A5040675841- Microtubule and mitosis dynamics
- Ocular Oncology and Treatments
- Neuroblastoma Research and Treatments
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Cell Adhesion Molecules Research
- MicroRNA in disease regulation
- Retinal Development and Disorders
- Neuroendocrine Tumor Research Advances
- Lung Cancer Research Studies
University of Debrecen
2016-2020
Hematological and oncological disorders represent leading causes of childhood mortality. Neuropeptide somatostatin (SST) has been previously demonstrated in various pediatric tumors, but limited information exists on the expression characteristics SST receptors (SSTR) hematological children. We aimed to investigate mRNA for SSTR subtypes (SSTR-1–5) 15 hematological/oncological specimens by RT-PCR. The presence binding SSTRs were further studies ligand competition assay. Our results show that...
Uveal melanoma (UM) is the most common primary intraocular malignancy in adults, with an incidence of 4⁻5 cases per million. The prognosis UM very poor. In present study, our aim was to investigate expression mRNA and protein for somatostatin receptor types-1, -2, -3, -4, -5 (SSTR-1⁻5) human tissue samples OCM-1 OCM-3 cell lines by qRT-PCR, western blot ligand competition assay. SSTR-2 showed markedly higher tissues than SSTR-5. presence SSTRs demonstrated 70% specimens using assay both...