Krishan K. Sharma

ORCID: 0000-0002-5621-1603
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About
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Research Areas
  • Pesticide Residue Analysis and Safety
  • Metal complexes synthesis and properties
  • Histone Deacetylase Inhibitors Research
  • Acute Myeloid Leukemia Research
  • Protein Degradation and Inhibitors
  • Magnetism in coordination complexes
  • Photochemistry and Electron Transfer Studies
  • Pesticide Exposure and Toxicity
  • Insect and Pesticide Research
  • Agricultural safety and regulations
  • Insect Resistance and Genetics
  • Organometallic Compounds Synthesis and Characterization
  • Analytical Methods in Pharmaceuticals
  • Analytical Chemistry and Chromatography
  • Lanthanide and Transition Metal Complexes
  • Advanced Chemical Physics Studies
  • Inorganic and Organometallic Chemistry
  • Chemical Reaction Mechanisms
  • Heat shock proteins research
  • Sensorless Control of Electric Motors
  • Sesquiterpenes and Asteraceae Studies
  • Vascular Malformations Diagnosis and Treatment
  • Plant Toxicity and Pharmacological Properties
  • Electric Motor Design and Analysis
  • Pediatric Urology and Nephrology Studies

Government Medical College, Amritsar
2024

Royal Perth Hospital
2024

Indian Agricultural Research Institute
2002-2023

Harvard University
2004-2023

Massachusetts General Hospital
2021-2023

Indian Council of Agricultural Research
2023

Singapore General Hospital
2021-2022

National Neuroscience Institute
2021-2022

All India Institute of Medical Sciences
2021-2022

Rabindranath Tagore Medical College
2021

Candida auris is a multidrug-resistant nosocomial fungal pathogen. While the marine environment was recently identified as natural niche for C. auris, environment(s) that might have contributed to development and spread of antifungal resistance in remains mystery. Because stored fruits are often treated with fungicides prevent postharvest spoilage, we hypothesized could serve possible selective force transmission reservoir antifungal-resistant isolates pathogenic yeasts, including auris. To...

10.1128/mbio.00518-22 article EN cc-by mBio 2022-03-31

Most patients with acute myelogenous leukemia (AML) relapse and die of their disease. Increasing evidence indicates that AML is driven by the inability to eradicate stem cells (LSC). Thus, it imperative identify novel therapies can ablate LSCs. Using an in silico gene expression-based screen for compounds evoking transcriptional effects similar previously described anti-LSC agent parthenolide, we identified AR-42 (OSU-HDAC42), a histone deacetylase inhibitor structurally phenylbutyrate, but...

10.1158/1535-7163.mct-13-0963 article EN Molecular Cancer Therapeutics 2014-06-17

Extraction and quantification of pesticide residue from the milk matrix at or below established maximum limit (MRL) is a challenging task for both analytical chemists regulatory institutions to take corrective actions human health safety. The main aim study develop simple rapid less expensive QuEChERS extraction cleanup method simultaneous analysis 41 multiclass in by gas chromatography-electron capture detector (GC-ECD), followed confirmation residues with chromatography-mass spectrometer...

10.1080/03601234.2019.1574169 article EN Journal of Environmental Science and Health Part B 2019-02-12

Cabbage, one of the most popular vegetables in world is infested by several insect-pests and diseases. Novaluron, a chitin synthesis inhibitor lambda-cyhalothrin, synthetic pyrethroid group insecticide are used to manage on cabbage. The dissipation kinetics risk assessment combination formulation (novaluron 9.45% + lambda-cyhalothrin 1.9%) with different modes action has not yet been investigated Multi–location supervised field trials were therefore, conducted agro-climatic regions India for...

