Chang‐Hun Lee

ORCID: 0000-0003-4330-7726
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About
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Research Areas
  • Orthopedic Surgery and Rehabilitation
  • Elbow and Forearm Trauma Treatment
  • Shoulder Injury and Treatment
  • Bone fractures and treatments
  • Sarcoma Diagnosis and Treatment
  • Peripheral Nerve Disorders
  • Tendon Structure and Treatment
  • Advanced Fluorescence Microscopy Techniques
  • Tracheal and airway disorders
  • Sports injuries and prevention
  • Nerve Injury and Rehabilitation
  • Salivary Gland Tumors Diagnosis and Treatment
  • Musculoskeletal synovial abnormalities and treatments
  • Railway Engineering and Dynamics
  • Oral and Maxillofacial Pathology
  • Mesenchymal stem cell research
  • Ecology and Conservation Studies
  • Anesthesia and Pain Management
  • Medical Imaging and Pathology Studies
  • Voice and Speech Disorders
  • Engineering Applied Research
  • Industrial Vision Systems and Defect Detection
  • Radiomics and Machine Learning in Medical Imaging
  • Semiconductor materials and devices
  • Osteoarthritis Treatment and Mechanisms

Hanyang University Seoul Hospital
2020-2025

Hanyang University
2012-2025

Daegu Gyeongbuk Institute of Science and Technology
2024

Pusan National University Hospital
2003-2024

Yonsei University
2019-2024

Chonbuk National University Hospital
2023-2024

Pusan National University
2007-2024

Anyang University
2020-2024

Pohang Accelerator Laboratory
2024

Pohang University of Science and Technology
2024

10.1142/9789814527859 article EN Gravitation and Cosmology 1999-02-01

Tooth infections or injuries involving dental pulp are treated routinely by root canal therapy. Endodontically teeth devitalized, susceptible to re-infections, fractures, and subsequent tooth loss. Here, we report regeneration of dental-pulp-like tissue cell homing without transplantation. Upon in vivo implantation endodontically real-size, native human mouse dorsum for the tested 3 weeks, delivery basic fibroblast growth factor and/or vascular endothelial (bFGF VEGF) yielded re-cellularized...

10.1089/ten.tea.2010.0181 article EN Tissue Engineering Part A 2010-05-20

We investigated the potential of a nanofiber-based poly(DL-lactide-co-glycolide) (PLGA) scaffold to be used for cartilage reconstruction. The mechanical properties nanofiber scaffold, degradation and cellular responses under stimulation were studied. Three different types (lactic acid/glycolic acid content ratio = 75 : 25, 50 50, or blend 25 50) tested. tensile modulus, ultimate stress corresponding strain scaffolds similar those skin slightly lower than human cartilage. This suggested that...

10.1163/156856206774879126 article EN Journal of Biomaterials Science Polymer Edition 2005-11-22

Gastric cancers have recently been classified into several types on the basis of molecular characterization, and new taxonomy has shown to clinical relevance. However, technology required for thorough classification is complicated expensive, currently preventing widespread use. We aimed reproduce results using only simple techniques, that is, immunohistochemical analysis in situ hybridization. a cohort 349 successive gastric adenocarcinomas 5 subtypes, protein or mRNA expression MLH1,...

10.1097/pas.0000000000000756 article EN The American Journal of Surgical Pathology 2016-11-05

We investigated the transport of neuronal mitochondria using superlocalized near-fields with plasmonic nanohole arrays (PNAs). Compared to traditional imaging techniques, PNAs create a massive array light beams and allow 3D mitochondrial dynamics be sampled extracted almost in real time. In this work, fluorescence excited by was captured an optical microscope dual objective lenses, which produced while minimizing scattering substrate. It found that move average velocity 0.33 ± 0.26 μm/s,...

10.1021/acsnano.8b08178 article EN ACS Nano 2019-02-25

Abstract This study aimed to evaluate the incidence rates of and risk factors for complex regional pain syndrome type 1 (CRPS-1) after surgery distal radius fractures (DRFs). Using data from January 2007 December 2014, we analysed Korean Health Insurance Review Assessment (HIRA) service. After extracting patients aged ≥18 years whose diagnostic operation codes DRFs were entered into HIRA database, CRPS-1. From 172,194 treated surgically. Within year postoperatively, 1,103 CRPS-1 cases...

