A5042646702- Plant Reproductive Biology
- Plant Molecular Biology Research
- Biochemical and Structural Characterization
- RNA modifications and cancer
- Reproductive Biology and Fertility
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Genetic Mapping and Diversity in Plants and Animals
- Reproductive System and Pregnancy
- Single-cell and spatial transcriptomics
- Plant nutrient uptake and metabolism
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Congenital heart defects research
- Epigenetics and DNA Methylation
- Renal and related cancers
- Genomics and Phylogenetic Studies
- Sperm and Testicular Function
- Machine Learning in Bioinformatics
Peking University
2024
Peking University Third Hospital
2024
Huazhong University of Science and Technology
2022
Huazhong Agricultural University
2020-2022
ORCID
2020
Protein phylogenetic analysis focuses on the evolutionary relationships among related protein sequences and can help researchers infer functions developmental trajectories. With advent of big data era, existing methods, including distance matrix character-based are facing challenges in both running time application scope. Here, we developed an R package that call CProtMEDIAS is useful for analysis. In contrast to utilizes dimensionality reduction algorithms digitize multiple sequence...
Abstract Background: The CLV3 / ESR-RELATED ( CLE ) gene family encodes small secreted peptides (SSPs) and plays vital roles in plant growth development by promoting cell-to-cell communication. prediction classification of genes is challenging because their low sequence similarity. Results: We developed a machine learning-aided method for predicting using motif-specific residual score matrix novel clustering based on the Euclidean distance 12 amino acid residues from motif site-weight...
As a member of the CLAVATA3 (CLV3)/EMBRYO SURROUNDING REGION (CLE) family, dodecapeptide tracheary element differentiation inhibitory factor (TDIF) has major impact on vascular development in plants. However, influence polymorphisms TDIF peptide motif activity remains poorly understood. The model plant, Arabidopsis provides fast and effective tool for assaying homologs. Five homologs from group 93 CLE genes switchgrass ( Panicum virgatum ), perennial biomass crop, named PvTDIF-like PvTDIFL )...
Abstract Background: The CLV3 / ESR-RELATED ( CLE ) gene family encodes small secreted peptides (SSPs) and plays vital roles in plant growth development by promoting cell-to-cell communication. prediction classification of genes is challenging because their low sequence similarity. Results: We developed a machine learning-aided method for predicting using motif-specific residual score matrix novel clustering based on the Euclidean distance 12 amino acid residues from motif site-weight...
Abstract Background: The CLV3 / ESR-RELATED ( CLE ) gene family encodes small secreted peptides (SSPs) and plays vital roles in plant growth development through cell-to-cell communication. prediction classification of genes is challenging because their low sequence similarity. Results: We developed a machine learning-aided method for predicting by using motif-specific residual score matrix novel clustering based on the Euclidean distance 12 amino acid residues from motifs site-weight...