A5089298785- Digital Holography and Microscopy
- Advanced X-ray Imaging Techniques
- Image Processing Techniques and Applications
- Cell Image Analysis Techniques
- Advanced Fluorescence Microscopy Techniques
- Optical measurement and interference techniques
- Random lasers and scattering media
- Modular Robots and Swarm Intelligence
- Microfluidic and Bio-sensing Technologies
- Optical Coherence Tomography Applications
- Breast Cancer Treatment Studies
- Nanofabrication and Lithography Techniques
- Micro and Nano Robotics
- Electrowetting and Microfluidic Technologies
- Optical Imaging and Spectroscopy Techniques
- Thermoregulation and physiological responses
- Biomedical and Engineering Education
- Near-Field Optical Microscopy
- Innovative Microfluidic and Catalytic Techniques Innovation
- Spectroscopy Techniques in Biomedical and Chemical Research
- Advanced Optical Imaging Technologies
- Virtual Reality Applications and Impacts
- Photoacoustic and Ultrasonic Imaging
- 3D Printing in Biomedical Research
- Advanced Electron Microscopy Techniques and Applications
Yonsei University
2009-2025
Seoul National University
2007-2025
University of California, San Francisco
2024
Macquarie University
2021-2024
Soongsil University
2024
Kyung Hee University
2014-2023
Viavi Solutions (United States)
2023
CHA University
2019-2022
CHA Bundang Medical Center
2019-2022
Kyung Hee University Hospital at Gangdong
2014-2020
We report a chip-scale lensless wide-field-of-view microscopy imaging technique, subpixel perspective sweeping microscopy, which can render images of growing or confluent cell cultures autonomously. demonstrate that this technology be used to build smart Petri dish platforms, termed ePetri, for culture experiments. This technique leverages the recent broad and cheap availability high performance image sensor chips provide low-cost automated solution. Unlike two major classes methods,...
We report on a compact, lensless and field-portable microscope using the camera module of smartphone ambient light for illumination.
We report the implementation of a fully on-chip, lensless, sub-pixel resolving optofluidic microscope (SROFM). The device utilizes microfluidic flow to deliver specimens directly across complementary metal oxide semiconductor (CMOS) sensor generate sequence low-resolution (LR) projection images, where resolution is limited by sensor's pixel size. This image then processed with super-resolution algorithm reconstruct single high (HR) image, features beyond Nyquist rate LR images are resolved....
Purpose: Bone is the most frequent site of metastasis among breast cancer patients.We investigated prognostic factors affecting survival following bone-only in patients.Materials and Methods: The medical records patients who were treated followed at Gangnam Severance Hospital retrospectively reviewed to identify with metastasis.Results: median time from diagnosis last follow-up or death was 55.2 [95% confidence interval (CI), 38.6-71.9]months.The Kaplan-Meier overall estimate 10 years for...
We propose a method for high-throughput generation of 3D microstructures using membrane-mounted microfluidic channel. Utilizing an optofluidic maskless lithography system, photopolymerized are fabricated in layer-by-layer fashion with the thickness each layer controlled by deformation membrane. The combination low numerical aperture optical systems photopolymerization and soft membrane height control allows large area projection high vertical resolution, overcoming trade-off between...
We developed Trap it!, a human-biology interaction (HBI) medium encompassing touchscreen interface, microscopy, and light projection. Users can interact with living cells by drawing on displaying the microscope view of cells. These drawings are projected onto microscopy field as patterns, prompting observable movement in phototactic responses. The system design enables stable robust HBI wide variety programmed activities (art, games, experiments). investigated its affordances an exhibit...
For centuries, observational microscopy has greatly facilitated biology education, but we still cannot easily and playfully interact with the microscopic world see. We therefore developed LudusScope, an accessible, interactive do-it-yourself smartphone platform that promotes exploratory stimulation observation of organisms, in a design combines educational modalities build, play, inquire. The LudusScope's touchscreen joystick allow selection phototactic microorganisms such as Euglena...
