Introduction: Innovation of robotic surgery is still actively growing, and various novel systems are in the process development. The objective this study was to assess perioperative outcomes robot-assisted partial nephrectomy (RAPN) using hinotori surgical robot system, a recently developed platform, for patients with small renal tumors. Methods: This prospectively included total 30 consecutive who were found have tumors subsequently underwent RAPN between April November 2022. Major these...

The hinotori surgical robot system, a newly launched platform, has already been utilized in several urological robotic surgeries; however, limited information is available terms of its feasibility and safety each type surgery. objectives this study were to describe the perioperative outcomes first series six patients who underwent robot-assisted adrenalectomy (RAA) using hinotori, compare with similar set five undergoing RAA existing da Vinci.This included total 11 consecutive adrenal tumors...

This study was done to discover the underlying mechanism of inhibitory effect sericin against colon tumorigenesis. Mice were fed a diet with 30 g/kg for 115 d, and given weekly injection 1,2-dimethylhydrazine (10 mg/kg body weight) initial 10 wk. Dietary supplemental caused 62% reduction in incidence colonic adenoma (P<0.05), but did not affect adenocarcinoma. Sericin intake significantly reduced number adenomas. Consumption BrdU labeling index proliferating cells expression c-myc c-fos. The...

The aims of the present study were to describe perioperative findings first series patients undergoing robot-assisted radical nephrectomy (RARN) with a newly launched platform, hinotori surgical robot system, and compare similar set receiving RARN existing da Vinci.This included 34 patients, consisting 13 21 using Vinci robotic systems, respectively. As rule, was performed via an intraperitoneal approach employing 3 arms, irrespective systems.In group, median age, body mass index tumor...

Background/Aim: It is important to delay the emergence of castration-resistant phenotype improve prognosis in patients with metastatic castration-sensitive prostate cancer (mCSPC). The objective this study was investigate prognostic impact time castration resistance (TTCR) mCSPC patients. Patients and Methods: This included 437 consecutive whose primary androgen deprivation therapy judged have failed. Prognostic outcomes these were investigated by dividing them into following 4 groups 82,...

ABSTRACT Introduction Inferior vena cava (IVC) tumor thrombus occurs in 4%–10% of renal cell carcinoma (RCC) cases. Robotic‐assisted radical nephrectomy (RARN) with IVC thrombectomy offers a minimally invasive alternative to open surgery. Materials and Methods We retrospectively reviewed six cases RARN for RCC at two institutions between April 2022 August 2024. For left‐sided RCC, the left vein was transected using vascular stapler before thrombectomy, ensuring adequate access removal....

ABSTRACT Introduction Robot‐assisted radical cystectomy (RARC) is becoming the standard treatment for bladder cancer patients. While this surgery using da Vinci has been widely reported, report describes initial experience of RARC with intracorporeal neobladder hinotori surgical robot system. Case Presentation The patient was a 73‐year‐old man muscle‐invasive who underwent neoadjuvant chemotherapy followed by hinotori. Surgery successfully performed total operative time 430 min, robotic...

Background: The hinotori surgical robot system is a promising robotic platform that has been recently introduced into routine clinical practice. aim of this study was to report our initial experience robot-assisted radical nephroureterectomy (RANU) using hinotori. Methods: This included total eight patients with upper urinary tract tumor (UUTT) who underwent RANU via the transperitoneal approach. In series, nephrectomy initially performed at kidney direction stage followed by distal...

The objective of this study was to compare the prognostic outcomes between metastatic castration-sensitive prostate cancer (mCSPC) patients receiving conventional androgen deprivation therapy (ADT) and those ADT plus a novel androgen-receptor signaling inhibitor (ARSI) in routine clinical practice Japan.

Although a number of studies have been carried out to examine the biological effects radiation and ultraviolet (UV), little is known concerning visible light. In present study, exposure B16 melanoma cells blue light (wavelength 470 nm, irradiance 5.7 mW / cm(2)) from light-emitting diode (LED) inhibited cell growth in proportion period exposure, with no increase observed dead cells. The colonies that formed after for 20 min was only slightly less than non-exposed controls, but colony size as...

Recently we reported that the supplementation of vitamin B6 to low diet caused suppression in colon tumorigenesis and cell proliferation azoxymethane-treated mice a dose-dependent manner among 1, 7, 14 mg pyridoxine HCl/kg (J. Nutr. 131: 2204-2207, 2001). To examine mechanism anticolon tumor effect B6, male ICR were fed containing 14, 35 for 22 wk simultaneously given weekly injection azoxymethane an initial 10 wk. The (1 HCl/kg) suppressed levels colonic 8-hydroxyguanosine 4-hydroxynonenal...

This review describes effects of miso with reference to prevention radiation injury, cancer and hypertension a twin focus on epidemiological experimental evidence. Miso longer fermentation time increased crypt survival against injury in mice. When evaluating different types provided by areas Japan, fermented for period the number surviving crypts, 180 days was most significant. Dietary administration 180-day inhibits development azoxymethane (AOM)-induced aberrant foci (ACF) rat colon...

Abstract BACKGROUND AND HYPOTHESIS Soybean isoflavones have been shown to reduce the risk of cerebral infarction in humans according epidemiological studies. However, whether intake miso can incidence stroke animal models remains unknown. In this study, we investigated effects soybean paste (miso) an model stroke. METHODS Stroke-prone spontaneously hypertensive rats (SHRSP) were fed a diet (normal 90%, 10%; final NaCl content 2.8%), high salt and 2.5%; or low diet; 0.3%). RESULTS...

The objective of this study was to evaluate the initial learning curve for robot-assisted partial nephrectomy (RAPN) using da Vinci Xi Surgical System (Intuitive Surgical, Sunnyvale, California).This included 65 consecutive patients with small renal tumors who had undergone RAPN at our institution. A single trained surgeon extensive experience in radical prostatectomy, but not laparoscopic nephrectomy, performed all Xi. analyzed by examining perioperative outcomes among five groups each...

Background/Aim: The therapeutic impact of combination treatment with an immune checkpoint inhibitor (ICI) and chemotherapeutic agent on patients urothelial cancer (UC) remains controversial. Therefore, the present study investigated differences in effects therapy cisplatin plus anti-mouse programmed death (PD)-1 antibody according to dose using mouse bladder tumor model MBT2. Materials Methods: two different doses and/or PD-1 growth after subcutaneous injection MBT2 cells were compared....