Pierpaolo Medda

ORCID: 0000-0001-5163-3332
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About
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Research Areas
  • Electroconvulsive Therapy Studies
  • Bipolar Disorder and Treatment
  • Treatment of Major Depression
  • Attention Deficit Hyperactivity Disorder
  • Takotsubo Cardiomyopathy and Associated Phenomena
  • Electrolyte and hormonal disorders
  • Schizophrenia research and treatment
  • Coordination Chemistry and Organometallics
  • Autoimmune Neurological Disorders and Treatments
  • Obsessive-Compulsive Spectrum Disorders
  • Child and Adolescent Psychosocial and Emotional Development
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Functional Brain Connectivity Studies
  • Neural and Behavioral Psychology Studies
  • Memory and Neural Mechanisms
  • Dementia and Cognitive Impairment Research
  • Engineering Technology and Methodologies
  • Perfectionism, Procrastination, Anxiety Studies
  • Mental Health Research Topics
  • Adolescent and Pediatric Healthcare
  • Psychological and Temporal Perspectives Research
  • BIM and Construction Integration
  • Cancer Research and Treatment
  • Transcranial Magnetic Stimulation Studies
  • Aerosol Filtration and Electrostatic Precipitation

Azienda Ospedaliera Universitaria Pisana
2018-2025

University of Pisa
2014-2023

University of Cagliari
2014-2015

We evaluated the effectiveness of Electroconvulsive Therapy (ECT) in treatment Bipolar Disorder (BD) a large sample bipolar patients with drug resistant depression, mania, mixed state and catatonic features.522 consecutive DSM-IV-TR BD were prior to after ECT course. Responders nonresponders compared subsamples depressed patients. Descriptive analyses reported for mania features.Of original only 22 excluded occurrence side effects or consent withdrawal. After course, 344 (68.8%) considered...

10.2174/1570159x14666161017233642 article EN Current Neuropharmacology 2016-11-03

Objectives We describe the clinical characteristics and short‐term outcomes of a sample inpatients with bipolar disorder severe catatonic features resistant to pharmacological treatment. Methods The study involved 26 patients, trial benzodiazepines, then treated electroconvulsive therapy ( ECT ). All patients were evaluated prior one week following course using Bush–Francis Catatonia Rating Scale BFCRS ) Clinical Global Impression CGI Results In our sample, women over‐represented (n = 23,...

10.1111/bdi.12348 article EN Bipolar Disorders 2015-12-01

Objectives: The treatment of emotional dysregulation (ED) poses a major challenge for clinicians managing adult attention-deficit/hyperactivity disorder (ADHD). This naturalistic longitudinal study aimed to evaluate the effects combining mood stabilizers (MS) with standard pharmacotherapy in this population. Methods: Fifty-six patients ADHD, or without bipolar spectrum disorders, who were followed-up at least 4 months Pisa University Hospital included and grouped based on prescription ADHD...

10.3390/brainsci15020182 article EN cc-by Brain Sciences 2025-02-12

We compared the response with electroconvulsive therapy (ECT) of bipolar I patients resistant to pharmacological treatment, who presented depression or mixed state (MS).Ninety-six according Diagnostic and Statistical Manual Mental Disorders-Fourth Edition were included in study (46 major depressive episode 50 MS). Bilateral ECT was delivered using a brief pulse stimulator Mecta 5000Q (Mecta Corp, Lake Oswego, Ore) on twice-a-week schedule. The evaluated before (baseline) week after course...

10.1097/yct.0b013e3181b00f1e article EN Journal of Ect 2010-03-26

Article Abstract Objective: We prospectively evaluated the short-term outcome and predictors of response to electroconvulsive therapy (ECT) in a large sample patients with bipolar mixed state. Method: From January 2006 May 2011, we performed an analysis using data obtained from 197 203 consecutive state, according DSM-IV-TR diagnostic criteria, who were treated ECT at Department Psychiatry University Pisa. All prior after course Hamilton Depression Rating Scale-17 (HDRS-17), Young Mania...

10.4088/jcp.14m09181 article EN The Journal of Clinical Psychiatry 2015-04-14

Cerebral Small Vessel Disease (CSVD) is a chronic, progressive vascular disorder that confers increased vulnerability to psychiatric syndromes, including late-life mood disorders. In this study, we investigated the impact of CSVD on electroconvulsive therapy (ECT) outcomes in patients with late-onset bipolar (BD).

10.1002/gps.6098 article EN International Journal of Geriatric Psychiatry 2024-05-01

The aim of the present study was to evaluate long-term outcome in a sample patients with bipolar disorder severe depression or mixed-state resistant pharmacological treatment who have responded electroconvulsive therapy (ECT).The involved 36 major (5 I depression, and 14 II depression) mixed state (17 patients) treated bilateral ECT delivered using brief pulse stimulator Mecta 5000 Q on twice-a-week schedule. were evaluated before (baseline) 1 week after course (final score) Hamilton...

10.1097/yct.0b013e3182887b7a article EN Journal of Ect 2013-07-30

This study aimed to explore predictors of remission electroconvulsive therapy (ECT) in a sample depressive patients resistant pharmacological treatments.Two hundred eight patients, 31 whom had major disorder, 101 bipolar disorder II (BP II), and 76 I I), diagnosed according the Diagnostic Statistical Manual Mental Disorders, Fourth Edition criteria were treated with bilateral ECT on twice-a-week schedule. All included undergoing episode, excluding mixed manic episodes. Patients assessed...

10.1097/yct.0000000000000119 article EN Journal of Ect 2014-03-13

<b><i>Aims:</i></b> Alterations of plasma amyloid-β (Aβ) peptides have been related to a high risk for cognitive impairment and dementia. The present study aimed measure Aβ (Aβ40, Aβ42) the Aβ40/Aβ42 ratio in sample drug-resistant bipolar depressed patients, as well explore possible correlation between biological parameters clinical changes along an electroconvulsive therapy (ECT) course. <b><i>Methods:</i></b> Aβ40 Aβ42 were measured by means...

10.1159/000347082 article EN Neuropsychobiology 2013-01-01

AbstractObjectives The aim of this study was to identify clinical predictors treatment attrition, medication choice, improvement and response pharmacotherapy in adult attention-deficit/hyperactivity disorder (ADHD).Methods 150 ADHD patients were enrolled naturalistically followed-up for at least 4 months. Conners' Adult Rating Scales–Observer: Screening Version (CAARS-O:SV) used measure severity.Results 58 subjects (38.7%) lost follow-up, while 75 (50%) completed follow-up assessment, on...

10.1080/15622975.2023.2168750 article EN The World Journal of Biological Psychiatry 2023-01-13

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental condition that only rarely remits in adulthood. While several studies underlined differences between child and adult ADHD, the relationship clinical presentation early referral/treatment has been investigated. In our study, 100 adults with ADHD were recruited subdivided according to history of referral speciality care or treatment methylphenidate (MPH) during childhood/adolescence. The was associated disruptive behaviors...

10.3390/brainsci13091251 article EN cc-by Brain Sciences 2023-08-27

Neuropsychiatric symptoms (NPS) are common in the prodromal stage of dementia and can precede onset cognitive impairment. The presence NPS cognitively normal patients or with Mild Cognitive Impairment (MCI) is associated an increased risk progression along neurodegenerative process. need to identify, early stages disease, population at decline has led formulation concept Behavioral (MBI). This neurobehavioral syndrome characterized by late-onset sustained psychiatric symptoms, without...

10.1708/3142.31246 article EN PubMed 2019-04-16
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