A5009840963- Sepsis Diagnosis and Treatment
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiac Arrest and Resuscitation
- Trauma and Emergency Care Studies
- Cardiac electrophysiology and arrhythmias
- Vehicle Routing Optimization Methods
- Ion channel regulation and function
- Traumatic Brain Injury and Neurovascular Disturbances
- Facility Location and Emergency Management
- Hemodynamic Monitoring and Therapy
- COVID-19 Clinical Research Studies
- Respiratory Support and Mechanisms
- Venous Thromboembolism Diagnosis and Management
- Multiferroics and related materials
- Nosocomial Infections in ICU
- Cardiac Ischemia and Reperfusion
- Intensive Care Unit Cognitive Disorders
- Long-Term Effects of COVID-19
- Blood Coagulation and Thrombosis Mechanisms
- Mechanical Circulatory Support Devices
- Numerical methods in engineering
- Politics and Society in Latin America
- Avian ecology and behavior
- Composite Material Mechanics
- Neuroscience and Neural Engineering
Hokkaido University
2015-2025
Hokkaido University Hospital
2012-2024
The University of Tokyo
2012-2024
GTx (United States)
2024
Tokyo Metropolitan Geriatric Hospital
2023
Kumamoto University
2023
Juntendo University
2016-2023
Kyushu University
2023
Saga University
2023
Osaka University of Pharmaceutical Sciences
2023
Neutrophil elastase plays an important role in the development of acute respiratory distress syndrome (ARDS) and disseminated intravascular coagulation (DIC) sepsis. Sivelestat is a selective neutrophil inhibitor. It possible that sivelestat improves outcome septic patients associated with ARDS DIC. A retrospective data analysis DIC was conducted to investigate effects sivelestat. Observational period 5 days after admission intensive care unit (ICU). The study included 167 Control group 133...
Japanese Association for Acute Medicine (JAAM) disseminated intravascular coagulation (DIC) criteria were launched nearly 20 years ago. Following the revised conceptual definition of sepsis and subsequent omission systemic inflammatory response syndrome (SIRS) score from latest diagnostic criteria, we omitted SIRS proposed a modified version JAAM DIC JAAM-2 criteria.
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are characterized by a disruption of the endothelium alveolar epithelial barriers involving increased microvascular permeability, thus resulting in set protein-rich pulmonary edema. Angiogenic factors their receptors, including vascular endothelial growth factor (VEGF)/VEGF-receptor (VEGFR) angiopoietin (Ang)/Tie2 signaling pathways, play pivotal roles both angiogenesis permeability. The aim study was to assess...
There have been inconsistent reports regarding the effect of antithrombin on sepsis; furthermore, there are limited how dosage affects therapeutic efficacy. Thus, we aimed to perform a systematic review and meta-analysis use for sepsis meta-regression analysis dosage.
Background: The criteria for diagnosing sepsis-induced coagulopathy (SIC) may overlap with those of Japanese Association Acute Medicine (JAAM) disseminated intravascular coagulation (DIC). We aimed to determine if the diagnostic SIC JAAM DIC diagnosis International Society on Thrombosis and Haemostasis (ISTH) whether patients have same prognosis when diagnosed using these criteria. Methods: This multicenter retrospective study included sepsis ISTH days 1 4. established was reference standard...
There is evidence to demonstrate that the coagulopathy which occurs in patients with traumatic brain injury coincides disseminated intravascular coagulation (DIC). We hypothesized DIC increased fibrinolysis during early stage of isolated (iTBI) affects outcome and hypoperfusion contributes hyperfibrinolysis DIC.This retrospective study included 92 iTBI who were divided into non-DIC groups according Japanese Association Acute Medicine scoring system. The subdivided those without...
We hypothesized that activated protein C does not increase in disseminated intravascular coagulation (DIC) after trauma and the same is true for acute coagulopathy of trauma-shock (ACOTS). Activated levels were prospectively measured 57 patients: 30 with DIC 27 without DIC. Normal to more decreased observed patients than controls non-DIC patients. The ACOTS similar those In conclusion, either or early phase trauma.