A5013235288- Bone health and treatments
- Bone health and osteoporosis research
- Bone and Joint Diseases
- Parathyroid Disorders and Treatments
- Hip and Femur Fractures
- Rheumatoid Arthritis Research and Therapies
- Bone Metabolism and Diseases
- Hip disorders and treatments
- Systemic Lupus Erythematosus Research
- Spinal Cord Injury Research
- Vitamin D Research Studies
- Bone Tumor Diagnosis and Treatments
- Cerebral Palsy and Movement Disorders
- Spinal Fractures and Fixation Techniques
- Orthopedic Infections and Treatments
- Connective tissue disorders research
- Bone fractures and treatments
- Dermatological and Skeletal Disorders
- Liver Disease Diagnosis and Treatment
- Liver Diseases and Immunity
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Heterotopic Ossification and Related Conditions
- Body Contouring and Surgery
- Otitis Media and Relapsing Polychondritis
- Inflammatory Myopathies and Dermatomyositis
Hospital Universitari Germans Trias i Pujol
2017-2024
Universitat Autònoma de Barcelona
2023-2024
Center for Rheumatology
2017-2018
Universitat de Barcelona
2010-2017
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2013-2017
University of Wisconsin–Madison
2017
Hospital Clínic de Barcelona
2010-2016
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2013-2016
Vall d'Hebron Hospital Universitari
1993
Bone strength is determined not only by bone quantity [bone mineral density (BMD)] but also quality, including matrix composition, collagen fiber arrangement, microarchitecture, geometry, mineralization, and turnover, among others. These aspects influence elasticity, the load-bearing repair capacity of bone, microcrack propagation are thus key to fractures their avoidance. In chronic kidney disease (CKD)-associated osteoporosis, factors traditionally associated with a lower mass (advanced...
Osteoporosis resulting in bone fractures is a complication patients with primary biliary cirrhosis (PBC). Once-weekly alendronate improves mass and well tolerated these patients, but there concern because of poor compliance. Therefore, the efficacy, adherence, safety monthly ibandronate (150 mg) weekly (70 were compared randomized, 2-year study 42 postmenopausal women PBC osteoporosis. Bone mineral density (BMD) lumbar spine proximal femur (by DXA), liver function, markers measured at entry...
Objective: To analyse the incidence and factors related to development clinical evolution of fractures in patients with traumatic spinal cord injury. Design: A retrospective 10-year follow-up study. Setting: Neurorehabilitation centre. Subjects: Sixty-three (50M/13F) a mean age 36 ± 20 years recent injury attended over one-year period (January December 2000). Main measures: Medical reports were reviewed, evaluating risk for osteoporosis, fracture during 10 following injury, severity (ASIA...
Abstract Spinal cord injury (SCI) has been associated with a marked increase in bone loss and remodeling, especially short-term after injury. The absence of mechanical load, mediated by osteocyte mechanosensory function, seems to be causative factor related this condition. However, the pathogenesis clinical management process remain unclear. Therefore, aim study was analyze effect recent SCI on Wnt pathway antagonists, sclerostin Dickkopf (Dkk-1), their relationship turnover mineral density...
ABSTRACT Sclerostin is involved in the regulation of osteoblastogenesis and little known about its role development bone disease primary biliary cirrhosis (PBC), characterized by low formation. Therefore, we have assessed circulating levels liver expression sclerostin this cholestatic disease. Serum were measured 79 women with PBC (mean age 60.6 ± 1.2 years) 80 control women. Lumbar femoral mineral density (BMD), as well parameters metabolism remodeling, measured. Moreover, gene (SOST) was...
Fracture risk assessment in patients with chronic kidney disease (CKD) has been included the CKD-MBD ("Chronic Kidney Disease-Mineral and Bone Disorders") complex international national nephrology guidelines, suggesting for first time of bone mineral density (BMD) if results can influence therapeutic decision-making. However, there is very little information on actual clinical practice this population. The main objective ERCOS (ERC-Osteoporosis) study to describe profile CKD G3-5D...
Hereditary multiple exostosis (HME) or diaphysial aclasis is an autosomal dominant condition characterized by exostoses which appear in different parts of the skeleton (Solomon, 1963). Lesions occur infants and children usually cease to enlarge at puberty. Complications are uncommon, haemothorax has occasionally been described (Balatskii et al, 1973; Proper 1980; Tejeira 1989). We report a patient presenting with spontaneous as complication costal exostoses. A 19-year-old boy known have was...