An essential oil, distilled from the leaves of Andean species Gynoxys rugulosa Muschl., is described in present study for first time. The chemical composition was qualitatively and quantitatively determined by GC–MS GC–FID, respectively. On one hand, qualitative obtained comparing mass spectrum linear retention index each component with data literature. other quantitative calculating relative response factor constituent, according to its combustion enthalpy. Both analyses were carried out...

The present study is the first report on chemical and enantiomeric compositions of essential oils from Ecuadorian species Gynoxys hallii Hieron., calyculisolvens azuayensis Cuatrec. All volatile fractions presented a sesquiterpene-based profile, typical other this genus. Both qualitative (GC-MS) quantitative (GC-FID) analyses were carried out two stationary phases different polarity (non-polar polar). main constituents G. oil columns, respectively, α-pinene (33.6–31.5%), (E)-β-caryophyllene...

The essential oil (EO) obtained from the roots of Valeriana rigida Ruiz & Pav. (Caprifoliaceae), collected in moorland region Chimborazo Province, Ecuador, was analyzed for first time. chemical profile qualitatively and quantitatively using GC-MS GC-FID, respectively. With both detectors, two stationary phases different polarities were used. A total 56 compounds identified, most abundant components (>3% on at least one column) a mixture cyclosativene α-ylangene (4.5–4.4%), α-copaene...

The present study describes the chemical and enantiomeric composition of a new essential oil, distilled from dry leaves Gynoxys buxifolia (Kunth) Cass. analysis was conducted by GC-MS GC-FID, on two orthogonal capillary columns. A total 72 compounds were detected quantified with at least one column, corresponding to about 85% weight whole oil mass. Of components, 70 identified comparing respective linear retention indices mass spectra data literature, whereas main constituents preparative...

Abstract The essential oil obtained from the dry leaves of Gynoxys szyszylowiczii Hieron. was described in this study for first time. chemical analysis, conducted on two stationary phases different polarity, permitted to identify sixty-four compounds, that were quantified with at least one column. main components, a non-polar and polar phase respectively, germacrene D (21.6–19.2%), α-pinene (4.4–4.9%), n -tricosane (4.3% both columns), ( E )-β-caryophyllene (3.3–4.3%), 1-docosene (3.2–2.8%),...

A previously uninvestigated essential oil (EO) was distilled from Gynoxys miniphylla Cuatrec. (Asteraceae) and submitted to chemical enantioselective analyses. The qualitative quantitative analyses were conducted by GC-MS GC-FID, over two orthogonal columns (5%-phenyl-methylpolysiloxane polyethylene glycol stationary phases). Major constituents (≥2%) were, on both columns, respectively, as follows: α-phellandrene (16.1-17.2%), α-pinene (14.0-15.0%), germacrene D (13.3-14.8%), trans-myrtanol...

The fresh leaves of Gynoxys laurifolia (Kunth) Cass. (Asteraceae), collected in the province Loja (Ecuador), were submitted to steam distillation, producing an essential oil with a yield 0.02% by weight. This volatile fraction, described here for first time, was qualitative (GC-MS) and quantitative (GC-FID) chemical analyses, on two orthogonal columns (non-polar polar stationary phase). A total 90 components, corresponding 95.9-95.0% weight non-polar phase, respectively, detected quantified...

The present study belonged to an unfunded project, dealing on the systematic description of unprecedented essential oils (EOs), distilled from 12 species genus Gynoxys Cuatrec. In this very case, aim was first chemical and enantiomeric analyses two volatile fractions, obtained leaves cuicochensis sancti-antonii These EOs were analyzed by GC–MS (qualitatively) GC–FID (quantitatively), detecting 89 60 components G. sancti-antonii, respectively. Major for EO, a nonpolar polar stationary phase,...

The MeOH extract of Piper ecuadorense Sodiro, Piperaceae, was chosen for metabolite isolation and elucidation due to the strong antifungal activity exhibited, measured by means broth microdilution method. Two known flavonoids: pinostrobin (1) pinocembrin (2) were isolated from 4.16 g. dichloromethane column chromatography, using a gradient hexane/EtOAc. A total 20 mg 1 obtained fraction eluted with hexane-EtOAc 95:5 v/v, 100 2 85:15 v/v. MIC values 31.25 μg/mL Trichophyton mentagrophytes...

Scutellaria volubilis and Lepechinia paniculata belong to the Lamiaceae family of species. They are used widely in traditional medicine Ecuador. The physical properties chemical composition essential oils from aerial part its foliation – flowering stage phase have been studied after their hydrodistillation. components these were investigated by means gas chromatography/mass spectrometry (GC/MS) chromatography/flame ionization detection (GC/FID) techniques. Thirty-seven determined oil S....

Accumulating evidence supports the idea that secondary metabolites obtained from medicinal plants (phytometabolites) may be important contributors in development of new chemotherapeutic agents to reduce occurrence or recurrence cancer. Our study focused on Dehydroleucodine (DhL), a sesquiterpene found provinces Loja and Zamora-Chinchipe. In this study, we showed DhL displayed cytostatic cytotoxic activities human cerebral astrocytoma D384 cell line. With lactone isolated Gynoxys verrucosa...

