Objective Dickkopf-1 (DKK-1), a major regulator of the Wnt pathway, plays an important role in cardiovascular disease. However, no study has evaluated association DKK-1 and acute coronary syndrome (ACS). We investigated this whether Global Registry Acute Coronary Events (GRACE) hospital-discharge risk score predicting adverse cardiac events (MACE) can be improved by adding value. Methods enrolled 291 patients (46 with ST-segment elevation myocardial infarction [STEMI] 245 non-ST elevated ACS...

This study aimed to describe the sleep quantity, quality, and daily rest periods (DRPs) of Japanese permanent daytime workers.Information about usual DRP, quality (Japanese version Pittsburgh Sleep Quality Index: PSQI-J) 3,867 workers in Japan was gathered through an Internet-based survey. information analyzed divided into following eight DRP groups: <10, 10, 11, 12, 13, 14, 15, ≥16 h.The durations for h groups were found be 5.3, 5.9, 6.1, 6.3, 6.5, 6.7, 6.9 h, respectively. The trend...

BackgroundHigh levels of control over working time and low variability in hours have been associated with improved health-related outcomes. The potential mechanisms for this association remain unclear.

The purpose of the present study was to compare physiological responses different types mental stress encountered in workplace. Circulatory and central nervous system were examined 8 healthy males by exposing them 20-min white noise (80 dB(A)) computer-based arithmetic tasks as models vascular cardiac stress, respectively. results indicated that both stresses increased blood pressure showed a cumulative effect exposure period extended. Heart rate prefrontal oxygenated hemoglobin levels...

Abstract One hundred and fifty GCN5-like acetyltransferases with amino acid-binding (ACT)-GCN5-related N-acetyltransferase (GNAT) domain organization have been identified in actinobacteria. The ACT is fused to the GNAT domain, conferring acid-induced allosteric regulation these protein (Pat) (amino acid sensing acetyltransferase, (AAPatA)). Members of AAPatA family share similar secondary structure are divided into two groups based on ligands domain: asparagine (Asn)-activated PatA cysteine...

Positive emotion is considered as an important factor related to health-relevant biological processes, including cardiovascular responses. To explore the possibility of using positive a tool manage response white-collar workers, we examined influence on inducement before mental work. Seventeen healthy males participated and performed 10-min, PC-based Stroop color word task their Before task, 60 pleasant pictures chosen from International Affective Picture System were presented in random...

Abstract Objectives The incidence of occupational low back pain (LBP) is high among caregivers. use care equipment and training about methods could prevent LBP However, in facilities Japan, these measures are not adequately employed. Moreover, the have faced issues regarding poor staffing recent years. present study investigated relationship between safety health activities (OSHAs) for preventing caregivers aimed to validate priority approaches OSHA. Methods This cross-sectional was...

The purpose of this study was to clarify the causes low back pain among workers in care facilities for elderly after introduction welfare equipment.We conducted anonymous questionnaire surveys administrators and eight facilities. questionnaires were designed investigate status both facility. In reference facility, comprised items investigating basic information, occupational safety, health activities. For workers, addition activities, also resident transfer bathing methods, pain,...

This study aimed to examine hemodynamic responses and the necessity of breaks under long working hours. Thirty-eight healthy males conducted PC-based work from 9:10 22:00. Nine 10-minute short two (a 1-hour break a 50-minute break) were provided, measured regularly during this period. The results showed that systolic blood pressure increased hours cardiovascular burden Cardiac decreased, but vascular continually periods without breaks. breaks, however, benefitted workers by preventing...

This observational study aimed to determine how 1-year changes in work time control (WTC) have an impact upon objectively measured fatigue and sleep among employees.Thirty-nine employees were divided into two groups according whether or not their WTC increased from baseline 1 year later. Psychomotor vigilance task (PVT) wrist actigraphy used measure sleep, respectively. Self-reported outcomes also measured.The group showed gradual improvements PVT performance quality over the course of...

Summary The daily rest period (DRP) is the inter‐work interval and can include a sleep opportunity, leisure time, other non‐work time. A longer DRP may allow workers to increase time in bed (TIB) adjust timing, that reduce problems such as short duration, debt, social jetlag, poor quality. present study examined longitudinal association between these among Japanese daytime workers. DRP, TIB on workdays, quality (Pittsburgh Sleep Quality Index [PSQI]), debt jetlag were measured November 2016...

Interest of human adaptability to city life is one the most principal topics physiological anthropology. Especially, cultural adaptation and flowing stresses by itself important viewpoint in recent modern life. In this paper, authors reviewed keywords anthropology, especially with focus on techno-adaptability, presented our experimental trials study polymorphism cardio-vascular reactivity mental stresses. We scoped psychological means tasks as an model techno-stress. Techno-stress was...

Many care workers at elderly facilities in Japan suffer occupational low back pain (LBP) despite the utilization of welfare equipment.When introducing equipment such as hoists and sliding boards, education on appropriate methods using is usually conducted, but effect diminishes with time.This intervention study aimed to examine re-education prevention workers' LBP an facility.At facility, 49 were enrolled ergonomic program for 1.5 yr order improve equipment.At non-intervention 33 not...

The objectives of this study were to evaluate the antimicrobial efficacy cinnamon essential oil (CEO) and rosemary (REO) against 4 food-related microorganisms. chemical components CEO REO also analyzed by GC/MS. major active constituents cinnamaldehyde (80.010%) 2-methoxycinnamaldehyde (10.550%), 1,8-Cineole (51.783%) α-Pinene (13.508%).The results indicated that both them display strong inhibition strains. combination showed additive all tested Thus, our demonstrated can be considered...

Objectives The present study examined hemodynamic responses of normotensive and untreated hypertensive participants under simulated long working hours (LWH) – 13 in an experimental laboratory study. Methods Thirty-five men participated this Twenty-two these were categorized into the group (systolic blood pressure (SBP) ≤140 mmHg diastolic (DBP) ≤90 mmHg); one participant was excluded due to missing data, leaving twenty-one with a mean age 49.2 years. Another thirteen high (SBP=140–160 or...

While a number of work-related events have been proposed as risk factors for depression, majority studies focused only on few in single study. Therefore, we conducted web-based longitudinal study to comprehensively investigate the impact various depressive symptoms. Ten thousand Japanese workers representing working population were recruited online and questioned their experiences 36 past year. Their symptoms also assessed based Center Epidemiologic Studies Depression Scale. Two years later,...

In Japan, the practice of no-lift policy, which states that care recipients should be lifted with equipment rather than by human power, has been increasing since around 2014. The purpose this study was to examine whether severe low back pain (LBP) risk factors in caregivers changed between 2014 and 2018. A questionnaire survey targeting administrators working facilities for elderly conducted total 612 2,712 responded questionnaires 2014, 504 3,478 completed percentage who experienced LBP did...

Palliative care involves providing comprehensive physical, psychological, and social to improve clinical symptoms quality of life, as well ensure patients' dignity at the end life. Nurses are important members hospice teams, undergraduate nursing students providers future. The ability provide will, thus, directly affect service quality. To understand relationship between competence death-coping abilities a theoretical basis for promoting development education students. A convenience sample...

This paper proposes an obstacle avoidance scheme of a novel mobile robot system for automatic search books in libraries based on the radio frequency identification (RFID). Nowadays, most utilize barcode technique, since it is low cost. However, our experiments show that using RFID adequately can save more labor and improve library management efficiency, has many advantages, i.e., large information storage long distance, etc., whose application great development potential. Based advantages...