A5066969274- Heart Rate Variability and Autonomic Control
- Tryptophan and brain disorders
- Cardiovascular and exercise physiology
- Non-Invasive Vital Sign Monitoring
- Stress Responses and Cortisol
- Dialysis and Renal Disease Management
- Attention Deficit Hyperactivity Disorder
- EEG and Brain-Computer Interfaces
- Neuroendocrine regulation and behavior
- Iron Metabolism and Disorders
- Infant Health and Development
- Psychosomatic Disorders and Their Treatments
- Health, psychology, and well-being
- Erythrocyte Function and Pathophysiology
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Bipolar Disorder and Treatment
- Bone health and osteoporosis research
- Trace Elements in Health
- Children's Physical and Motor Development
- HIV-related health complications and treatments
- Health Systems, Economic Evaluations, Quality of Life
- School Health and Nursing Education
- Child and Adolescent Psychosocial and Emotional Development
- Educational and Psychological Assessments
- Attachment and Relationship Dynamics
University of Pretoria
2013-2023
Onderstepoort Veterinary Academic Hospital
2012
Steve Biko Hospital
2002
University of the Witwatersrand
1979-1984
Chris Hani Baragwanath Hospital
1979-1982
<b><i>Background:</i></b> Despite strong reservations regarding the validity of a number heart rate variability (HRV) measures, these are still being used in recent studies. <b><i>Aims:</i></b> We aimed to compare reactivity ostensible sympathetic HRV markers (low and very low frequency [LF VLF]) that electrodermal activity (EDA), an exclusively marker, response cognitive orthostatic stress, investigate possibility LF as vagal-mediated marker...
Overweight and obesity in children adolescents are on the increase worldwide.Overweight risk for development of non-communicable diseases during childhood adolescence, predispose individual to overweight, obesity,ardiovascular disease, metabolic other disorders adulthood.In Africa number overweight or obese has doubled since 1990. In South Africa,overweight increase, but prevalencevaries with age, gender population group. These differences important when intervention programmes policies...
<i>Objective:</i> The aim of this study was to assess autonomic nervous system functioning in children with attention-deficit/hyperactivity disorder (ADHD) and examine the effects methylphenidate focussed attention. <i>Method:</i> Children ADHD (n = 19) were tested while they stimulant free during a period which on stimulants. On both occasions, at baseline Autonomic control subjects also activity determined by means heart rate variability (HRV) skin conductivity...
The effect of exercise interventions on autonomic nervous system (ANS) control the heart by rate variability (HRV) is often investigated in just one position. It was hypothesized that results exercise-induced changes ANS are dependent body position and it possible to distinguish between induced vagal sympathetic influence taking measurements different positions.One hundred eighty-three (male = 100, female 83) healthy volunteers, 18 22 years, participated a prospective twelve week medium high...
Previous studies of gastric secretory function and serum gastrin levels in patients with chronic renal failure (CRF) have yielded conflicting results. In a study 30 on regular hemodialysis, were higher than normal (p less 0.05), the response to pentagastrin was for group as whole. There were, however, 8 who hypochlorhydric (4 achlorhydric) 7 hyperchlorhydric. The hyposecretion older, predominantly male this associated highest well incidence gastrointestinal hemorrhage. Chronic gastritis is...
Background: Various disciplines use quantification of heart rate variability (HRV) as an indicator autonomic function without recognizing the importance using standardized methodologies. The aim this study was to assess influence tachogram length and period recording on HRV values. Methods: To test time, values calculated from 180, 300, 420, 600 seconds periods (supine standing) were compared. Also individual 3‐ minute (0–180 seconds, 180–360 360–540 seconds) 10‐minute tachograms Results: In...
Tryptophan is an essential amino acid for the synthesis of proteins and important metabolites such as serotonin, melatonin, tryptamine niacin. After protein synthesis, more than 90 % tryptophan catabolism occurs along kynurenine pathway. The inflammation-inducible enzyme indoleamine 2,3 dioxygenase (IDO) responsible first rate-limiting step in pathway, i.e., oxidation to kynurenine. Excessive IDO activity conditions HIV/AIDS may lead depletion accumulation downstream from Little known about...
The melatonin status of patients in end-stage chronic renal failure (CRF) was evaluated by the determination daytime plasma levels and investigation circadian rhythmicity secretion. A significant increase concentration found all CRF patient groups investigated, i.e. on conservative treatment (CT; n = 48), maintenance haemodialysis (HD; 39) peritoneal dialysis (PD; 32). Successful transplantation led to a marked reduction levels. rhythm secretion would appear be suppressed as nocturnal...
Forty-eight patients were subdivided according to C-reactive protein (CRP) levels, resulting in 19 with normal (2.8 ± 2.8 mg/L) and 29 elevated (82.2 76.2 CRP levels. The group had iron red blood cell (RBC) profiles characteristic of chronic immune stimulation (CIS), the group, true deficiency. Normal relationships between storage iron, bioavailable RBC indices absent group—implying role as major determinant profile be diminished during CIS. significant increases proinflammatory cytokines...
Cynicism, as a personality trait, has adverse effects on health. The question was asked whether cynical attitudes that develop due to work-related stress correlate with levels and it negative influence health.To investigate associations of the cynicism subscale scores Maslach Burnout Inventory-General Survey (MBI-GS) stress, anxiety, questionnaire-based physical health number physiological risk indicators.Cynicism, scores, well allostatic load, heart rate variability C-reactive protein, were...
Background: Uncertainty often exists about the comparability of results obtained by different health risk indicator systems.Objectives: To compare two systems, i.e, allostatic load and heart rate variability (HRV). Additionally, to investigate feasibility inclusion HRV indicators into assessments which are best introduce.Methods: Allostatic loads were calculated based on blood pressure, waist-to-hip ratio, BMI, cholesterol, HDL-C, LDL-C, CRP, albumin, glycosylated haemoglobin, glucose...
Indoor mould growth presents a potential health risk. The aim of this writing is to provide an overview on the pathophysiological aspects exposure dampness-associated indoor and mycotoxins. paper briefly deals with host's defence against invasion; mechanisms by which moulds can override mechanisms; adverse effects posed moulds, as well symptoms disorders associated including respiratory disorders, non-respiratory disorders. References recent in-depth reviews specific subject are provided....
The essential amino acid tryptophan cannot be synthesised in the body and must acquired through dietary intake. Oxidation of tryptophan, due to immune induction enzyme indoleamine 2,3-dioxygenase (IDO), is considered main cause depletion HIV infection AIDS. We examined plasma levels a low-income sub-Saharan HIV-infected population compared it that developed countries. Tryptophan were further context general nutritional inflammatory status.
Background: A general non-specific marker of disease activity that could alert the clinician and prompt further investigation would be value in patients with HIV/AIDS, especially resource limited environments.Objective: To investigate potential neopterin as biomarker advanced HIV/AIDS.Methods: Cross-sectional study 105 HIV positive (75 on highly active antiretroviral treatment (HAART). Neopterin was assessed by enzyme linked immune-absorbent assay cytokines flow cytometry.Results: levels...