- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Cholinesterase and Neurodegenerative Diseases
- Ethnobotanical and Medicinal Plants Studies
- Natural product bioactivities and synthesis
- Psidium guajava Extracts and Applications
- Medicinal Plants and Neuroprotection
- Chemical synthesis and alkaloids
- Traditional and Medicinal Uses of Annonaceae
- Piperaceae Chemical and Biological Studies
- Phytochemical Studies and Bioactivities
- Sesquiterpenes and Asteraceae Studies
- Allelopathy and phytotoxic interactions
- Phytochemistry and Bioactivity Studies
- Phytochemistry and Bioactive Compounds
- Seed and Plant Biochemistry
- Plant biochemistry and biosynthesis
- Phytochemicals and Antioxidant Activities
- Biochemical and biochemical processes
- Plant and soil sciences
- Insect Pest Control Strategies
- Phosphorus and nutrient management
- Natural Antidiabetic Agents Studies
- Botanical Research and Chemistry
- Layered Double Hydroxides Synthesis and Applications
Universidad Técnica Particular de Loja
2016-2025
Central University of Ecuador
2022
Universidad Nacional de Loja
2017
University of Pavia
2016
During the colonial period, indigenous saraguros maintained their traditions, knowledge, and practices to restore preserve health of members. Unfortunately, many medicinal resources have not been documented. In this study, we sought document traditional healers' (yachakkuna saraguros) knowledge about psychoactive plants used in mesas magical-religious rituals. The study was conducted under a technical scientific cooperation agreement between Universidad Técnica Particular de Loja (UTPL),...
The primary purposes of this work were to study the influence distillation temperature on yield turpentine essential oil hydrodistilled from Pinus roxburghii oleoresin and obtain products with powerful bioactivities by short path molecular oil. Our findings showed that hydrodistillation affected as well antioxidant antimicrobial properties oil: highest (20.27 %) obtained for distilled at 180 °C. was subsequently separated into fractions sub-fractions whose activity determined DPPH scavenging...
This paper reports the results of an ethnobotanical survey on use medicinal plants by community healers "Hampiyachakkuna" in San Lucas Parish, province Loja, Ecuador. A particular ethnic group, indigenous Saraguros, inhabits this region. study 183 plant species used 75 different curative therapies Saraguro healers.
Salvia pichinchensis Benth was collected in the South of Ecuador and essential oil (EO) distilled from aerial parts analyzed by GC-MS GC-FID.The physical properties, chemical composition, cholinesterase inhibitory activity were determined.Six major components, all sesquiterpenes, identified: cis-cadina-1(6),4-diene (17.11%) (1), γ-curcumene (13.75%) (2), (E)-caryophyllene (12.58%) (3), (E,E)-α-farnesene (10.00%) (4), α-gurjunene (9.46%) (5) allo-aromadendrene (6.96%) (6).The EO showed an...
Ecuador stands as a nation inheriting profound ancestral legacy in the utilization of medicinal plants, reflective rich biodiversity embraced by various ethnic groups. Despite this heritage, many these therapeutic resources remain insufficiently explored concerning their toxicity and potential pharmacological effects. This study focused on comprehensive evaluation cytotoxicity subcellular targets within extracts nine isolated metabolites from carefully selected plants. Assessing impact...
A study was undertaken with the aim of identifying a suitable plant for phytoremediation metal-polluted soil from an artisanal mining area in Ecuador. Three zones including natural zone (NZ), abandoned (AZ) and intensively mined (IZ) were selected. common native plants grown three identified collected, Miconia zamorensis, Axonopus compressus Erato polymnioides. The percentage arbuscular mycorrhizal colonization that benefits their own survival polluted analyzed root samples these candidate...
In southern Ecuador, horchata lojana is a popular aromatic and refreshing beverage that prepared from an aqueous infusion of different mixtures local medicinal plants. The drink considered traditional anti-inflammatory agent brain tonic; due these properties, it has been drunk since Colonial Times. Several pharmacological studies have evaluated the effects infusion. However, profile contribution volatile components to biological activity not investigated so far. For reasons, we determined...
Blends of poly(lactic acid) (PLA) and poly(ε-caprolactone) (PCL), loaded with different amounts Amoxicillin antibiotic (AMOX) were electrospun to investigate their release properties obtain a controlled tuneable release. The processing parameters for electrospinning set up reliable membranes obtained. Morphology thermal behaviour found dependent on the component ratio as well incorporated drug amount. A very kinetics two pristine polymers, rapid PCL slow PLA, reflected in intermediate time....
Lepechinia mutica (Benth.) Epling, Lamiaceae, and Vallea stipularis L.f., Elaeocarpaceae, are the object of present study. These plants endemic to Andean region have attracted our attention on basis interesting results obtained in a preliminary anticholinesterase screening. Actually, carnosol tiliroside, isolated from L. V. stipularis, respectively, shown promising selective inhibitory activity against butyrylcholinesterase. Specifically, anti-butyrylcholinesterase was 5.15 μM that...
Eduardo Valarezoa*, Jandry Rosalesa, Vladimir Morochoa, Luis Cartuchea, Diana Guayaa, Santiago Ojeda-Riascosa, Chabaco Armijosa & Silvia Gonzálezaa Departamento de Química, Universidad Técnica Particular Loja, Ecuador
This paper describes the chemical composition and enantiomer content of volatile oil hydrodistilled from Clinopodium brownei (Sw.) Kuntze, Lamiaceae. The plant was collected in South Ecuador. Thirty one components were identified by GC-MS, which accounted for 96.15% oil. major pulegone (48.44%), menthone (34.55%) β-acorenol (3.41%). Oxygenated monoterpenes (86.06%), followed oxygenated sesquiterpenes (5.36%) constituted most abundant fractions. enantiomeric compositions β-pinene, sabinene,...
The species Croton elegans Kunth, belonging to the family Euphorbiaceae and known with common name "mosquera", is a native medicinal plant of Ecuador. Due its medical applications, we are interested in secondary metabolite composition. After extraction hexane preparation alkaloid extract, preparative chromatographic fractionation both normal direct phase was performed. 1H NMR, 13C HSQC HMBC experiments, together polarimetric measurements, were conducted order characterize purified compunds....