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A5050904571
Research Areas
- Microstructure and Mechanical Properties of Steels
- Healthcare innovation and challenges
- Pregnancy and Medication Impact
- Health Services Management and Policy
- Pediatric Hepatobiliary Diseases and Treatments
- Elasticity and Material Modeling
- Drug Transport and Resistance Mechanisms
- Powder Metallurgy Techniques and Materials
University of Nottingham
2020
Background Intrahepatic cholestasis of pregnancy, characterised by maternal pruritus and raised serum bile acid concentrations, is associated with increased rates stillbirth, preterm birth neonatal unit admission. Ursodeoxycholic widely used as a treatment, but without an adequate evidence base. Objective We aimed to evaluate whether or not ursodeoxycholic reduces adverse perinatal outcomes in affected women. Design Multicentre, masked, randomised, placebo-controlled, two-arm, parallel-group...
10.3310/eme07090
article
EN
publisher-specific-oa
Efficacy and Mechanism Evaluation
2020-12-01
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