Shylaja Arulkumar

ORCID: 0000-0001-5313-0595
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About
Contact & Profiles
Research Areas
  • Monoclonal and Polyclonal Antibodies Research
  • Glycosylation and Glycoproteins Research
  • Graphene and Nanomaterials Applications
  • Herpesvirus Infections and Treatments
  • Bone Tissue Engineering Materials
  • Viral Infections and Vectors
  • Immunodeficiency and Autoimmune Disorders
  • Click Chemistry and Applications
  • Peptidase Inhibition and Analysis
  • Cytomegalovirus and herpesvirus research
  • Virology and Viral Diseases
  • Nanoparticle-Based Drug Delivery
  • Supramolecular Self-Assembly in Materials
  • Toxoplasma gondii Research Studies
  • Mosquito-borne diseases and control
  • Tissue Engineering and Regenerative Medicine
  • Electrospun Nanofibers in Biomedical Applications

Epitaxial Technologies (United States)
2021

Institute for Stem Cell Biology and Regenerative Medicine
2014

Christian Medical College
2014

Christian Medical College & Hospital
2014

We report the use of multiplexed T. gondii IgG, IgM test on plasmonic gold (pGOLD) platform in setting infection by analyzing 244 sera from Nice, France (seroconversion, chronically infected, non-infected and newborns serum samples). Results were compared with commercial tests for detection IgG their overall clinical final interpretation a complete serological profile. The results agreement in, respectively, 95% 93% kits. When comparing profile, reached 99.5% 97.7% IgM, respectively. This...

10.1016/j.diagmicrobio.2016.09.001 article EN cc-by-nc-nd Diagnostic Microbiology and Infectious Disease 2016-09-13

Strain-promoted azide-alkyne cycloaddition (SPAAC) reactions like click chemistry have the potential to be highly scalable, robust, and cost-effective methods for generating small- large-molecule conjugates a variety of applications. However, despite method improvements, rates copper-based continue much faster than copper-free reactions, which makes broader deployment challenging from safety compatibility standpoint. In this study, we used zwitterionic detergent, namely, lauryldimethylamine...

10.1021/acsomega.2c03481 article EN cc-by-nc-nd ACS Omega 2022-09-20

Abstract Background Due to the diversity of serotypes, exacerbated by phenomenon serotype replacement, there remains an unmet medical need for a pneumococcal conjugate vaccine (PCV) containing additional serotypes. Using cell-free protein synthesis (CFPS) platform produce enhanced carrier (eCRM®) based on CRM197 sequence, Vaxcyte is developing PCV encompassing over 30 The eCRM contains multiple insertions non-native amino acid para-azidomethyl-L-phenylalanine (pAMF) that facilitates...

10.1093/ofid/ofab466.1241 article EN cc-by Open Forum Infectious Diseases 2021-11-01
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