The sesquiterpene lactones dehydroleucodine (1) and leucodine (2) were isolated from Gynoxys verrucosa, a species used in traditional medicine southern Ecuador. activity of these compounds was determined against eight acute myeloid leukemia (AML) cell lines compared with their normal peripheral blood mononuclear cells. Compound 1 showed cytotoxic the tested lines, LD50 values between 5.0 18.9 μM. 2 inactive all demonstrating that exocyclic methylene lactone ring is required for activity....

Blends of poly(lactic acid) (PLA) and poly(ε-caprolactone) (PCL), loaded with different amounts Amoxicillin antibiotic (AMOX) were electrospun to investigate their release properties obtain a controlled tuneable release. The processing parameters for electrospinning set up reliable membranes obtained. Morphology thermal behaviour found dependent on the component ratio as well incorporated drug amount. A very kinetics two pristine polymers, rapid PCL slow PLA, reflected in intermediate time....

Abstract The composition of the essential oils from leaves Lepechinia mutica , Satureja glabrata Minthostachys mollis and Myrcianthes rhopaloides four species used in traditional medicine Loja (Ecuador), was investigated by GC–FID GC–MS. Monoterpene hydrocarbons were main group constituents oil L. especially β ‐phellandrene (30%), whereas oxygenated monoterpenes predominated M. menthone (16%) geranial (34%), respectively, being major components. Although dominated S. (44%), constituent this...

The essential oil of the species Clinopodium nubigenum (Kunth) Kuntze, Lamiaceae, was analyzed by GC-MS and GC-FID, taking into account more recent literature. Among seventy compounds identified, majority are oxygenated monoterpenoids. oil, tested for antimicrobial activity, resulted effective in vitro against Candida albicans. From aqueous MeOH extract aerial parts plant two nonvolatile compounds, named schizonepetoside A schizonepedoside C, have been isolated. They rare glycosyl...

The essential oil of aerial parts Baccharis latifolia (asteraceae) growing wild in Ecuador was obtained by hydrodistillation and analyzed gas chromatography/mass spectrometry (GC/MS) GC/flame ionization detector (GC/FID). Twenty-nine compounds, representing 90.91% the oil, were identified. major components limonene (33.72%), -phellandrene (10.32%), sabinene (10.28%), β-pinene (6.99%) α-pinene (5.44%). antifungal antibacterial activities determined broth microdilution method. from B....

Amoxicillin (AMOX) was successfully encapsulated at different concentrations into poly(epsilon-caprolactone) (PCL) by the electrospinning technique, and mats of non-woven fibers were obtained characterized in terms morphology, vitro release antibacterial properties. The scanning electron microscopy evidenced nanofibrous structure pristine PCL, composed individual, uniform, randomly oriented fibres with an average diameter ranging around 0.8 micron. addition amoxicillin (3, 5 7 wt%) did not...

Gaiadandendron punctatum G.Don. (violeta de campo) is a plant used in traditional medicine by the Saraguro people, an ancient indigenous group that lives southern Ecuador. From samples collected region, six glycoside flavonoids, five with quercetin and one kaempferol as aglycon, were isolated characterized from hydroalcoholic extracts of leaves flowers. Rutin (2) was found flowers leaves, nicotiflorin (1) flowers, artabotryside A (3) three novel flavonoid glycosides isolated, elucidated, via...

ABSTRACTThe first chemical and enantioselective analyses of the essential oil from leaves Mauria heterophylla Kunth were carried out. The dry plant materialproduced an with a 0.09 ± 0.05% yield by weight. volatile fraction was submitted to GC-MS (qualitative) GC-FID (quantitative) analyses, on two different stationary phases. A total forty-four constituents detected quantified at least one column, corresponding about 85.5% whole mass. Limonene (15.2%), (E)-β-caryophyllene (11.1%),...

Abstract In the present study, essential oil from dry leaves of Steiractinia sodiroi (Hieron.) S.F. Blake is described for first time. The plant material, collected in Province Loja (Ecuador), was analytically steam-distilled a Marcusson-type apparatus, affording an with 0.2 ± 0.12% yield. volatile fraction submitted to GC–MS and GC–FID analyses, on two stationary phases different polarity. A total sixty-seven compounds, corresponding 95.6–91.2% by weight whole mass, columns respectively,...

Abstract The chemical composition of the essential oils from fresh leaves four species (Artemisia sodiroi, Siparuna eggersii, Tagetes filifolia and Clinopodium nubigenum), grown wild in southern Ecuador (province Loja), was examined through GC-MS analysis. In oil A. oxygenated monoterpenes were main group components, especially sabinyl acetate (65.8 %), while S. eggersii mainly composed by sesquiterpenes among which epicurzerenone (29.9 %) most representative. Conversely, aromatic...