A5044222104- Nanoparticles: synthesis and applications
- Nanoparticle-Based Drug Delivery
- Wound Healing and Treatments
- Skin Protection and Aging
- Epilepsy research and treatment
- Advancements in Transdermal Drug Delivery
- Pharmacological Effects and Toxicity Studies
- HIV/AIDS drug development and treatment
- Pharmacological Effects of Natural Compounds
- Medicinal Plants and Neuroprotection
- Colorectal Cancer Treatments and Studies
- Advanced Nanomaterials in Catalysis
- Bioactive Compounds and Antitumor Agents
- Photodynamic Therapy Research Studies
- melanin and skin pigmentation
- Oral Health Pathology and Treatment
- Iron oxide chemistry and applications
- Graphene and Nanomaterials Applications
- Copper-based nanomaterials and applications
- Advanced Drug Delivery Systems
- Antimicrobial agents and applications
- Free Radicals and Antioxidants
- Phytochemistry and Bioactivity Studies
- Silk-based biomaterials and applications
- Cancer therapeutics and mechanisms
Sohag University
2020-2024
Al-Ayen University
2024
Thi Qar University
2024
Skin is the largest mechanical barrier against invading pathogens. Following skin injury, healing process immediately starts to regenerate damaged tissues and avoid complications that usually include colonization by pathogenic bacteria, leading fever sepsis, which further impairs complicates process. So, there an urgent need develop a novel pharmaceutical material promotes of infected wounds. The present work aimed prepare evaluate efficacy azithromycin-loaded zinc oxide nanoparticles...
Infected wounds pose a significant challenge in healthcare, requiring innovative therapeutic strategies. Therefore, there is critical need for pharmaceutical materials to improve wound healing and combat bacterial growth. This study examined the efficacy of azithromycin-loaded silver nanoparticles (AZM-AgNPs) treating infected wounds. AgNPs synthesized using green method with Quinoa seed extract were loaded AZM. Characterization techniques, including X-ray Powder Diffraction (XRD), scanning...
Colorectal cancer (CRC) is the third highest major cause of morbidity and mortality worldwide. Hence, many strategies approaches have been widely developed for treatment. This work prepared evaluated antitumor activity 5-Fluorouracil (5-Fu) loaded chromium nanoparticles (5-FuCrNPs). The green biosynthesis approach using Harpullia (H) pendula aqueous extract was used CrNPs preparation, which further with 5-Fu. NPs were characterized morphology scanning transmission electron microscopes (SEM...
A new Schiff base (H2L) generated from sulfamethazine (SMT), as well its novel micro- and nanocomplexes with Ni(II) Cd(II) metal ions, have been synthesized. The proposed structures of all isolated solid compounds were identified physicochemical, spectral, thermal techniques. Molar conductance studies confirmed that the complexes are not electrolytic. molecular geometry located at central ion was found to be square planar for NiL2 tetrahedral CdL2 complexes. kinetic parameters obtained using...
The present paper evaluates the photocatalytic degradation (PCD) performance of biofabricated hematite nanoparticles (α-HNPs) for approach Cefotaxime (Cfm). optimum pH solution to achieve best PCD was found be 10.5. kinetics study Cfm via α-HNPs has been investigated and reaction fellow pseudo-first-order at R
The delivery of drugs via fast dissolving films is an effective alternative for with low bioavailability when administered by other routes. This the case domperidone (DMP) anti-emetic drug water solubility and vulnerable to extensive first-pass effect. To overcome these limitations, in this work, we designed produced muco-adhesive buccal using varying amount polyvinylpyrrolidone (PVP K-90) solvent casting method. Films loaded more than 10% were not homogenous opaque as indicated white...
Vicia faba seeds are a rich source of polyphenolic, and flavonoid compounds that have high antioxidant activity. The aqueous extract V. has been used for the biosynthesis nanocomposite (NC) consisting three different types nanoparticles deposited onto each other as [email protected]2[email protected]. Physicochemical, optical, electrical, morphological properties as-biofabricated protected] NC were characterized using analytical techniques X-ray diffraction (XRD), Fourier-transform infrared...
A novel derivative of ciprofloxacin (Cpx) was synthesized and characterized using various analytical techniques, including FT-IR spectroscopy, UV-Vis TEM SEM analysis, 1H NMR, 13C HPLC analysis. The newly prepared Cpx (Cpx-Drv) exhibited significantly enhanced antibacterial properties compared to itself. In particular, Cpx-Drv demonstrated a 51% increase in activity against S. aureus 30% improvement B. subtilis. It displayed potent inhibitory effects on topoisomerases II (DNA gyrase...
High mortality and morbidity rates are related to hepatocellular carcinoma (HCC), which is the most prevalent type of liver cancer. A new vision for cancer treatment cell targeting has emerged with application nanotechnology, reduces systemic toxicity adverse effects chemotherapy medications while increasing their effectiveness. It was goal proposed work create investigate an anticancer C@Fe@Cu nanocomposite (NC) loaded Doxorubicin (DOX) HCC. Scanning transmission electron microscopes (SEM...
Photodynamic therapy (PDT) can be defined as the administration of a nontoxic drug or dye known Photosensitizer (PS) either systemically, locally, topically to patient bearing lesion. Methylene blue considered photosensitizer for photodynamic therapy. Current topical and oral therapies acne vulgaris have limited efficacy, especially in moderate severe cases, In view this, aim our study was use methylene form niosomal hydrogel treatment acne. To reach this objective we studied following...
Wound healing is a significant healthcare problem that decreases the patient’s quality of life. Hence, several agents and approaches have been widely used to help accelerate wound healing. The challenge search for topical delivery system could supply long-acting effects, accurate doses, rapid activity. Topical forms simvastatin (SMV) are beneficial in care. This study aimed develop novel chitosan-based platform SMV with folic acid (FA) Moreover, synergistic effect combinations was determined...
Simvastatin (SMV) is a well-known antihyperlipidemic drug that has demonstrated wound healing effects. However, its clinical application hindered by poor solubility. Therefore, the objective of this study was to enhance solubility simvastatin utilizing various concentrations solvents and co-solvents for formulation in selected topical dosage forms. Mixed-solvent systems, namely Buffer-methanol, Buffer-ethanol, Buffer-dmso, were employed. Additionally, impact different polymer concentrations,...
Background and Aim:Common wart is considered one of the common diseases that are caused by human papillomavirus; despite high tendency for spontaneous recovery, it needs treatment.Topical application keratolytic agent on virus-infected cells standards in treatment, potassium hydroxide [KOH] a strong, less irritating agent, painful, can be safely used all age groups.This study aimed to evaluate topical 10% KOH treatment warts as regards safety efficacy. Patients methods:This open therapeutic...