- Acute Lymphoblastic Leukemia research
- Urinary and Genital Oncology Studies
- Bladder and Urothelial Cancer Treatments
- Gastrointestinal Tumor Research and Treatment
- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Childhood Cancer Survivors' Quality of Life
- Uterine Myomas and Treatments
- Mental Health Research Topics
- Neurotransmitter Receptor Influence on Behavior
- Acute Myeloid Leukemia Research
- Folate and B Vitamins Research
- Global Cancer Incidence and Screening
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Pancreatic and Hepatic Oncology Research
- Endometrial and Cervical Cancer Treatments
- Heart Failure Treatment and Management
- Esophageal Cancer Research and Treatment
- Mental Health Treatment and Access
- Genomics, phytochemicals, and oxidative stress
- Diabetes Treatment and Management
- Neuroscience and Neuropharmacology Research
- Treatment of Major Depression
- Prostate Cancer Diagnosis and Treatment
First Affiliated Hospital of Xi'an Jiaotong University
2016-2025
Xi'an Jiaotong University
2013-2024
Gansu Provincial Hospital
2019-2023
Nanjing Foreign Language School
2021
King University
2020
Peking University
2020
Clinical Research Management
2017
Chengdu University
2015
Nanjing Medical University
2005
Depression is the most common mental illness worldwide. It has become an important public health problem. This study aimed to determine global burden of depression and how it changed between 1990 2017. We used information on obtained by Global Burden Disease (GBD) from The age-standardized incidence rate (ASR) estimated annual percentage change (EAPC) were assess depression. number incident cases worldwide increased 172 million in 25,8 2017, representing increase 49.86%. ASR varied widely...
Schizophrenia is a serious health problem worldwide. This systematic analysis aims to quantify the burden of schizophrenia at global, regional and national levels using Global Burden Disease Study 2017 (GBD 2017).We collected detailed information on number incidence cases, disability-adjusted life years (DALYs) age-standardised rate (ASIR) DALYs (ASDR) during 1990-2017 from GBD 2017. The estimated annual percentage changes (EAPCs) in ASIR ASDR were calculated temporal trends...
Abstract Background Data on the incidence, mortality, and other burden of oral cancer as well their secular trends are necessary to provide policy‐makers with information needed allocate resources appropriately. The purpose this study was use Global Burden Disease (GBD) 2017 results estimate disability‐adjusted life years (DALYs) for from 1990 2017. Methods We collected detailed data GBD global DALYs attributable corresponding age‐standardized rates (ASRs) were calculated. estimated annual...
The purpose was to quantify the health effects of tobacco using data from 2019 Global Burden Disease study.
Background. Inflammation plays a key role in the pathophysiology and progression of acute kidney injury (AKI). Red cell distribution width (RDW) to platelet ratio (RPR) is novel inflammatory index, its prognostic effect on critically ill patients with AKI rarely investigated. This work aimed at investigating association between RPR in-hospital mortality these patients. Methods. Data were extracted from Medical Information Mart for Intensive Care III database. All-cause death during...
Breast cancer is a common malignant tumor which affects health of women and multidrug resistance (MDR) one the main factors leading to failure chemotherapy. This study was conducted establish paclitaxel-resistant breast cell line nude mice models explore underlying mechanisms MDR.The drug-sensitive MCF-7 (MCF-7/S) exposed in stepwise escalating paclitaxel (TAX) induce resistant MCF-7/TAX. Cell sensitivity drugs growth curves were measured by MTT assay. Changes morphology ultrastructure...
This study used data from the Global Burden of Disease Study 2019 (GBD 2019) to determine differences in incidence and mortality prostate cancer (PCa) between China USA 1990 2019.The age-standardized rates (ASIRs) death (ASDRs) were extracted GBD 2019. Annual percentage changes relative risks ASIR ASDR calculated using joinpoint regression analysis age-period-cohort models, respectively.The PCa continually increased 2019, while it 1994 then decreased until 2015, slightly again The did not...
Objective: To determine the relationships between dopamine D2 receptor gene polymorphisms and risk of schizophrenia using meta-analysis. Method: The PubMed, Embase, China National Knowledge Infrastructure databases were searched to identify relevant literature published up February 2016. allele contrast model was used. STATA software used for statistical analysis, with odds ratios (ORs) 95% confidence intervals (CIs) calculated evaluate associations schizophrenia. Meta-regression publication...
Abstract Background Eating disorders (ED) have increasingly become a global topic of concern for public health. A better understanding ED incidence is basic requirement improving its management. However, the temporal trend in China still unknown. Methods The rates from 1990 to 2017 were collected Global Burden Disease Study database according following: subtype, i.e. anorexia nervosa (AN) and bulimia (BN); sex; age group. average annual percent changes relative risks calculated using...
The first milestone (in 2020) of the End Tuberculosis (TB) Strategy World Health Organization was a 20% reduction in TB incidence rate compared with 2015 baseline. This study aimed to determine and how it has changed since at global, regional, country levels.This used most recent data from Global Burden Disease 2017 extract rates levels. annual percentage change (APCIR) based on calculated evaluate trend changes various levels, including globally regional An APCIR -4% 2020 is considered...
Cancers frequently develop resistance to paclitaxel but the underlying molecular mechanisms remain be determined. We have investigated proteins that are associated with in human breast cancer MCF-7 cells using proteomic analysis. Paclitaxel resistant (MCF-7/P) were established by escalating concentrations of drug-sensitive (MCF-7/S). The global protein profiles MCF-7/P and MCF-7/S compared two-dimensional gel electrophoresis (2-DE) matrix-assisted laser desorption/ionization time flight mass...
The associations between CYP1A1 polymorphisms and risk of leukemia have been studied extensively, but the results inconsistent. Therefore, in this study, we performed a meta-analysis to clarify three (T3801C, A2455G, C4887A) with risks acute lymphoblastic (ALL), myeloid (AML), chronic (CML). Medline, EMBASE, China National Knowledge Infrastructure databases were searched collect relevant studies published up April 20, 2015. extracted data analyzed statistically, pooled odds ratios 95%...