In recent years, breast implants have been frequently placed in the subcutaneous pocket, so-called prepectoral approach. We report our technique of implant-based reconstruction (IBR), as well its surgical and aesthetic outcomes, comparison with subpectoral IBR. also discuss relevant considerations pitfalls IBR suggest an algorithm for selection patients based on experiences.We performed 79 immediate reconstructions a implant acellular dermal matrix (ADM) sling, which 47 were IBRs 32 IBRs....
We propose a smartphone-mountable computational microscope that achieves wide-field and high-resolution imaging, based on the Fourier ptychographic (FP) microscopy technique. Our device uses smartphone's built-in camera for display screen programmable illumination, power of smartphone processors FP image reconstruction. With compact lightweight optics module custom-built application, we can transform regular into high-performance with space-bandwidth product exceeding benchtop microscopes....
We report tensorial tomographic Fourier ptychography (T2oFu), a nonscanning label-free microscopy method for simultaneous imaging of quantitative phase and anisotropic specimen information in 3D. Built upon ptychography, technique, T2oFu additionally highlights the vectorial nature light. The setup consists standard microscope equipped with an LED matrix, polarization generator, polarization-sensitive camera. Permittivity tensors samples are computationally recovered from polarized intensity...
Miniaturization of imaging systems can significantly benefit clinical diagnosis in challenging environments, where access to physicians and good equipment be limited. Sub-pixel resolving optofluidic microscope (SROFM) offers high-resolution the form an on-chip device, with combination microfluidics inexpensive CMOS image sensors. In this work, we report on implementation color SROFM prototypes a demonstrated optical resolution 0.66 µm at their highest acuity. We applied perform red blood...
Fourier ptychography (FP) is widely adopted for label-free, high-resolution quantitative phase imaging (QPI) of biological samples. However, its speed limited by the need multiple acquisitions. In this work, we propose a single-shot FP technique that uses linear polarizers to encode illumination wavevectors and polarization camera capture sets information simultaneously. A multiplexed algorithm, utilizing both bright-field dark-field information, reconstructs image from intensity image....
Objective: To examine the effects of a scapula-oriented exercise on upper limb dysfunction in breast cancer survivors. Study design: A prospective randomized, controlled pilot trial with historical control. Setting: Rehabilitation department at university hospital. Subjects: Thirty-two women were randomly assigned to group (n = 16) and general 16). An control 18) without was enrolled from Interventions: The exercises designed focusing scapulothoracic movement. performed body conditioning...
Self-imaging Petri dish platforms with microscopy resolution, which we term 'ePetri', can significantly streamline cell cultures and/or other longitudinal biological studies. In this paper, demonstrate high-resolution imaging and long-term culture of motile microorganisms in a specialized ePetri platform by taking advantage the inherent motion. By applying super-resolution algorithm to set low-resolution images as they move across sensing area complementary metal oxide semiconductor (CMOS)...
We present a lensless snapshot hyperspectral camera that is capable of imaging over broad spectrum using compact and low-cost hardware configuration. leverage the multiplexing capability camera, novel type computational device replaces lens with thin mask. Our utilizes linear variable filter phase mask to encode spectral information onto monochromatic image sensor, enabling recovery stacks from single measurement by utilizing encoded in different parts 2D point spread function. perform...
We demonstrate a compact portable imaging system for the detection of waterborne parasites in resource-limited settings. The previously demonstrated sub-pixel sweeping microscopy (SPSM) technique is lens-less scheme that can achieve high-resolution (<1 µm) bright-field over large field-of-view (5.7 mm×4.3 mm). A chip-scale microscope system, based on SPSM technique, be used automated and high-throughput protozoan parasite cysts effective diagnosis enteric infection. successfully imaged...
We present a hardware setup and set of executable commands for spatiotemporal programming interactive control swarm self-propelled microscopic agents (<italic>Euglena gracilis</italic>) inside microfluidic chip.
We investigate label-free measurement of molecular distribution by super-resolved Raman microscopy using surface plasmon (SP) localization. Localized SP was formed with plasmonic nanopost arrays (PNAs) for the in HeLa cells. Compared conventional on gold thin films, PNAs induce a localized near-field, which allows enhancement peak signal-to-noise ratio as much 4.5 dB shifts. Super-resolved distributions aromatic amino acids and lipids (C-C stretching C-H2 twist mode) targets cells were...