measured by spectroscopic methods antimicrobial potency assessed against 8 bacteria two fungi. H. is a native shrub, particularly found in Ecuador Colombia at 2000 3500 m a.s.l. Chemical composition was determined GC-MS GC-FID. A total 44 compounds detected, representing more than 92%...

Siparuna muricata is an aromatic native shrub or tree from Ecuador known as "limoncillo" "limón de la sierra" due to its citrus odor. In this study, the chemical composition and biological activity of essential oil leaves fruits species was determined. The isolated by subjected hydrodistillation. determined gas chromatography equipped with a flame ionization detector coupled mass spectrometry. enantiomeric distribution using enantioselective column. antimicrobial against three Gram-positive...

Hedyosmum purpurascens is an endemic species found in the Andes of Ecuador and it characterized by its pleasant smell. In this study, essential oil (EO) from H. was obtained hydro-distillation method with a Clevenger-type apparatus. The identification chemical composition carried out GC–MS GC–FID two capillary columns, DB-5ms HP-INNOWax. A total 90 compounds were identified, representing more than 98% composition. Germacrene-D, ϒ-terpinene, α-phellandrene, sabinene, O-cymene, 1,8-cineole...

The species Peperomia inaequalifolia, commonly known as congona, is a succulent herbaceous plant belonging to the Piperaceae family, which used for different purposes in traditional medicine. In this study, chemical composition, enantiomeric distribution, and biological activity of essential oil isolated from leaves was determined. Hydrodistillation isolate oil. Gas chromatography coupled mass spectrometry determine qualitative gas chromatograph equipped with flame ionization detector...

The essential oil of the species Clinopodium nubigenum (Kunth) Kuntze, Lamiaceae, was analyzed by GC-MS and GC-FID, taking into account more recent literature. Among seventy compounds identified, majority are oxygenated monoterpenoids. oil, tested for antimicrobial activity, resulted effective in vitro against Candida albicans. From aqueous MeOH extract aerial parts plant two nonvolatile compounds, named schizonepetoside A schizonepedoside C, have been isolated. They rare glycosyl...

The essential oil of aerial parts Baccharis latifolia (asteraceae) growing wild in Ecuador was obtained by hydrodistillation and analyzed gas chromatography/mass spectrometry (GC/MS) GC/flame ionization detector (GC/FID). Twenty-nine compounds, representing 90.91% the oil, were identified. major components limonene (33.72%), -phellandrene (10.32%), sabinene (10.28%), β-pinene (6.99%) α-pinene (5.44%). antifungal antibacterial activities determined broth microdilution method. from B....

Eduardo Valarezoa*, Jandry Rosalesa, Vladimir Morochoa, Luis Cartuchea, Diana Guayaa, Santiago Ojeda-Riascosa, Chabaco Armijosa & Silvia Gonzálezaa Departamento de Química, Universidad Técnica Particular Loja, Ecuador

The phytochemical investigation of both volatile and fixed metabolites Clinopodium taxifolium (Kunth) Govaerts (Lamiaceae) was performed for the first time. It allowed isolation characterization essential oil six known compounds: carvacrol (1), squalane (2), uvaol (3), erythrodiol (4), ursolic acid (5), salvigenin (6). Their structures were identified characterized by Nuclear Magnetic Resonance (NMR) Gas Chromatography coupled to Mass Spectroscopy (GC-MS), corroborated literature. leaves...

Due to the interesting potential of essential oils (EO) against cholinesterases and their close relation in Alzheimer's disease, EO Lepechinia betonicifolia (Lam) Epling (Lamiaceae), a native shrub from Ecuador, was assessed. Chemical profiling enantiomeric distribution were also recorded for first time.To analyse chemical profile including composition anticholinesterase effect exerted by L. betonicifolia.The fresh aerial parts obtained hydrodistillation Clevenger-type apparatus. Physical...

The species Croton elegans Kunth, belonging to the family Euphorbiaceae and known with common name "mosquera", is a native medicinal plant of Ecuador. Due its medical applications, we are interested in secondary metabolite composition. After extraction hexane preparation alkaloid extract, preparative chromatographic fractionation both normal direct phase was performed. 1H NMR, 13C HSQC HMBC experiments, together polarimetric measurements, were conducted order characterize purified compunds....

Our research focuses on exploring the chemical composition and some biological properties of essential oil derived from Syzygiella rubricaulis (Nees) Stephani, a bryophyte species. To conduct comprehensive analysis, we utilized DB5MS capillary column along with gas chromatography coupled to mass spectrometry (GC-MS) flame ionization (GC-FID). The qualitative quantitative examination revealed presence 50 compounds, hydrocarbon sesquiterpenes (48.35%) oxygenated (46.89%) being predominant...

The essential oil was obtained by steam distillation, using a Clevenger apparatus, from the pericarp of fruit

This article reports the chemical composition of essential oils obtained by hydrodistillation male and female H. scabrum fresh leaves. The oils, HSMO HSFO , respectively, were analyzed GC / MS ‐ FID . A total 93 components detected, accounting for 94.8% 95.3% respectively. prevalent constituents pinocarvone (13.1%), d ‐germacren‐4‐ol (12.6%), 1,8‐cineole (10.8%), α ‐pinene (6.4%), β (4.8%), whereas major (20.5%), linalool (16.5%), (15.0%), sabinene (6.3%). different enantiomeric distribution...

The phytochemical research on the species Siparuna echinata, collected in Province of Loja (Ecuador), led to isolation a rare sesquiterpenoid, called Sipaucin A. structure was confirmed by nuclear magnetic resonance (NMR) and mass spectrometry (MS). Furthermore, essential oil fruits obtained hydrodistillation analyzed gas chromatography, coupled (GC-MS) flame ionization detector (GC-FID). Twenty-seven compounds were identified polydimethylsiloxane column (DB-5ms) nineteen polyethylene glycol...

The number of colon cancer patients is increasing, and new alternatives for treatment are important. We focused on the sesquiterpene lactone onoseriolide from Hedyosmum racemosum, which widely used in traditional medicine. This compound was evaluated to determine its cytotoxic effect mechanism cell death that induced human line RKO. A dose-dependent decrease viability observed. p53 expression increased followed by an increase p21 expression, involved cycle arrest G2/M phase. Caspase-3...