A5085958101- Venous Thromboembolism Diagnosis and Management
- Nutrition and Health in Aging
- Atrial Fibrillation Management and Outcomes
- Sepsis Diagnosis and Treatment
- Liver Disease Diagnosis and Treatment
- Frailty in Older Adults
- Acute Ischemic Stroke Management
- Tracheal and airway disorders
- Cancer Mechanisms and Therapy
- Gastrointestinal Tumor Research and Treatment
- Genetic factors in colorectal cancer
- Sleep and related disorders
- Health Systems, Economic Evaluations, Quality of Life
- Inflammatory Biomarkers in Disease Prognosis
- Cancer Risks and Factors
- Adolescent Sexual and Reproductive Health
- Obesity, Physical Activity, Diet
- Genetic Associations and Epidemiology
- Sex work and related issues
- Obstructive Sleep Apnea Research
- HIV/AIDS Research and Interventions
- Circular RNAs in diseases
- Colorectal Cancer Treatments and Studies
- Cleft Lip and Palate Research
- Colorectal Cancer Screening and Detection
China Medical University
2020-2025
Lishui Central Hospital
2024
Wenzhou Medical University
2024
First Affiliated Hospital of Xi'an Jiaotong University
2023
First Hospital of Jilin University
2023
Jilin University
2023
Xi'an Jiaotong University
2023
ABSTRACT Previous research indicates an association between sleep traits and venous thromboembolism (VTE) risk, though causal relationships remain uncertain. This study evaluated combined independent associations VTE risk using UK Biobank data explored the through two‐sample Mendelian randomization (MR) analyses. Hazard ratios (HRs) 95% confidence intervals (95% CIs) for healthy score, as well individual (including duration, insomnia, daytime sleepiness, snoring, chronotype), were calculated...
Radiotherapy is the standard adjuvant treatment for esophageal squamous cell carcinoma (ESCC), yet radioresistance remains a major obstacle leading to failure and unfavorable prognosis. Previous reports have demonstrated involvement of astrocyte elevated gene-1 (AEG-1) in tumorigenesis progression multiple malignancies. Nevertheless, precise role AEG-1 ESCC elusive. Here, we unveiled strong correlation between aberrant gene overexpression malignant as well adverse prognosis patients....
Abstract Unsafe sex has become a public safety problem that endangers society, and research on deaths disability-adjusted life years (DALYs) related to unsafe is valuable for global policy-making. We aimed estimate the DALYs attributable by country, gender, age group, sociodemographic status from 1990 2019. extracted data disease burden Global Disease Burden 2019 (GBD 2019) database sex, including deaths, age-standardized rates (ASRs). Comparative analyses were performed about responding...
Concurrent chemoradiotherapy is the preferred treatment for stage IVB cervical cancer; however, some patients experience a poor prognosis. The prognostic significance of body composition indicators, including visceral obesity, has been extensively investigated in with cancer. This study aimed to assess impact specifically pretreatment fat content, on survival outcomes We retrospectively analyzed clinical information from diagnosed cancer between 2010 and 2018. measured obesity...
Abstract Background Frailty, defined as a phenotype of decreased physiological reserves and diminished ability to respond stressors, has been linked the development chronic diseases. Epidemiological evidence connecting frailty non‐alcoholic fatty liver disease (NAFLD) cirrhosis risks remain sparse. We aimed assess longitudinal associations with severe NAFLD in middle‐aged older adults further explore modification role genetic risk on these associations. Methods This study included total 398...
Childhood obstructive sleep apnea hypopnea syndrome (OSAHS) is a common clinical disease that can cause serious complications if not treated in time. Adenoidectomy with or without tonsillectomy the most important first line surgical treatment of children. The aim this study was to compare differences between these two procedures for adenoidectomy terms operation time, intraoperative blood loss, proportion patients experiencing postoperative delayed hemorrhage, and incidence adverse events.
Background: Accelerated biological ageing has been linked to the development of chronic diseases. However, evidence associations between accelerated and risks non-alcoholic fatty liver disease (NAFLD) cirrhosis are still lacking. We aimed assess acceleration (BAA), genetic susceptibility, NAFLD cirrhosis, as well BAA with life expectancy in individuals different NAFLD/cirrhosis conditions.Methods: A total 277,057 participants free from UK Biobank were included this cohort study. Biological...
Interventional therapy, currently, has become a major method for the clinical treatment of liver cancer patients. However, interventional therapy can also lead to various toxic side effects, and combined with impact disease itself, patients often experience more severe emotional distress. Improving individuals' levels psychological distress tolerance may reduce sensitivity negative life events experiences. At this stage, there is no relevant literature reporting on after therapy. This study...
Colon cancer is a malignant tumor with high malignancy and low survival rate whose heterogeneity limits systemic immunotherapy. Transforming growth factor-β (TGF-β) signaling pathway-related genes are associated multiple tumors, but their role in prognosis prediction microenvironment (TME) regulation colon poorly understood. Using bioinformatics, this study aimed to construct risk signature for cancer, which may provide means developing new effective treatment strategies. consensus...
Background: With the development of surgical instruments and growth professional expertise over past decades, laparoscopic pancreatoduodenectomy (LPD) is widely applied in different centers. However, there are still some controversies about safety this procedure. Meanwhile, perioperative outcomes affected by hospital size, surgeon experience, learning curve. The purpose study to compare short-term LPD with open (OPD) at stages Methods: We retrospectively analyzed clinical data 911 patients...
Abstract Background: It is important to identify deterioration in normotensive patients with acute pulmonary embolism (PE). This study aimed develop a tool for predicting among PE on admission. Methods: Clinical, laboratory, and computed tomography parameters were retrospectively collected who treated at Chinese center from January 2011 May 2020 admission into the hospital. The endpoint of was any adverse outcome within 30 days. Eligible randomized 2:1 derivation validation cohorts, nomogram...
Abstract Background: It is important to identify deterioration in normotensive patients with acute pulmonary embolism (PE). This study aimed develop a tool for predicting among PE on admission. Methods: Clinical, laboratory, and computed tomography parameters were retrospectively collected who treated at Chinese center from January 2011 May 2020 admission into the hospital. The endpoint of was any adverse outcome within 30 days. Eligible randomized 2:1 derivation validation cohorts, nomogram...
Abstract Background: It is important to identify deterioration in normotension patients with acute pulmonary embolism (PE). This study aimed develop a tool for predicting among normotensive PE on admission. Methods: Clinical, laboratory, and computed tomography parameters were retrospective collected who treated at Chinese center from January 2011 May 2020 admission into hospital. The endpoint of the was any adverse outcome within 30 days. eligible randomized 2:1 training validation...
Background: Identification of patients at a high-risk deterioration in non-high-risk acute pulmonary embolism (PE) is critical to make clinical decision. Nevertheless, current methods have modest discriminatory power, therefore better risk assessment are needed develop.Methods: A total 2,084 PE were divided into derivation cohort (1,221 patients), validation cohorts I and II (320 543 patients) according their hospital. Deterioration was defined as any adverse outcome within 30-day on...