A5103282616- Assisted Reproductive Technology and Twin Pregnancy
- Prenatal Screening and Diagnostics
- Pregnancy and preeclampsia studies
- Lymphoma Diagnosis and Treatment
- Cutaneous lymphoproliferative disorders research
- Ectopic Pregnancy Diagnosis and Management
- Gestational Diabetes Research and Management
- Birth, Development, and Health
- Fetal and Pediatric Neurological Disorders
- Ferroptosis and cancer prognosis
- Cancer Mechanisms and Therapy
- Genetic Syndromes and Imprinting
- Full-Duplex Wireless Communications
- Polyomavirus and related diseases
- Mechanisms of cancer metastasis
- Medical Imaging and Pathology Studies
- Sarcoma Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- Peptidase Inhibition and Analysis
- Epigenetics and DNA Methylation
- Ear and Head Tumors
- Immune Cell Function and Interaction
- Radiopharmaceutical Chemistry and Applications
- Intracerebral and Subarachnoid Hemorrhage Research
- Morinda citrifolia extract uses
Jilin University
2016-2025
Union Hospital
2016-2025
Peking University
2014-2024
Peking University Third Hospital
2014-2024
Union Hospital
2012-2022
Mayo Clinic
2017
Mayo Clinic in Arizona
2017
Guiyang University
2013
First Bethune Hospital of Jilin University
2013
Abstract Background Maternal lipid metabolism fluctuations have been shown to increase the risk of adverse pregnancy outcomes. However, there is no consensus over what constitutes normal maternal values during twin pregnancy. Therefore, aim this study was establish a serum reference range for Methods A retrospective survey conducted, from 2011 2021, at Peking University Third Hospital. total 881 pregnancies, with data early and middle were included. After excluding those outcomes, we...
Abstract Functional E‐cadherin loss, a hallmark of epithelial‐mesenchymal transition ( EMT ), is important for metastasis. However, the mechanism Snail2 in hepatocellular carcinoma HCC ) and metastasis remains unclear. Here, we showed that was upregulated primary , significantly increased during transforming growth factor‐β‐induced liver cell . Snail2‐overexpressing knockdown lines have been established to determine its function H3K9 methylation H3K4 H3K56 acetylation were downregulated at...
Changes in cervical length twin pregnancies exhibit various patterns, but it is unclear whether the mechanism underlying spontaneous preterm birth (sPTB) consistent. The existence of detailed phenomena singleton also unclear.
Abstract Background Selective intrauterine fetal growth restriction (sIUGR) in monochorionic diamniotic twins, especially types 2&3 with abnormal umbilical artery Doppler, results increased risk of fetal/perinatal mortality and postnatal disability. We investigate whether the hair metabolome profiles neonates were associated pathophysiological differences across different clinical forms sIUGR twins. Methods Hair samples collected at delivery from 10 pairs type 1 8 11 twins without sIUGR....
To describe our preliminary experience in the application of microwave ablation for selective fetal reduction complicated monochorionic multiple pregnancies.In this prospective study, 45 consecutive pregnancies that underwent from July 2015 to February 2017 were analyzed first case onward. All patients managed at Peking University Third Hospital Beijing, China.There cases (twins 40 and triplets five) treated by ablation. The median gestational age surgery was 21.3 weeks (range, 15.9-25.7...
Peripheral T-cell lymphomas (PTCLs) are aggressive non-Hodgkin with generally poor outcomes following standard therapy. Few candidate therapeutic targets have been identified to date. Retinoic acid receptor alpha (RARA) is a transcription factor that modulates cell growth and differentiation in response retinoids. While retinoids used treat some cutaneous (CTCLs), their mechanism of action the role RARA CTCL other mature remain poorly understood. After identifying PTCL RARAR394Q mutation, we...
Context: Hyaluronic acid (HA) plays critical roles in the structural skeleton, joint lubrication, renal function and cell signaling. We previously showed that partially N-butyrylated, low molecular weight, hyaluronic (BHA) exhibited an anti-inflammatory effect cultured human macrophage, where inflammation was induced either by a TL-4 agonist or weight HA itself, dose-dependent fashion. Objectives: To investigate anti-inflammatory, antioxidative, antihyperuricemic effects of BHA using animal...
Objective To investigate the diagnostic performance of 18 F-FDG PET/computed tomography (CT) for detection occult primary tumors in patients with squamous cell carcinoma unknown (SCCUP) head and neck. Patients From March 2016 to January 2020, 37 diagnosed as SCCUP before PET/CT were retrospectively reviewed. The diagnosis was made when an overt tumor location could not be found histologically proven cervical lymphadenopathy after a complete workup which includes full medical history,...
Abstract In perinatal medicine, intrauterine growth restriction (IUGR) is one of the greatest challenges. The etiology IUGR multifactorial, but most cases are thought to arise from placental insufficiency. However, identifying cause can be difficult due numerous confounding factors. Selective (sIUGR) would a good model investigate how impaired placentation affects fetal development, as discordance between monochorionic twins cannot explained by genetic or maternal Herein, we constructed and...
To explore differences among placental anastomoses, territory discordance, and umbilical cord insertion of twin-to-twin transfusion syndrome (TTTS) with without selective intrauterine growth restriction (sIUGR).This study retrospectively analyzed 57 patients TTTS who received conservative treatment finally delivered at the Department Obstetrics Gynecology Peking University Third Hospital from April 2014 to 2019. Nine patient's placentas were too broken finish perfusion, 48 kept for graph...
Diffuse large B-cell lymphoma (DLBCL) has been reported to have a significant association with the hepatitis B virus (HBV) infection. However, there no experimental evidence determine whether components of are expressed in lymphoid cells. In this study, we used immunohistochemical methods explore antigens DLBCL cells HBsAg-positive patients (HBsAg + DLBCL). HBx antigen was detected 48.9% HBsAg patients, and expression rate Pre-S2 57.2%. significantly associated high-level c-Myc, while not....
Abstract Background Unequal placental territory in monochorionic diamniotic twins is a primary cause of selective fetal growth restriction (sFGR), and vascular anastomoses play important role determining sFGR prognosis. This study investigated differences characteristics pregnancy outcomes cases with without thick arterio-arterial anastomosis (AAA). Methods A total 253 patients diagnosed between April 2013 2020 were retrospectively analyzed. An AAA greater than 2 mm diameter was defined as...
Iliac artery angiosarcoma is rare, and bone metastasis as its presenting initial symptom extremely rare. A 67-year-old man with a history of low back pain presented multiple MRI-identified lumbar sacrum lesions highly suggestive metastasis. On subsequent PET/CT scan, in addition to vertebrae pelvis hypermetabolism, lesion intense focal uptake was discovered within the lumen left common iliac artery. Dual-time point quantitative analysis revealed that lesion-to-liver ratio SUVmax...
The aim of the study was to investigate placental characteristics in spontaneous twin anemia polycythemia sequence.A retrospective case-control sequence, twin-to-twin transfusion syndrome and normal monochorionic diamniotic pregnancies performed. primary outcome characteristics.The prevalence artery-artery anastomoses sequence groups significantly lower than group (40.0% vs 33.3% 88.8%, respectively, P < .001). total number vascular (with range given parentheses) two control (3 [1-6] 5...