A5067328065- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Acute Ischemic Stroke Management
- Cardiac Imaging and Diagnostics
- CNS Lymphoma Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Aortic aneurysm repair treatments
- Aortic Disease and Treatment Approaches
- Cardiovascular Function and Risk Factors
- Congenital Heart Disease Studies
- Venous Thromboembolism Diagnosis and Management
- Pulmonary Hypertension Research and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Prostate Cancer Diagnosis and Treatment
- Medical Imaging and Analysis
- Advanced Radiotherapy Techniques
- Cardiac tumors and thrombi
- Heparin-Induced Thrombocytopenia and Thrombosis
- Adipokines, Inflammation, and Metabolic Diseases
- Protease and Inhibitor Mechanisms
- Glioma Diagnosis and Treatment
- Drug-Induced Adverse Reactions
- Diagnosis and Treatment of Venous Diseases
- Vascular anomalies and interventions
- Blood properties and coagulation
Kuopio University Hospital
1981-2022
University of Eastern Finland
2014-2020
Seoul National University Hospital
2017
Helsinki University Hospital
1979
The left atrial appendage (LAA) is the typical origin for intracardiac thrombus formation. Whether LAA morphology associated with increased stroke/TIA risk controversial and, if it does, which morphological type most predisposes to We assessed in stroke patients cryptogenic or suspected cardiogenic etiology and age- gender-matched healthy controls. volume were analyzed by cardiac computed tomography 111 (74 males; mean age 60 ± 11 years) acute ischemic of other than known fibrillation (AF)....
Background/Aim: We aimed to analyze the diagnostic value of total tau (T-tau), S-100 calcium-binding protein B (S100B) and neuron-specific enolase (NSE) as blood-based biomarkers in acute ischemic stroke (AIS) or transient attack (TIA), their correlation with symptom severity, infarct size, etiology outcome. Patients Methods: A 102 patients 35 TIA were analyzed. Subacute (63.8±50.1 h) plasma T-tau was measured single-molecule array (Simoa) method NSE S100B evaluated for comparison....
We report here the first population-based incidence rates and prognosis of primary central nervous system lymphoma (PCNSL) in Finland.Finnish Cancer Registry data by histological diagnosis tumor location (2007-2017) for cases with diffuse large B-cell lymphoma.During 2007-2017, 392 new PCNSL were reported (195 males, 197 females). The average age-adjusted was 0.68/100,000 person-years. Incidence males 0.74/100,000 females 0.63/100,000, respectively. highest, 2.93/100,000, among people aged...
Abstract Objectives The aim of this study was to evaluate whether the orientation heart, measured as an angle between long axis heart and ascending aorta midline (heart-aorta-angle, HAA), associates with aortic (AA) dilatation. Furthermore, association HAA wall shear stress (WSS) studied. Methods retrospectively in 1000 consecutive coronary artery computed tomographic angiography (CCTA) images patients low-to-moderate pretest probability for disease (CAD). To effects on AA flow, 4D flow MRI...
Left atrial appendage (LAA) dilatation and morphology may influence an individual's risk for intracardiac thrombi ischemic stroke. LAA size can be evaluated using cardiac computed tomography (cCT). The present study the reproducibility of volume assessments.A total 149 patients (47 females; mean age 60.9±10.6 years) with suspected cardioembolic stroke/transient attack underwent cCT. Image quality was rated based on four categories. Ten were selected from each image category (N = 40)...
The majority of intracardiac thrombi form in the left atrial appendage (LAA). Enlargement this structure, together with certain morphological features, may indicate a predisposition to formation and subsequent cardioembolic stroke. Thus far, studies on LAA morphology have largely focused those patients fibrillation (AF). Taking different approach, we investigated variation consecutive patient population without AF. We evaluated 808 (529 females; mean age 52.5±9.9 years) who underwent...
To clarify the prevalence and risk factors of ascending aortic (AA) dilatation according to ESC 2014 guidelines.This study included 1000 consecutive patients scheduled for diagnostic coronary artery computed tomographic angiography. AA diameter was retrospectively measured in 3 planes: sinus valsalva, sinotubular junction, tubular part. The threshold set > 40 mm which has been suggested as an upper normal limit guidelines on diseases. Aortic size index (ASI) using ratio between body surface...
We evaluated soluble urokinase-type plasminogen activator receptor (suPAR) levels in different stroke subtypes and assessed their prognostic value regarding 5-year outcomes.The study included 117 patients (81 males; mean=age 61±11 years) with suspected cardioembolic whose plasma suPAR concentration was assessed. Altogether, 20 (17.1%) suffered from as a result of cardioembolism, 12 (10.3%) large-artery atherosclerosis, 9 (7.7%) small-vessel disease, 11 (9.4%) both etiology, 65 (55.6%) had...
A chronically elevated level of von Willebrand factor (vWF) is a common finding in patients with cardiovascular diseases. Obesity well-recognized risk for thrombotic complications including ischemic stroke, and it has been linked increased plasma vWF. We evaluated whether levels vWF associate areas visceral (VAT), pericardial (PAT), subcutaneous adipose tissue (SAT) compartments acute/subacute stroke.A total 69 stroke suspected cardiogenic etiology were examined. The antigen (vWF-ag) was...
Background/Aim: Dilatation of the main pulmonary artery (mPA) is a common incidental finding in chest imaging and often leads to consultation. The aim this study was determine prevalence mPA dilatation coronary CT angiography (CCTA) population. Patients Methods: investigated 985 consecutive patients scheduled for diagnostic CCTA. transverse axial diameter measured. estimated using different reference values (Framingham Heart Study: 28.9 mm males 26.9 females, Bozlar: 29.5 both genders...
Purpose or ObjectiveTo suggest an optimal planning target volume (PTV) margin in stereotactic body radiotherapy (SBRT) of the spine. Material and MethodsFrom December 2014 to July 2016, 40 patients received 42 fractions SBRT for spinal tumors thoracic lumbosacral spines using a volumetric modulated arc therapy technique patient immobilization.Before treatment, kilovoltage cone-beam CT (CBCT) images were obtained 4 degrees freedom (DoF) correction alignment (translation + yaw).After...
Abstract Introduction Epidemiological studies on the prevalence of ascending aortic (AA) dilatation are scanty. Purpose To clarify AA according to ESC 2014 guidelines and study its risk factors. Methods This retrospective included 1000 consecutive patients scheduled for diagnostic coronary artery computer tomography angiography (CCTA) with low moderate pretest probability disease (CAD). diameter was measured at 3 planes; sinus valsalva, sinotubular junction tubular part. Threshold set >40...
Abstract PurposeWe report here the first population-based incidence rates and prognosis of primary central nervous system lymphoma (PCNSL) in Finland. MethodsFinnish Cancer Registry data by histological diagnosis tumor location (2007-2017) for cases with diffuse large B-cell lymphoma.ResultsDuring 2007–2017, 416 new PCNSL were reported (202 males, 214 females). The average age-adjusted males vs. females 2007-2009, 2010-2012, 2013-2015 2016-2017 was 0.57/100,000 0.48/100,000 person-years,...
Abstract Background: We report here the first population-based incidence rates and prognosis of primary central nervous system lymphoma (PCNSL) in Finland. Methods: Finnish Cancer Registry data by histological diagnosis tumor location (2007-2017) for cases with diffuse large B-cell lymphoma. Results: During 2007–2017, 392 new PCNSL were reported (195 males, 197 females). The average age-adjusted was 0.68/100.000 person-years. Incidence males 0.74/100.000 females 0.63/100.000, respectively....