A5100733183- Sleep and related disorders
- Sleep and Wakefulness Research
- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Circadian rhythm and melatonin
- Sleep and Work-Related Fatigue
- Functional Brain Connectivity Studies
- Heart Rate Variability and Autonomic Control
- EEG and Brain-Computer Interfaces
- Suicide and Self-Harm Studies
- Non-Invasive Vital Sign Monitoring
- Mental Health Research Topics
- Restless Legs Syndrome Research
- Psychosocial Factors Impacting Youth
- Dementia and Cognitive Impairment Research
- Schizophrenia research and treatment
- Posttraumatic Stress Disorder Research
- Child and Adolescent Psychosocial and Emotional Development
- Youth Substance Use and School Attendance
- Migration, Health and Trauma
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Parkinson's Disease Mechanisms and Treatments
- Neural dynamics and brain function
- Mental Health Treatment and Access
- Bipolar Disorder and Treatment
Seoul National University Hospital
2015-2024
Seoul National University
2015-2024
Korea University
2024
Samsung Medical Center
2017-2024
Sungkyunkwan University
2017-2024
New Generation University College
2016-2023
GTx (United States)
2020-2022
Kangwon National University
2022
In-Q-Tel
2020
University of Ulsan
2018
To investigate the association between behaviorally induced insufficient sleep and suicidality among adolescents.A population-based, cross-sectional survey.General community.A sample of 8,530 students (grades 7-11) was recruited in Republic Korea. The participants were 8,010 who completed all questionnaires.N/A.The survey included Beck Scale for Suicidal Ideation (SSI), Depression Inventory (BDI), a modified Epworth Sleepiness (ESS), questionnaires about (weekday/weekend schedule/duration,...
Objective The Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's disease (KBASE) aimed to recruit 650 individuals, aged from 20 90 years, search new biomarkers (AD) investigate how multi-faceted lifetime experiences bodily changes contribute brain or pathologies related AD process. Methods All participants received comprehensive clinical neuropsychological evaluations, multi-modal imaging, including magnetic resonance angiography, [11C]Pittsburgh compound...
Background:The objective of this article is to assess the mental health issues mild condition coronavirus disease 2019 (COVID-19) patients admitted a community treatment center (CTC) in Korea.Methods: A total 107 CTC were included as study population, and their problems including depression (patient questionnaire-9), anxiety (generalized disorder scale-7), post-traumatic stress (PTSD) (PTSD checklist-5) somatic symptoms (by patient questionnaire-15) evaluated every week during stay.The...
Manual scoring of sleep stages from polysomnography (PSG) records is essential to understand the quality and architecture. Since PSG requires specialized personnel, a lab environment, uncomfortable sensors, non-contact staging methods based on machine learning techniques have been investigated over past years. In this study, we propose an attention-based bidirectional long short-term memory (Attention Bi-LSTM) model for automatic stage using impulse-radio ultra-wideband (IR-UWB) radar which...
Abstract BACKGROUND. Papillary thyroid cancers often occur as multiple foci. Multifocal have been considered to a poor prognosis because they are thought be the consequence of intrathyroidal spread papillary cancer. However, authors' knowledge there has little investigation into whether multifocal carcinomas arise from single carcinoma or independent primary tumors. To answer this question, BRAF V600E mutational status individual tumor foci was examined. This approach justified in Korean...
To investigate the relationship between insufficient sleep and poor attention in Korean adolescents, adjusting for potential confounding factors of depressed mood habitual snoring.School-based cross-sectional study.Eight high schools 3 cities Republic Korea.A sample 2638 urban school students (42.2% male 57.8% female; mean [SD] age, 17.3 [0.6] years [age range, 14-19 years]) completed questionnaires computerized tasks during term.Weekend catch-up sleep.Self-reported schedules habits,...
We established and tested an unconstrained sleep apnea monitoring method using a polyvinylidene (PVDF) film-based sensor for continuous accurate of apneic events occurred during sleep. Twenty-six patients six normal subjects participated in this study. Subjects' respiratory signals were measured the PVDF-based polysomnography. The PVDF comprised 4 × 1 array, thin silicon pad was placed over to prevent damage. Total thickness merged system approximately 1.1 mm which enough subject from being...
