A5087497995- Congenital heart defects research
- Extracellular vesicles in disease
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- RNA modifications and cancer
- MicroRNA in disease regulation
- Ferroptosis and cancer prognosis
- Genomic variations and chromosomal abnormalities
- Glycosylation and Glycoproteins Research
Chinese People's Liberation Army
2021
Air Force Medical University
2021
Xijing Hospital
2021
Abstract In patients with prostate cancer (PCa), bone lesions appear osteoblastic in radiographs; however, pathological fractures frequently occur PCa patients, and resorption is observed all metastatic under histopathologic assessment. The mechanisms that balance the activities of osteoblasts osteoclasts remain unclear. We unexpectedly discovered exosomes are critical mediators regulation homeostasis results osteoclastic thereby promotes tumor growth bone. evaluated how derived from...
Necroptosis is a new type of programmed cell death and involves the occurrence development various cancers. Moreover, aberrantly expressed lncRNA can also affect tumorigenesis, migration, invasion. However, there are few types research on necroptosis-related (NRL), especially in kidney renal clear carcinoma (KIRC). In this study, we analyzed sequencing data obtained from TGCA-KIRC dataset, then applied LASSO COX analysis to identify 6 NRLs (AC124854.1, AL117336.1, DLGAP1-AS2, EPB41L4A-DT,...
We report a 15-year-old boy with cat-eye syndrome (CES) without short stature or intellectual disorder. The was confirmed by cytogenetic and high-resolution chromosome microarray analysis (CMA). G-banding karyotype the de novo of patient. Also, CMA result showed 1.76 Mb tetrasomy proximal 22Q11.1 ⟶ 22Q11.21 consistent CES {arr22q11.1q11.21 (16,888,899–18,644,241) X4}, typical small type I chromosome. patient has many basic characteristics CES; however, he is taller than his peers instead...