10.1016/j.ecoenv.2020.111494 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2020-10-26

Background and Aims Plant-synthesized sesquiterpenes play a pivotal role in chemotactic interactions with insects. Biosynthesis of functionally diverse is dependent on the availability pool precursor farnesyldiphosphate (FDP). In Arabidopsis thaliana, FPS2, encoding cytosolic synthase, implicated synthesis FDP, but it not known whether enhanced levels FDP have commensurate effect sesquiterpene-mediated defence responses. This study examined transgenic arabidopsis plants generated to...

10.1093/aob/mcu250 article EN Annals of Botany 2014-12-20

The sesquiterpene lactones dehydroleucodine (1) and leucodine (2) were isolated from Gynoxys verrucosa, a species used in traditional medicine southern Ecuador. activity of these compounds was determined against eight acute myeloid leukemia (AML) cell lines compared with their normal peripheral blood mononuclear cells. Compound 1 showed cytotoxic the tested lines, LD50 values between 5.0 18.9 μM. 2 inactive all demonstrating that exocyclic methylene lactone ring is required for activity....

10.1021/acs.jnatprod.5b00383 article EN Journal of Natural Products 2016-04-08

To present the experience of pediatric percutaneous nephrolithotomy (PCNL) our center.This study was conducted from 1995 to 2015, on patients <15 years age having renal and upper ureteral stones who underwent PCNL. Stones were classified as per Guy's stone score (GSS). Standard bull's eye technique used for subcostal puncture. avoid supracostal puncture, puncture done in full inspiration or by oblique tract. If these maneuvers failed, then done. Tract dilated 24F.Six hundred sixty PCNLs...

10.1089/end.2015.0842 article EN Journal of Endourology 2016-12-14

Background Remote monitoring (RM) of cardiac implantable electronic devices has been shown to improve cardiovascular morbidity and mortality. To date, no studies have investigated disparities in use delivery RM. This study was performed investigate if racial socioeconomic are present device Methods Results a retrospective observational cohort at single tertiary care center the United States. Patients who received newly implanted or upgrade between January 2017 December 2020 were included....

10.1161/jaha.122.027500 article EN cc-by-nc-nd Journal of the American Heart Association 2023-01-23

Multi-location supervised field trials were conducted in India at four locations of the All Network Project (AINP) on Pesticide Residues to study persistence, dissipation and risk assessment flubendiamide deltamethrin cucumber (Cucumis sativus). resulting from three spray applications a combination formulation (flubendiamide 90% + 60%, 150 SC) recommended (22.5 15 g a.i./ha) double (45 30 dose analysed. On basis persistence studies, half- life (T1/2) varied 1.40 2.98 (recommended dose) 1.55...

10.1080/19440049.2017.1416678 article EN Food Additives & Contaminants Part A 2017-12-27

This paper presents a resonant type dual-band microstrip antenna with compact size. is realized by using an L-slot loaded ground. A dual band design presented for worldwide interoperability microwave access (WiMAX) and wireless local area network (WLAN) applications. The result shows that proposed achieves impedance bandwidth from 3.4 to 3.7 GHz 5.725 5.825 covering at 3.5 WiMAX 5.8 WLAN defected ground structure (DGS). provides good flexibility on selection of frequency operation modifying...

10.1109/ccaa.2015.7148595 article EN 2015-05-01

Both psychiatry as a specialty and mental illnesses carry lot of stigmatizing attitudes. Even medical professionals are not immune to prevailing stigma. Psychiatrists perceived have less scientific attitude, earn money, be respected, prestige.The present study was designed know the attitude students with different years exposure education, toward specialty.The conducted at JLN College, Ajmer. The participants were divided into two groups, undergraduate interns, respectively. It...

10.4103/ipj.ipj_82_17 article EN cc-by-nc-sa Industrial Psychiatry Journal 2018-01-01

Four new copper(<sc>ii</sc>)–polypyridyl complexes having tail groups with increasing aromaticity, hydrophobicity and planarity are synthesized. These found to be avid DNA binders show efficient nuclease activity under either chemical stimulus or UV-A light irradiation.

10.1039/c6nj00409a article EN New Journal of Chemistry 2016-01-01
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