The present study investigated academic performance among adolescents with behaviorally induced insufficient sleep syndrome (BISS) and attempted to identify independent predictors of BISS-related factors.A total 51 students BISS 50 without were recruited from high schools in South Korea based on self-reported weekday durations, weekend oversleep, the Epworth Sleepiness Scale (ESS). Participants reported their form class quartile ranking. Korean version Composite (KtCS) for...
Objective: Nocturnal pulse oximetry has been proposed as a simpler alternative to polysomnography in diagnosing sleep apnea. However, existing techniques are limited terms of inability provide time information on apnea occurrence. This study aimed propose new strategy for near real-time automatic detection apneic events and reliable estimation apnea-hypopnea index using nocturnal oximetry. Methods: Among 230 polysomnographic recordings with values ranging from 0 86.5 events/h, 138 (60%) the...
Objective Previous studies have indicated that suicide rates significant seasonal variations. There is discordance between temperature and solar radiation due to the monsoon season in South Korea. We investigated seasonality of assessed its association with climate variables Method Suicide were obtained from National Statistical Office Korea, climatic data Korea Meteorological Administration for period 1992–2010. conducted analyses using a generalized additive model ( GAM ). First, we...
To examine the resting-state functional connectivity (FC) between subcortical regions in relation to whole-brain activity patients with psychophysiological insomnia (PI) and changes following cognitive-behavioral therapy for (CBTi).The FC seed (caudate, putamen, pallidum, amygdala, thalamus, hippocampus) voxels were compared PI group (n = 13, mean age: 51.0 ± 10.2 years) good sleepers (GS, n 18, 42.7 12.3 years). Also, group, was before after 5 weeks of CBTi.Compared GS exhibited stronger...
The use of telemedicine with a mobile application (MA) and wearable device (WD) for the management sleep disorders has recently received considerable attention. We designed an MA synchronizable WD insomnia treatment. Our pilot study determined efficacy simplified group cognitive behavioral therapy (CBT-I) delivered using our assessed participant adherence to satisfaction device.The CBT-I (CBT-I-MA) was by comparing variables (sleep efficiency [SE], Insomnia Severity Index [ISI], Pittsburgh...
The aim of this study is to determine whether GlcN could recover the endoplasmic reticulum (ER) stress-induced dysfunction Na(+) /glucose cotransporter (SGLT) in renal proximal tubule cells (PTCs) under hypoxia. With rabbit model, ischemia induced tubulointerstitial abnormalities and decreased SGLTs expression tubular brush-border, which were recovered by GlcN. Thus, protective mechanism against was being examined using PTCs. Hypoxia level protein O-GlcNAc transferase (OGT) while increased...
Circadian typology and sleep quality may be essential factors associated with the promotion of resilience. However, previous studies investigating association between circadian resilience did not analyze effects on Thus, present study evaluated in Korean college students after controlling for quality. Additionally, this investigated several sleep-related variables, including duration, social jetlag sunlight exposure during daytime, to examine modifiable behavioral features morningness also...
The most widely used methods for predicting obstructive sleep apnea are based on clinical or anatomico-functional features. To improve exactitude in screening, this study aimed to devise a new predictor of apnea-hypopnea index. We hypothesized that less irregular respiration cycles would be observed the patients with more severe during sleep-onset period. From each 156 and 70 single-lead electrocardiograms collected from internal polysomnographic database Physionet Apnea-ECG database,...
We investigated the prevalence of insomnia and its clinical characteristics in North Korean refugees.North refugees living South Korea (48 males, 129 females; mean age 38.22±12.24 years) Koreans (112 203 39.48±10.32 completed following questionnaires: Self-reported Questionnaire on Insomnia, Center for Epidemiological Studies-Depression Scale (CES-D), Trauma Exposure Check List Refugees, Impact Event Scale-Revised (IES-R).North had more often than did (38.42% vs. 8.89%). Depression combined...
This study was performed to investigate the associations of life event stress with impulsivity, anxiety, and depressed mood as a function presence sleep disturbance.In total, 214 participants (age 38.96±10.53 years; 111 females) completed self-report questionnaires, including Life Experience Survey (LES), Pittsburgh Sleep Quality Index (PSQI), Barratt's Impulsivity Scale (BIS), Beck Anxiety Inventory (BAI), Depression (BDI). The disturbance defined PSQI score >5.In 127 presented 39.33±10.92...