A5014073865- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Phytochemicals and Antioxidant Activities
- Nanoparticles: synthesis and applications
- Nanoparticle-Based Drug Delivery
- Graphene and Nanomaterials Applications
- Natural Antidiabetic Agents Studies
- Natural product bioactivities and synthesis
- Drug-Induced Hepatotoxicity and Protection
- Advanced Drug Delivery Systems
- Synthesis and biological activity
- Computational Drug Discovery Methods
- Laser-Ablation Synthesis of Nanoparticles
- Alzheimer's disease research and treatments
- RNA Interference and Gene Delivery
- Phytochemistry and Bioactivity Studies
- Ethnobotanical and Medicinal Plants Studies
- Phytochemistry and biological activities of Ficus species
- Parkinson's Disease Mechanisms and Treatments
- Curcumin's Biomedical Applications
- Advancements in Transdermal Drug Delivery
- Advanced Nanomaterials in Catalysis
- Drug Solubulity and Delivery Systems
- Wound Healing and Treatments
- Moringa oleifera research and applications
Qassim University
2019-2025
Al-Azhar University
2014-2024
Al-Azhar University
2022-2024
Zagazig University
2024
American Pharmacists Association
2019
Medicina
2019
Al al-Bayt University
2016
Saarland University
2011-2013
Okayama University
1999
Abstract Zinc oxide-silver (ZnO–Ag), and zinc oxide-gold (ZnO–Au) nano-composites were prepared through wet chemical process laced into single-walled carbon nanotubes (SWCNTs) to yield ZnO–Ag-SWCNTs, ZnO–Au-SWCNTs hybrids. These nano-composite-laced SWCNTs hybrids characterized using Raman spectroscopic, X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission (TEM) analyses. The evaluated for their effects on phagocytic cells bactericidal activity against the gram-negative...
The purpose of this study was to evaluate the potential a newly modified cyclodextrin derivative, water-soluble β-cyclodextrin–epichlorohydrin (β-CD), as an effective drug carrier enhance poor solubility and bioavailability galangin (GAL), poorly model drug. In regard, inclusion complexes GAL/β-CDP were prepared. UV-VIS spectrophotometry, Fourier-transform infrared spectroscopy (FTIR), X-ray crystallography (XRD), zeta analysis, particle size field emission scanning electron microscopy...
Abstract Solid lipid nanoparticles (SLNs), the spheroidal-shaped, colloids state lipophilic-natured, innovative nanoscale particulate materials, are being concurrently prepared by quality-by-design approach for cellular and sub-cellular delivery of drugs other payloads with facilitated physicochemical characteristics targeted delivery. The drugs, pharmaceuticals biopharmaceutical genes to diseased body organs, tissues, mass have been developed as promising nanocarriers different...
Silver nanoparticles (AgNPs) have demonstrated numerous physicochemical, biological, and functional properties suitable for biomedical applications, including antibacterial drug carrier properties. In the present study, antibiotic, ciprofloxacin (CIP), was loaded onto AgNPs, which were synthesized via chemical reduction method, thereby enhancing CIP's activity against Gram-negative (Acinetobacter baumannii Serratia marcescens) Gram-positive (Staphylococcus aureus) bacterial strains....
Aims: To evaluate the anti breast-cancer activity, biocompatibility and toxicity of poly(d,l)-lactic-co-glycolic acid (PLGA)-encapsulated quercetin nanoparticles (Q-PLGA-NPs). Materials & methods: Quercetin was nano-encapsulated by an emulsion-diffusion process, were fully characterized through Fourier transform infrared spectroscopy, x-ray diffractions, FESEM zeta-sizer analysis. Activity against CAL51 MCF7 cell lines assessed DNA fragmentation assays, fluorescence microscopy,...
Nanoparticle development demonstrates use in various physicochemical, biological, and functional properties for biomedical applications, including anti-cancer applications. In the current study, a cancer therapeutic conjugate was produced consisting of tamoxifen (TAM) resveratrol (RES) by layer-by-layer (LbL) nanoparticles based on lipid-based drug delivery systems liquid crystalline (LCNPs) coated with multiple layers positively charged chitosan negatively hyaluronic acid evaluation...
Zygophyllum coccineum, an edible halophytic plant, is part of the traditional medicine chest in Mediterranean region for symptomatic relief diabetes, hypertension, wound healing, burns, infections, and rheumatoid arthritis pain. The current study aimed to characterize Z. coccineum phytoconstituents, evaluations anti-microbial-biofilm, anti-cancers bioactivities plant’s mother liquor, i.e., aqueous-ethanolic extract, its subsequent fractions. silico receptors interaction feasibility major...
Artemisia judaica (ArJ) is a Mediterranean aromatic plant used traditionally to treat gastrointestinal ailments, skin diseases, atherosclerosis, and as an immuno-stimulant. This study describes ArJ essential oil constituents investigates their wound healing activity. The in vitro antioxidant antibiofilm activities of were investigated. vivo pro/anti-inflammatory oxidative/antioxidant markers compared with standard silver sulfadiazine (SS) second-degree burn experimental rat model. gas...
Abstract There is a need to formulate oral cetuximab (CTX) for targeting colorectal cancer, which reported express somatostatin receptors (SSTRs). Therefore, coating CTX with analogue such as octreotide (OCT) beneficial. Alginate was used coat facilitate delivery the gastrointestinal tract (GIT). This study aimed deliver conjugated OCT in form of microparticles GIT-targeted SSTR therapy. Both and were using solvent evaporation method CTX-OCT then loaded onto Ca-alginate-beads (CTX-OCT-Alg),...
Streptomyces smyrnaeus UKAQ_23, isolated from the mangrove-sediment, collected Jubail,Saudi Arabia, exhibited substantial antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA), including non-MRSA Gram-positive test bacteria. The novel isolate, under laboratory-scale conditions, produced highest yield (561.3 ± 0.3 mg/kg fermented agar) of compounds in modified ISP-4 agar at pH 6.5, temperature 35 °C, inoculum 5% v/w, 1.5% w/v, and an incubation period 7 days. two...
Six flavonoids present in Pulicaria jaubertii, i.e., 7,3'-di-O-methyltaxifolin (1), 3'-O-methyltaxifolin (2), 7-O-methyltaxifolin (3), taxifolin (4), 3-O-methylquercetin (5), and quercetin (6), were tested for their anticancer activities. The methylated flavonoids, compounds 1-3 5, evaluated activities comparison to the non-methylated parent (4) (6). structures of known reconfirmed by spectral analyses using 1H 13C NMR data comparisons HRMS spectrometry. activity these was colon cancer,...