10.1038/s41598-019-41152-x article EN cc-by Scientific Reports 2019-03-19

Little is known about whether clones of ectopic, non-muscle stem cells contribute to muscle regeneration. Stem/progenitor that are isolated for experimental research or therapeutics typically heterogeneous. Non-myogenic lineages in a heterogeneous population conceptually may compromise tissue repair. In this study, we discovered mononucleated human tooth pulp fused into multinucleated myotubes robustly expressed myosin heavy chain vitro with without co-culture mouse skeletal myoblasts (C2C12...

10.1371/journal.pone.0013547 article EN cc-by PLoS ONE 2010-10-20

The development of suitable synthetic scaffolds for use as human tendon grafts to repair ruptures remains a significant engineering challenge. Previous have demonstrated suboptimal tissue ingrowth and synovitis due wear particles from fiber-to-fiber abrasion. In this study, we present novel fiber-reinforced hydrogel (FRH) that mimics the hierarchical structure native graft material. Ultrahigh molecular weight polyethylene (UHMWPE) fibers were impregnated with either biosynthetic polyvinyl...

10.1021/acsbiomaterials.9b01716 article EN ACS Biomaterials Science & Engineering 2020-03-22

Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by ectopic bone formation. The anti-inflammatory function of dipeptidyl peptidase-4 (DPP4) inhibitor has been reported in metabolism, but its utility AS not previously investigated. We assessed DPP4 level serum, synovial fluid, and facet joint tissue patients. Additionally, we investigated the effect an experimental model using curdlan-injected SKG mice. Following curdlan injection, mice were orally administered...

10.1186/s13075-025-03474-2 article EN cc-by-nc-nd Arthritis Research & Therapy 2025-02-25

Few studies have reported the epidemiology of lateral epicondylitis (LE) and medial (ME) in nationwide databases. This study aimed to investigate LE ME South Korea. We analyzed data from database Korean Health Insurance Review Assessment Service 2013 2017. investigated incidence, prevalence, surgical trends patients with or ME. Between 2017, we identified 2813,431 836,610 ME, respectively. were more frequently diagnosed women than men. During period, mean annual age-adjusted incidence rates...

10.1097/md.0000000000041588 article EN cc-by-nc Medicine 2025-02-28

This study compares ultrasound and surgical findings of anatomical variations in de Quervain's disease. Seventy-four wrists from patients with unilateral disease were examined through ultrasonography surgery. Presence intracompartment septum, abductor pollicis longus (APL) slips, selective stenosis verified by both methods. Two orthopedic surgeons assessed for intra- interobserver reliability. Amongst 74 participants (43 women 31 men), 60.8% had a complete 31.1% an incomplete 8.1% no septum;...

10.4055/cios24127 article EN cc-by-nc Clinics in Orthopedic Surgery 2025-01-01

We investigate label-free measurement of molecular distribution by super-resolved Raman microscopy using surface plasmon (SP) localization. Localized SP was formed with plasmonic nanopost arrays (PNAs) for the in HeLa cells. Compared conventional on gold thin films, PNAs induce a localized near-field, which allows enhancement peak signal-to-noise ratio as much 4.5 dB shifts. Super-resolved distributions aromatic amino acids and lipids (C-C stretching C-H2 twist mode) targets cells were...

10.1021/acs.nanolett.0c04219 article EN Nano Letters 2020-11-13

To assess the incidence rate of carpal tunnel syndrome (CTS) in patients with rheumatoid arthritis (RA) and investigate correlations between CTS disease activity duration RA.This retrospective cohort study was conducted to 1070 RA who had visited our rheumatism center March 2001 May 2013, participated follow-up at least once over a 5-year period. We also investigated C-reactive protein (CRP) levels time occurrence identify RA, RA.The cumulative for 12 years 6.8% (12/176), 37 cases occurred...

10.1111/1756-185x.12445 article EN International Journal of Rheumatic Diseases 2014-09-08
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