Christopher S. McLaughlin

ORCID: 0000-0001-5319-2753
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About
Contact & Profiles
Research Areas
  • Autism Spectrum Disorder Research
  • Genetics and Neurodevelopmental Disorders
  • Attention Deficit Hyperactivity Disorder
  • Functional Brain Connectivity Studies
  • EEG and Brain-Computer Interfaces
  • Genomic variations and chromosomal abnormalities
  • Child Development and Digital Technology
  • Muscle activation and electromyography studies
  • Virology and Viral Diseases
  • Children's Physical and Motor Development
  • Tactile and Sensory Interactions
  • RNA and protein synthesis mechanisms
  • Neural dynamics and brain function
  • Genomics and Phylogenetic Studies
  • Chromosomal and Genetic Variations
  • Congenital heart defects research

Icahn School of Medicine at Mount Sinai
2020-2022

Mount Sinai Hospital
2021

University of Vienna
2019

The University of Texas at Austin
2019

Sichuan University
2019

Université Claude Bernard Lyon 1
2019

University of St Andrews
2019

McDaniel College
2015

Corollary discharge (CD) signals are “copies” of motor sent to sensory regions that allow animals adjust consequences self-generated actions. Autism spectrum disorder (ASD) is characterized by and deficits, which may be underpinned altered CD signaling. We evaluated oculomotor using the blanking task, measures influence saccades on visual perception, in 30 children with ASD 35 typically developing (TD) children. Participants were instructed make a saccade target. Upon initiation, presaccadic...

10.1167/jov.21.8.9 article EN cc-by-nc-nd Journal of Vision 2021-08-05

The current study used eye tracking to investigate attention and recognition memory in Phelan-McDermid syndrome (PMS), a rare genetic disorder characterized by intellectual disability, motor delays, high likelihood of comorbid autism spectrum (ASD). Social deficits represent core feature ASD, including decreased propensity orient or show preference for social stimuli. We visual paired-comparison task with both non-social images, assessing looking behavior novel image versus previously viewed...

10.1186/s11689-021-09400-2 article EN cc-by Journal of Neurodevelopmental Disorders 2021-12-01

Phelan-McDermid Syndrome (PMS) is a rare genetic disorder caused by deletion or sequence variation in the SHANK3 gene at terminal chromosome 22 that confers high likelihood of comorbid autism spectrum (ASD). Whereas individuals with idiopathic ASD (iASD) can demonstrate diverse patterns sensory differences, PMS mainly characterized hyporesponsiveness. This study used electrophysiology and passive auditory habituation paradigm to test for neural markers EEG was recorded from 15 PMS, iASD, 16...

10.3389/fnins.2022.815933 article EN cc-by Frontiers in Neuroscience 2022-05-03

A common example of social differences in autism spectrum disorder is poor modulation reciprocal gaze, including reduced duration eye contact and difficulty detecting the aim another’s gaze. It remains unclear, however, whether such are specific to domain, or instead indicative broader alterations processes visual engagement disengagement disorder. To assess children with experience altered attention, stimuli, we implemented a gap-overlap eye-tracking paradigm consisting both nonsocial...

10.1177/13623613211010072 article EN Autism 2021-05-09

The current study used eye tracking to investigate attention and recognition memory in Phelan-McDermid syndrome (PMS), a rare genetic disorder characterized by intellectual disability, motor delays, high likelihood of comorbid autism spectrum (ASD). Social deficits represent core feature ASD, including decreased propensity orient or show preference for social stimuli. Here, we visual paired comparison task with both non-social images, assessing looking behavior novel image versus...

10.31234/osf.io/42d3f preprint EN 2020-02-20

Autism spectrum disorder (ASD) is a neurodevelopmental disorder, where motor impairments are common and impact individuals across the lifespan. A growing body of work suggests that alterations in predictive processes may contribute to ASD symptomatology, such anticipation upcoming events disrupted. Such an alteration could potentially planning. Motor planning deficits not, however, unique ASD. Attention-deficit/hyperactivity (ADHD) has been linked execution difficulties, ADHD commonly...

10.31234/osf.io/9sjgh preprint EN 2020-09-24
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